Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104120348 . G A CCDS782.1:NM_020978.4:c.1227atG>atA_NP_066188.1:p.409M>I Homo sapiens amylase, alpha 2B (pancreatic) (AMY2B), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3old 1 P04746 98.99 0.0 X-RAY
 2011-04-13 MET A:394 A:394 0.0 0.0 H -81.0 -21.7 0.0 0.0 0.0 HOH
 3.540
 CG
 O
3ole 1 P04746 98.99 0.0 X-RAY
 2011-04-13 MET A:394 A:394 0.0 0.0 H -82.8 -23.7 0.0 0.0 0.0 HOH
 3.514
 CG
 O
3olg 1 P04746 98.99 0.0 X-RAY
 2011-04-13 MET A:394 A:394 0.0 0.0 H -78.8 -25.6 0.0 0.0 0.0 HOH
 3.625
 CG
 O
3oli 1 P04746 98.99 0.0 X-RAY
 2011-04-13 MET A:394 A:394 0.0 0.0 H -79.2 -21.1 0.0 0.0 0.0 HOH
 3.613
 CG
 O
6z8l 1 P04746 98.79 0.0 X-RAY
 2020-12-02 MET A:394 A:394 0.0 0.0 H -73.7 -28.0 0.0 0.0 0.0 HOH
 2.962
 HG3
 O
1b2y 1 P04746 98.79 0.0 X-RAY
 2000-02-16 MET A:394 A:394 0.0 0.0 H -80.1 -23.7 0.0 0.0 0.0 HOH
 4.862
 O
 O
1bsi 1 P04746 98.59 0.0 X-RAY
 1999-05-18 MET A:394 A:394 0.0 0.0 H -81.7 -23.6 0.0 0.0 0.0 HOH
 4.857
 N
 O
1cpu 1 P04746 98.59 0.0 X-RAY
 1999-06-14 MET A:394 A:394 0.0 0.0 H -80.5 -26.1 0.0 0.0 0.0 HOH
 3.547
 CG
 O
1hny 1 P04746 98.59 0.0 X-RAY
 1996-03-08 MET A:394 A:394 0.0 0.0 H -80.0 -26.7 0.0 0.0 0.0 HOH
 3.784
 CG
 O
1u2y 1 P04746 98.59 0.0 X-RAY
 2004-09-07 MET A:394 A:394 0.0 0.0 H -83.0 -23.8 0.0 0.0 0.0 HOH
 3.776
 CG
 O
1u30 1 P04746 98.59 0.0 X-RAY
 2004-09-07 MET A:394 A:394 0.0 0.0 H -81.7 -20.1 0.0 0.0 0.0 HOH
 4.946
 N
 O
1u33 1 P04746 98.59 0.0 X-RAY
 2004-09-07 MET A:394 A:394 0.0 0.0 H -77.2 -25.7 0.0 0.0 0.0 HOH
 3.498
 CG
 O
1xcw 1 P04746 98.59 0.0 X-RAY
 2004-12-07 MET A:394 A:394 0.0 0.0 H -79.4 -24.1 0.0 0.0 0.0 HOH
 4.827
 N
 O
1xcx 1 P04746 98.59 0.0 X-RAY
 2004-12-07 MET A:394 A:394 0.0 0.0 H -81.1 -24.1 0.0 0.0 0.0 HOH
 4.925
 N
 O
1xd0 1 P04746 98.59 0.0 X-RAY
 2004-12-07 MET A:394 A:394 0.0 0.0 H -80.2 -25.3 0.0 0.0 0.0 HOH
 4.825
 N
 O
1xd1 1 P04746 98.59 0.0 X-RAY
 2004-12-07 MET A:394 A:394 1.0 0.005 H -81.1 -20.4 1.0 0.005 0.0 HOH
 4.959
 N
 O
