Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr5 132018242 . C A CCDS4158.1:NM_000589.3:c.425aCg>aAg_NP_000580.1:p.142T>K Homo sapiens interleukin 4 (IL4), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4ydy 2 P05112 100.0 1e-92 X-RAY
 2015-03-04 THR B:119 I:118 57.0 0.407 H -58.6 -52.1 57.0 0.407 0.0 HOH
 2.915
 OG1
 O
THR D:119 J:118 61.0 0.436 H -65.4 -41.9 NA NA NA
1hik 1 P05112 100.0 2e-92 X-RAY
 1996-01-29 THR A:118 A:118 85.0 0.607 H -68.3 -47.9 48.0 0.343 0.264 A:P05112:0.264
 HOH
 3.665
 CG2
 O
1iar 1 P05112 100.0 2e-92 X-RAY
 2000-03-03 THR A:118 A:118 55.0 0.393 H -63.1 -46.6 55.0 0.393 0.0 HOH
 8.069
 CG2
 O
1rcb 1 P05112 100.0 2e-92 X-RAY
 1993-10-31 THR A:118 A:118 90.0 0.643 H -69.0 -57.7 38.0 0.271 0.372 A:P05112:0.371
 HOH
 3.042
 CG2
 O
2b8u 1 P05112 100.0 2e-92 X-RAY
 2006-05-30 THR A:118 A:118 70.0 0.5 H -59.5 -46.6 70.0 0.5 0.0 HOH
 2.714
 O
 O
2int 1 P05112 100.0 2e-92 X-RAY
 1994-01-31 THR A:118 A:118 69.0 0.493 H -64.8 -45.0 37.0 0.264 0.229 A:P05112:0.229
3bpl 1 P05112 100.0 2e-92 X-RAY
 2008-02-05 THR A:118 A:118 82.0 0.586 H -65.4 -42.6 21.0 0.15 0.436 C:P31785:0.436
 HOH
 2.915
 OG1
 O
3bpn 1 P05112 100.0 2e-92 X-RAY
 2008-02-05 THR A:118 A:118 76.0 0.543 H -62.9 -52.6 34.0 0.243 0.3 C:P78552:0.3
 HOH
 6.945
 CB
 O
1hij 1 P05112 99.22 1e-91 X-RAY
 1996-01-29 THR A:118 A:118 67.0 0.479 H -73.8 -56.9 34.0 0.243 0.236 A:P05112:0.236
 HOH
 3.604
 CG2
 O
1hzi 1 P05112 99.22 1e-91 X-RAY
 2001-08-29 THR A:118 A:118 69.0 0.493 H -58.2 -46.6 69.0 0.493 0.0 SO4
HOH
 8.393
2.729
 N
OG1
 O2
O
2d48 1 P05112 99.22 1e-91 X-RAY
 2006-05-30 THR A:118 A:118 69.0 0.493 H -59.4 -45.2 69.0 0.493 0.0 HOH
 2.754
 OG1
 O
1bbn 1 P05112 96.21 2e-91 NMR
 1993-10-31 THR A:122 A:122 63.0 0.45 H -64.6 -45.4 63.0 0.45 0.0
2b8z 1 P05112 99.22 2e-91 X-RAY
 2006-05-30 THR A:118 A:118 71.0 0.507 H -53.3 -47.7 71.0 0.507 0.0 HOH
 2.582
 O
 O
2b8x 1 P05112 99.22 4e-91 X-RAY
 2006-05-30 THR A:118 A:118 67.0 0.479 H -58.2 -44.8 67.0 0.479 0.0 SO4
HOH
 8.646
2.696
 N
O
 O4
O
2b90 1 P05112 98.45 1e-90 X-RAY
 2006-05-30 THR A:118 A:118 68.0 0.486 H -64.2 -44.3 68.0 0.486 0.0 HOH
 2.796
 O
 O
2b8y 1 P05112 98.45 2e-90 X-RAY
 2006-05-30 THR A:118 A:118 71.0 0.507 H -56.3 -46.5 71.0 0.507 0.0 HOH
 2.747
 OG1
 O
2b91 1 P05112 98.45 3e-90 X-RAY
 2006-05-30 THR A:118 A:118 68.0 0.486 H -62.5 -46.7 68.0 0.486 0.0 HOH
 2.724
 O
 O
5fhx 1 P05112 100.0 6e-88 X-RAY
 2016-03-30 THR A:113 A:118 74.0 0.529 H -56.9 -48.3 74.0 0.529 0.0
6oel 1 P05112 93.8 8e-87 X-RAY
 2019-08-07 VAL A:118 A:118 78.0 0.503 H -64.1 -42.1 29.0 0.187 0.316 C:P31785:0.316
3qb7 1 D4HNR6 93.8 1e-86 X-RAY
 2012-04-25 VAL A:121 A:118 57.0 0.368 H -68.4 -43.3 57.0 0.368 0.0
VAL B:121 B:118 77.0 0.497 H -53.5 -34.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05112-f1 1 P05112 100.0 9e-113 THR A:142 A:142 71.0 0.507 H -61.6 -51.0