Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104160204 . G A CCDS783.1:NM_000699.2:c.142Gct>Act_NP_000690.1:p.48A>T Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 ALA A:33 A:33 6.0 0.052 T -65.2 -56.5 6.0 0.052 0.0 HOH
 7.925
 CB
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 ALA A:33 A:33 10.0 0.087 T -64.4 -55.9 10.0 0.087 0.0 HOH
 4.064
 CB
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 ALA A:33 A:33 14.0 0.122 T -64.3 -56.6 14.0 0.122 0.0 HOH
 3.436
 CB
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 ALA A:33 A:33 5.0 0.043 T -64.5 -54.5 5.0 0.043 0.0 HOH
 5.010
 CB
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ALA A:33 A:33 11.0 0.096 T -64.4 -52.0 11.0 0.096 0.0 HOH
 4.030
 CB
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ALA A:33 A:33 11.0 0.096 T -69.6 -49.6 11.0 0.096 0.0 HOH
 2.993
 O
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 ALA A:33 A:33 10.0 0.087 T -68.3 -58.0 10.0 0.087 0.0 HOH
 3.211
 C
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ALA A:33 A:33 11.0 0.096 T -64.3 -53.6 11.0 0.096 0.0 HOH
 6.662
 O
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ALA A:33 A:33 10.0 0.087 T -64.9 -52.6 10.0 0.087 0.0 HOH
 4.032
 CB
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ALA A:33 A:33 14.0 0.122 T -64.7 -54.1 14.0 0.122 0.0 HOH
 7.035
 O
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 ALA A:33 A:33 14.0 0.122 T -67.5 -54.0 14.0 0.122 0.0 HOH
 6.864
 O
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ALA A:33 A:33 11.0 0.096 T -63.6 -60.3 11.0 0.096 0.0 HOH
 3.734
 CB
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ALA A:33 A:33 17.0 0.148 H -66.7 -55.4 17.0 0.148 0.0 HOH
 3.954
 CB
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ALA A:33 A:33 13.0 0.113 T -63.7 -56.0 13.0 0.113 0.0 HOH
 3.926
 CB
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ALA A:33 A:33 12.0 0.104 H -63.8 -58.1 12.0 0.104 0.0 HOH
 4.376
 CB
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 ALA A:33 A:33 13.0 0.113 T -64.6 -59.6 13.0 0.113 0.0 HOH
 2.927
 O
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ALA A:33 A:33 12.0 0.104 T -64.5 -54.9 12.0 0.104 0.0 HOH
 3.909
 CB
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ALA A:33 A:33 16.0 0.139 T -63.8 -54.3 16.0 0.139 0.0 HOH
 3.875
 CB
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 ALA A:33 A:33 10.0 0.087 T -65.1 -54.0 10.0 0.087 0.0 HOH
 3.715
 CB
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ALA A:33 A:33 17.0 0.148 T -67.2 -45.9 17.0 0.148 0.0 HOH
 6.488
 CB
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 ALA A:33 A:33 14.0 0.122 T -63.9 -60.3 14.0 0.122 0.0 HOH
 3.148
 C
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 ALA A:33 A:33 13.0 0.113 T -66.7 -53.4 13.0 0.113 0.0 HOH
 3.708
 CB
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 ALA A:33 A:33 13.0 0.113 T -63.3 -58.4 13.0 0.113 0.0 HOH
 2.751
 HB1
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 ALA A:33 A:33 13.0 0.113 T -66.0 -54.2 13.0 0.113 0.0 HOH
 2.744
 HB1
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 ALA A:33 A:33 14.0 0.122 T -65.1 -55.4 14.0 0.122 0.0 HOH
 2.744
 HB1
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 ALA A:33 A:33 12.0 0.104 T -68.6 -57.5 12.0 0.104 0.0 HOH
 3.996
 CB
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 ALA A:33 A:33 13.0 0.113 T -64.0 -59.0 13.0 0.113 0.0 HOH
 2.743
 HB1
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 ALA A:33 A:33 13.0 0.113 T -67.7 -53.9 13.0 0.113 0.0 HOH
 7.909
 CA
 O
ALA B:33 B:33 15.0 0.13 T -66.7 -54.5 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ALA A:33 A:33 13.0 0.113 T -63.2 -56.8 13.0 0.113 0.0 HOH