2qmk 1 P04746 98.59 0.0 X-RAY
 2008-03-25 MET A:394 A:394 0.0 0.0 H -79.6 -21.3 0.0 0.0 0.0 HOH
 3.698
 CG
 O
2qv4 1 P04746 98.59 0.0 X-RAY
 2008-03-25 MET A:394 A:394 0.0 0.0 H -81.1 -22.5 0.0 0.0 0.0 HOH
 3.646
 CG
 O
3bai 1 P04746 98.59 0.0 X-RAY
 2008-03-25 MET A:394 A:394 0.0 0.0 H -80.6 -24.2 0.0 0.0 0.0 HOH
 3.894
 CG
 O
3baj 1 P04746 98.59 0.0 X-RAY
 2008-03-25 MET A:394 A:394 0.0 0.0 H -80.4 -20.9 0.0 0.0 0.0 HOH
 4.874
 N
 O
3baw 1 P04746 98.59 0.0 X-RAY
 2008-03-25 MET A:394 A:394 0.0 0.0 H -83.5 -22.7 0.0 0.0 0.0 HOH
 3.573
 CG
 O
3ij7 1 P04746 98.59 0.0 X-RAY
 2009-10-27 MET A:394 A:394 0.0 0.0 H -78.3 -27.5 0.0 0.0 0.0 HOH
 3.531
 CG
 O
3ij8 1 P04746 98.59 0.0 X-RAY
 2009-10-27 MET A:394 A:394 0.0 0.0 H -81.1 -27.4 0.0 0.0 0.0 HOH
 3.484
 CG
 O
3ij9 1 P04746 98.59 0.0 X-RAY
 2009-10-27 MET A:394 A:394 0.0 0.0 H -81.4 -27.5 0.0 0.0 0.0 HOH
 3.559
 CG
 O
4gqq 1 P04746 98.59 0.0 X-RAY
 2012-10-24 MET A:394 A:394 0.0 0.0 H -82.2 -22.4 0.0 0.0 0.0 HOH
 4.869
 N
 O
4gqr 1 P04746 98.59 0.0 X-RAY
 2012-10-24 MET A:394 A:394 0.0 0.0 H -81.0 -26.2 0.0 0.0 0.0 HOH
 3.516
 CG
 O
4w93 1 P04746 98.59 0.0 X-RAY
 2015-07-15 MET A:394 A:394 0.0 0.0 H -80.9 -28.9 0.0 0.0 0.0 HOH
 3.487
 CG
 O
4x9y 1 P04746 98.59 0.0 X-RAY
 2014-12-31 MET A:394 A:394 0.0 0.0 H -78.5 -28.5 0.0 0.0 0.0 HOH
 2.922
 HG3
 O
5e0f 1 P04746 98.59 0.0 X-RAY
 2016-09-07 MET A:394 A:394 0.0 0.0 H -81.7 -26.7 0.0 0.0 0.0 HOH
 2.998
 HG3
 O
5emy 1 P04746 98.59 0.0 X-RAY
 2016-07-06 MET A:394 A:394 0.0 0.0 H -79.9 -28.1 0.0 0.0 0.0 HOH
 2.925
 HG3
 O
5kez 1 P04746 98.59 0.0 X-RAY
 2017-03-29 MET A:394 A:394 0.0 0.0 H -82.8 -25.9 0.0 0.0 0.0 HOH
 3.447
 CG
 O
5u3a 1 P04746 98.59 0.0 X-RAY
 2017-12-06 MET A:394 A:394 0.0 0.0 H -78.7 -28.5 0.0 0.0 0.0 HOH
 2.919
 HG3
 O
5va9 1 P04746 98.59 0.0 X-RAY
 2018-03-28 MET A:394 A:394 0.0 0.0 H -75.2 -31.0 0.0 0.0 0.0 HOH
 4.625
 N
 O
MET B:394 B:394 0.0 0.0 H -76.5 -31.0 NA NA NA
6obx 1 P04746 98.59 0.0 X-RAY
 2020-02-12 MET A:394 A:394 0.0 0.0 H -77.2 -30.1 0.0 0.0 0.0 HOH
