Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr7 130027748 . C A CCDS5820.1:NM_001868.2:c.1156Cgc>Agc_NP_001859.1:p.386R>S Homo sapiens carboxypeptidase A1 (pancreatic) (CPA1), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5om9 1 P15085 100.0 0.0 X-RAY
 2017-08-09 ARG A:386 A:276 154.0 0.684 S -61.4 -43.6 75.0 0.333 0.351 B:P15085:0.351
 HOH
 2.790
 O
 O
ARG B:386 B:276 143.0 0.636 S -55.1 -50.4 94.0 0.418 0.218 A:P15085:0.218
 HOH
 2.981
 NH1
 O
4uf4 1 P15085 99.76 0.0 X-RAY
 2016-01-20 ARG A:386 A:386 156.0 0.693 S -56.5 -46.0 156.0 0.693 0.0 HOH
 2.814
 O
 O
ARG B:386 B:386 143.0 0.636 S -58.7 -46.3 NA NA NA
1pca 1 P09954 81.55 0.0 X-RAY
 1993-10-31 ARG A:371 A:276 132.0 0.587 S -71.2 -28.1 132.0 0.587 0.0 HOH
 2.687
 NH2
 O
2v77 1 P15085 100.0 0.0 X-RAY
 2008-07-01 ARG A:276 A:276 195.0 0.867 S -53.5 -49.4 195.0 0.867 0.0 HOH
 2.985
 N
 O
ARG B:276 B:276 206.0 0.916 S -51.8 -50.2 NA NA NA
4uee 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ARG A:276 A:276 216.0 0.96 S -48.2 -55.2 130.0 0.578 0.382 B:P15085:0.382
 HOH
 3.012
 N
 O
ARG B:276 B:276 199.0 0.884 S -47.2 -51.3 126.0 0.56 0.324 A:P15085:0.324
 HOH
 3.164
 N
 O
4uef 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ARG A:276 A:386 202.0 0.898 S -51.1 -49.1 202.0 0.898 0.0 HOH
 2.948
 NH1
 O
ARG B:276 B:386 204.0 0.907 S -60.8 -44.5 NA NA NA
4uez 1 P15085 100.0 0.0 X-RAY
 2016-01-20 ARG A:276 A:386 203.0 0.902 S -47.8 -48.4 203.0 0.902 0.0 LFF
HOH
 9.923
2.787
 N
NH1
 C19
O
ARG B:276 B:386 205.0 0.911 S -50.3 -49.3 NA NA NA
6i6z 1 P15085 100.0 0.0 X-RAY
 2018-12-12 ARG A:276 A:386 202.0 0.898 S -53.8 -50.4 119.0 0.529 0.369 B:P15085:0.369
 HOH
 2.909
 NH1
 O
ARG B:276 B:386 200.0 0.889 S -58.6 -47.5 115.0 0.511 0.378 A:P15085:0.378
 HOH
 2.952
 NH1
 O
3fju 1 P15085 100.0 0.0 X-RAY
 2008-12-30 ARG A:275 A:276 203.0 0.902 S -57.4 -49.8 165.0 0.733 0.169 B:P19399:0.169
 HOH
 2.585
 NH1
 O
1pyt 2 P00730 81.23 0.0 X-RAY
 1997-01-27 ARG B:276 B:276 210.0 0.933 S -57.4 -37.1 163.0 0.724 0.209 A:P00730:0.209
 HOH
 2.469
 O
 O
3kgq 1 P00730 81.23 0.0 X-RAY
 2010-10-27 ARG A:276 A:276 140.0 NA S -58.6 -53.7 140.0 NA NA HOH
 3.040
 N
 O
1arm 1 P00730 80.91 0.0 X-RAY
 1996-08-17 ARG A:276 A:276 204.0 0.907 S -55.2 -48.5 204.0 0.907 0.0 HOH
 2.956
 N
 O
1ee3 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ARG A:276 P:276 195.0 0.867 S -52.9 -52.7 195.0 0.867 0.0 HOH
 2.961
 N
 O
1ell 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ARG A:276 P:276 195.0 0.867 S -51.0 -51.0 195.0 0.867 0.0 HOH
 2.966
 N
 O
1elm 1 P00730 80.91 0.0 X-RAY