 2.913
 HG3
 O
6ocn 1 P04746 98.59 0.0 X-RAY
 2020-02-12 MET A:394 A:394 0.0 0.0 H -78.3 -28.5 0.0 0.0 0.0 HOH
 2.963
 HG3
 O
1xgz 1 P04746 98.39 0.0 X-RAY
 2005-05-24 MET A:394 A:394 0.0 0.0 H -80.1 -25.8 0.0 0.0 0.0 HOH
 3.599
 CG
 O
1xh0 1 P04746 98.39 0.0 X-RAY
 2005-05-24 MET A:394 A:394 0.0 0.0 H -78.3 -23.5 0.0 0.0 0.0 HOH
 3.680
 CG
 O
1xh1 1 P04746 98.39 0.0 X-RAY
 2005-05-24 MET A:394 A:394 0.0 0.0 H -80.8 -26.5 0.0 0.0 0.0 HOH
 3.908
 CG
 O
1xh2 1 P04746 98.39 0.0 X-RAY
 2005-05-24 MET A:394 A:394 0.0 0.0 H -82.8 -23.9 0.0 0.0 0.0 HOH
 3.588
 CG
 O
3bak 1 P04746 98.39 0.0 X-RAY
 2008-03-25 MET A:394 A:394 1.0 0.005 H -81.2 -23.9 1.0 0.005 0.0 HOH
 3.981
 CG
 O
3bax 1 P04746 98.39 0.0 X-RAY
 2008-03-25 MET A:394 A:394 0.0 0.0 H -83.1 -23.1 0.0 0.0 0.0 HOH
 3.560
 CG
 O
3bay 1 P04746 98.39 0.0 X-RAY
 2008-03-25 MET A:394 A:394 1.0 0.005 H -77.9 -23.3 1.0 0.005 0.0 HOH
 5.033
 N
 O
1kgw 1 P04746 98.39 0.0 X-RAY
 2002-01-16 MET A:394 A:394 0.0 0.0 H -81.3 -27.2 0.0 0.0 0.0 HOH
 4.925
 N
 O
2cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 MET A:394 A:394 0.0 0.0 H -79.7 -26.7 0.0 0.0 0.0 HOH
 4.853
 N
 O
3cpu 1 P04746 98.39 0.0 X-RAY
 2001-06-30 MET A:394 A:394 0.0 0.0 H -81.2 -26.5 0.0 0.0 0.0 HOH
 4.885
 N
 O
5td4 1 P04746 98.39 0.0 X-RAY
 2016-11-02 MET A:394 A:394 0.0 0.0 H -76.3 -31.7 0.0 0.0 0.0 HOH
 3.688
 CG
 O
1kgx 1 P04746 98.39 0.0 X-RAY
 2002-01-16 MET A:394 A:394 0.0 0.0 H -79.2 -27.2 0.0 0.0 0.0 HOH
 3.549
 CG
 O
1kbb 1 P04746 98.39 0.0 X-RAY
 2002-04-10 MET A:394 A:394 0.0 0.0 H -82.6 -23.3 0.0 0.0 0.0 HOH
 4.998
 N
 O
1kgu 1 P04746 98.39 0.0 X-RAY
 2002-01-16 MET A:394 A:394 0.0 0.0 H -81.2 -25.7 0.0 0.0 0.0 HOH
 3.258
 CG
 O
1kb3 1 P04746 98.39 0.0 X-RAY
 2002-05-01 MET A:394 A:394 0.0 0.0 H -80.3 -24.3 0.0 0.0 0.0 HOH
 3.426
 CG
 O
1kbk 1 P04746 98.39 0.0 X-RAY
 2002-04-10 MET A:394 A:394 1.0 0.005 H -80.3 -25.5 1.0 0.005 0.0 HOH
 3.660
 CG
 O
1c8q 1 P04745 97.58 0.0 X-RAY
 2001-06-13 MET A:394 A:394 0.0 0.0 H -79.0 -24.3 0.0 0.0 0.0 HOH
 3.931
 CG
 O
1mfv 1 P04745 97.58 0.0 X-RAY
 2002-11-20 MET A:394 A:394 0.0 0.0 H -72.7 -32.2 0.0 0.0 0.0 HOH
 4.691
 N
 O
1smd 1 P04745 97.58 0.0 X-RAY
 1996-07-11 MET A:394 A:394 0.0 0.0 H -78.2 -23.2 0.0 0.0 0.0 HOH
 4.233
 CG
 O
1xv8 1 P04745 97.58 0.0 X-RAY
 2005-10-11 MET A:394 A:394 0.0 0.0 H -69.9 -30.0 0.0 0.0 0.0 HOH
 9.368
 O
 O
MET B:394 B:394 0.0 0.0 H -69.9 -30.1 0.0 0.0 0.0 HOH
 9.369
 O
 O
1q4n 1 P04745 97.38 0.0 X-RAY
 2004-03-16 MET A:394 X:394 0.0 0.0 H -71.4 -30.1 0.0 0.0 0.0 HOH
 3.517
 CG
 O
1z32 1 P04745 97.38 0.0 X-RAY
 2005-05-31 MET A:394 X:394 0.0 0.0 H -71.5 -29.7 0.0 0.0 0.0 HOH
 3.607
 CG
 O
1jxj 1 P04745 97.38 0.0 X-RAY
 2001-09-14 MET A:394 A:394 0.0 0.0 H -77.3 -26.7 0.0 0.0 0.0 HOH
 3.525
 CG
 O
1nm9 1 P04745 97.38 0.0 X-RAY
 2004-01-20 MET A:394 A:394 0.0 0.0 H -70.4 -30.7 0.0 0.0 0.0 HOH
 3.541
 CG
 O
3blk 1 P04745 97.38 0.0 X-RAY
 2008-11-25 MET A:394 A:394 0.0 0.0 H -78.4 -30.3 0.0 0.0 0.0 HOH
 3.664
 CG
 O
3blp 1 P04745 97.38 0.0 X-RAY
 2008-11-18 MET A:394 X:394 0.0 0.0 H -76.6 -30.5 0.0 0.0 0.0 HOH
 3.651
 CG
 O
1jxk 1 P04745 96.57 0.0 X-RAY
 2001-09-14 MET A:389 A:389 0.0 0.0 H -76.1 -27.2 0.0 0.0 0.0 HOH
 3.441
 CG
 O
1mfu 1 P04745 96.57 0.0 X-RAY
 2002-11-20 MET A:389 A:389 0.0 0.0 H -72.6 -29.7 0.0 0.0 0.0 HOH
 3.404
 CG
 O
3dhp 1 P04745 96.37 0.0 X-RAY
 2008-07-01 MET A:394 A:394 0.0 0.0 H -73.3 -29.4 0.0 0.0 0.0 HOH
 3.629
 CG
 O
1kxq 1 P00690 87.1 0.0 X-RAY
 2002-06-19 MET A:394 A:394 0.0 0.0 H -79.3 -26.8 0.0 0.0 0.0 HOH
 3.778
 CG
 O
MET B:394 B:394 0.0 0.0 H -78.8 -26.6 NA NA NA
MET C:394 C:394 0.0 0.0 H -83.4 -25.2 NA NA NA
MET D:394 D:394 0.0 0.0 H -81.7 -25.9 NA NA NA
1kxt 1 P00690 87.1 0.0 X-RAY
 2002-06-19 MET A:394 A:394 0.0 0.0 H -79.2 -23.5 0.0 0.0 0.0 HOH
 2.512
 CE
 O
MET C:394 C:394 0.0 0.0 H -74.9 -25.9 NA NA NA
MET E:394 E:394 0.0 0.0 H -87.4 -30.0 NA NA NA
1kxv 1 P00690 87.1 0.0 X-RAY
 2002-06-19 MET A:394 A:394 0.0 0.0 H -77.6 -27.6 0.0 0.0 0.0 HOH
 3.969
 CG