 2002-06-26 ARG A:276 P:276 192.0 0.853 S -51.4 -52.7 192.0 0.853 0.0 HOH
 2.952
 N
 O
1yme 1 P00730 80.91 0.0 X-RAY
 1997-02-12 ARG A:276 A:276 196.0 0.871 S -53.3 -52.0 196.0 0.871 0.0 HOH
 2.955
 N
 O
1zlh 1 P00730 80.91 0.0 X-RAY
 2005-07-05 ARG A:276 A:276 104.0 NA S -58.3 -54.7 93.0 NA NA B:58374130:NA
 HOH
 3.146
 N
 O
2abz 1 P00730 80.91 0.0 X-RAY
 2006-01-31 ARG A:276 A:276 201.0 0.893 S -68.5 -55.9 32.0 0.142 0.751 D:P81511:0.293
B:P00730:0.48
ARG B:276 B:276 169.0 0.751 S -59.3 -61.7 102.0 0.453 0.298 A:P00730:0.298
3hlp 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 ARG A:276 A:276 198.0 0.88 S -57.0 -53.3 198.0 0.88 0.0 MPD
HOH
 9.472
2.860
 N
NH1
 C5
O
ARG B:276 B:276 119.0 NA S -58.6 -49.0 NA NA NA
3huv 1 A6H6Y4 80.91 0.0 X-RAY
 2010-06-02 ARG A:276 A:276 199.0 0.884 S -64.0 -54.8 199.0 0.884 0.0 HOH
 2.725
 O
 O
3i1u 1 A6H6Y4 80.91 0.0 X-RAY
 2009-11-17 ARG A:276 A:276 203.0 0.902 S -56.3 -51.6 203.0 0.902 0.0 GOL
HOH
 9.508
2.695
 O
O
 O3
O
1hdq 1 P00730 81.43 0.0 X-RAY
 2001-11-15 ARG A:276 A:276 187.0 0.831 S -50.5 -49.6 187.0 0.831 0.0 HOH
 2.915
 NH2
 O
2ctb 1 P00730 81.43 0.0 X-RAY
 1994-01-31 ARG A:276 A:276 189.0 0.84 S -53.5 -49.6 189.0 0.84 0.0 HOH
 3.008
 N
 O
2ctc 1 P00730 81.43 0.0 X-RAY
 1994-01-31 ARG A:276 A:276 184.0 0.818 S -53.3 -48.3 184.0 0.818 0.0 HOH
 3.102
 N
 O
1arl 1 P00730 81.11 0.0 X-RAY
 1996-08-01 ARG A:276 A:276 198.0 0.88 S -51.7 -56.0 198.0 0.88 0.0 HOH
 3.175
 N
 O
1cpx 1 P00730 81.11 0.0 X-RAY
 1998-08-05 ARG A:276 A:276 205.0 0.911 S -59.0 -50.6 205.0 0.911 0.0 HOH
 3.097
 N
 O
1f57 1 P00730 81.11 0.0 X-RAY
 2000-09-06 ARG A:276 A:276 198.0 0.88 S -61.7 -57.3 198.0 0.88 0.0 HOH
 2.837
 O
 O
1m4l 1 P00730 81.11 0.0 X-RAY
 2003-01-10 ARG A:276 A:276 200.0 0.889 S -59.4 -46.2 200.0 0.889 0.0 HOH
 2.781
 O
 O
2rfh 1 A6H6Y4 81.11 0.0 X-RAY
 2008-04-22 ARG A:276 A:276 205.0 0.911 S -51.8 -51.7 205.0 0.911 0.0 HOH
 2.959
 N
 O
3fvl 1 P00730 81.11 0.0 X-RAY
 2010-01-12 ARG A:276 A:276 178.0 0.791 S -55.4 -48.8 141.0 0.627 0.164 C:P00730:0.164
 HOH
 3.026
 N
 O
ARG B:276 C:276 176.0 0.782 S -56.2 -47.8 164.0 0.729 0.053 A:P00730:0.053
 HOH
 2.756
 NH2
 O
ARG C:276 E:276 170.0 0.756 S -54.5 -55.9 170.0 0.756 0.0 HOH
 3.044
 N
 O
3fx6 1 P00730 81.11 0.0 X-RAY
 2009-08-25 ARG A:276 A:276 180.0 0.8 S -54.4 -49.7 180.0 0.8 0.0 HOH
 2.990
 N
 O
ARG B:276 C:276 180.0 0.8 S -54.5 -49.6 169.0 0.751 0.049 A:P00730:0.049
 HOH
 2.649
 O
 O
ARG C:276 E:276 196.0 0.871 S -59.1 -49.3 196.0 0.871 0.0 HOH
 2.920
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p15085-f1 1 P15085 100.0 0.0 ARG A:386 A:386 171.0 0.76 S -59.1 -40.4