 O
MET B:394 B:394 0.0 0.0 H -79.1 -25.4 NA NA NA
1dhk 1 P00690 87.1 0.0 X-RAY
 1997-12-24 MET A:394 A:394 0.0 0.0 H -76.2 -27.4 0.0 0.0 0.0 HOH
 5.014
 O
 O
1ppi 1 P00690 87.1 0.0 X-RAY
 1995-05-24 MET A:394 A:394 0.0 0.0 H -80.0 -21.1 0.0 0.0 0.0 HOH
 5.028
 O
 O
3l2l 1 P00690 86.9 0.0 X-RAY
 2010-04-14 MET A:394 A:394 1.0 0.005 H -75.5 -26.8 1.0 0.005 0.0 HOH
 3.380
 HG3
 O
3l2m 1 P00690 86.9 0.0 X-RAY
 2010-04-14 MET A:394 A:394 1.0 0.005 H -80.7 -25.9 1.0 0.005 0.0 HOH
 3.671
 HG3
 O
1ua3 1 P00690 86.9 0.0 X-RAY
 2003-10-14 MET A:394 A:394 0.0 0.0 H -79.2 -28.5 0.0 0.0 0.0 HOH
 3.742
 CG
 O
1vah 1 P00690 86.9 0.0 X-RAY
 2005-04-26 MET A:394 A:394 1.0 0.005 H -78.4 -24.3 1.0 0.005 0.0 HOH
 4.963
 O
 O
1jfh 1 P00690 86.9 0.0 X-RAY
 1998-12-02 MET A:394 A:394 0.0 0.0 H -80.7 -22.2 0.0 0.0 0.0 HOH
 4.745
 N
 O
1ose 1 P00690 86.69 0.0 X-RAY
 1997-04-01 MET A:394 A:394 0.0 0.0 H -78.8 -27.6 0.0 0.0 0.0 HOH
 3.986
 CG
 O
1hx0 1 P00690 86.69 0.0 X-RAY
 2001-08-08 MET A:394 A:394 0.0 0.0 H -80.5 -28.2 0.0 0.0 0.0 HOH
 3.652
 CG
 O
1wo2 1 P00690 86.69 0.0 X-RAY
 2005-03-15 MET A:394 A:394 0.0 0.0 H -79.7 -23.0 0.0 0.0 0.0 HOH
 3.812
 CG
 O
1bvn 1 P00690 86.69 0.0 X-RAY
 1998-09-23 MET A:394 P:394 0.0 0.0 H -80.8 -21.0 0.0 0.0 0.0 HOH
 5.846
 N
 O
1pif 1 P00690 86.49 0.0 X-RAY
 1996-12-07 MET A:394 A:394 1.0 0.005 H -78.9 -28.5 1.0 0.005 0.0 HOH
 4.596
 CG
 O
1pig 1 P00690 86.49 0.0 X-RAY
 1996-12-07 MET A:394 A:394 1.0 0.005 H -77.8 -29.4 1.0 0.005 0.0 HOH
 4.585
 CG
 O
4x0n 1 P00690 86.49 0.0 X-RAY
 2015-11-25 MET A:394 A:394 0.0 0.0 H -81.2 -28.8 0.0 0.0 0.0 HOH
 4.955
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p19961-f1 1 P19961 100.0 0.0 MET A:409 A:409 0.0 0.0 H -74.2 -27.9
af-p04746-f1 1 P04746 98.83 0.0 MET A:409 A:409 0.0 0.0 H -72.9 -27.0
af-p0dte7-f1 1 P0DTE7 97.46 0.0 MET A:409 A:409 0.0 0.0 H -74.4 -27.5
af-p0dte8-f1 1 P0DTE8 97.46 0.0 MET A:409 A:409 0.0 0.0 H -74.3 -27.9
af-p0dub6-f1 1 P0DUB6 97.46 0.0 MET A:409 A:409 0.0 0.0 H -75.0 -26.9