 2.763
 HB1
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 ALA A:33 A:33 12.0 0.104 T -64.2 -56.1 12.0 0.104 0.0 HOH
 2.780
 HB1
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ALA A:33 A:33 15.0 0.13 T -62.9 -58.2 15.0 0.13 0.0 HOH
 3.046
 C
 O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ALA A:33 A:33 14.0 0.122 T -64.9 -60.8 14.0 0.122 0.0 HOH
 3.209
 C
 O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ALA A:33 A:33 15.0 0.13 T -66.8 -55.0 15.0 0.13 0.0 HOH
 4.003
 CB
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 ALA A:33 A:33 15.0 0.13 T -66.5 -54.8 15.0 0.13 0.0 HOH
 3.859
 CB
 O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ALA A:33 A:33 13.0 0.113 T -62.0 -52.8 13.0 0.113 0.0 HOH
 7.864
 CB
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ALA A:33 A:33 9.0 0.078 T -66.3 -52.7 9.0 0.078 0.0 HOH
 4.067
 CB
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ALA A:33 A:33 8.0 0.07 T -64.0 -52.9 8.0 0.07 0.0 HOH
 3.239
 O
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ALA A:33 A:33 11.0 0.096 H -63.9 -54.8 11.0 0.096 0.0 HOH
 3.700
 CB
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 ALA A:33 A:33 9.0 0.078 T -63.6 -54.1 9.0 0.078 0.0 HOH
 3.762
 CB
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ALA A:33 A:33 10.0 0.087 T -66.2 -52.1 10.0 0.087 0.0 HOH
 3.080
 O
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ALA A:33 A:33 20.0 0.174 T -64.6 -60.4 20.0 0.174 0.0 HOH
 2.589
 O
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 ALA A:33 A:33 14.0 0.122 H -62.8 -54.8 14.0 0.122 0.0 HOH
 4.412
 CB
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ALA A:33 A:33 15.0 0.13 T -62.5 -55.6 15.0 0.13 0.0 HOH
 3.580
 CB
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 ALA A:33 A:33 11.0 0.096 T -64.7 -53.4 11.0 0.096 0.0 HOH
 2.757
 HB1
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 ALA A:33 A:33 13.0 0.113 T -63.4 -55.0 13.0 0.113 0.0 HOH
 5.693
 O
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ALA A:33 A:33 9.0 0.078 T -65.1 -55.2 9.0 0.078 0.0 HOH
 4.288
 CB
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 ALA A:33 A:33 12.0 0.104 T -60.1 -56.6 12.0 0.104 0.0 HOH
 3.715
 CB
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 ALA A:33 A:33 14.0 0.122 T -68.8 -50.7 14.0 0.122 0.0 HOH
 4.172
 CB
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 ALA A:33 A:33 13.0 0.113 T -62.8 -56.8 13.0 0.113 0.0 HOH
 3.985
 CB
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ALA A:33 A:33 8.0 0.07 T -63.0 -56.2 8.0 0.07 0.0 HOH
 8.052
 CB
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 ALA A:33 A:33 10.0 0.087 T -64.5 -55.9 10.0 0.087 0.0 HOH
 3.788
 CB
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 ALA A:33 A:33 12.0 0.104 T -68.5 -61.7 12.0 0.104 0.0 HOH
 3.925
 CB
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 ALA A:33 A:33 11.0 0.096 T -61.7 -60.6 11.0 0.096 0.0 HOH
 3.802
 CB
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 ALA A:33 A:33 10.0 0.087 T -63.2 -58.4 10.0 0.087 0.0 HOH
 7.798
 CB
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 ALA A:33 A:33 10.0 0.087 T -63.7 -56.1 10.0 0.087 0.0 HOH
 5.282
 O
 O
ALA B:33 B:33 10.0 0.087 T -63.7 -56.1 10.0 0.087 0.0 HOH
 5.282
 O
 O
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 ALA A:33 X:33 12.0 0.104 T -65.1 -56.1 12.0 0.104 0.0 HOH
 3.613
 CB
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 ALA A:33 A:33 13.0 0.113 T -63.4 -58.6 13.0 0.113 0.0 HOH
 7.200
 C
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 ALA A:33 X:33 12.0 0.104 T -69.6 -58.4 12.0 0.104 0.0 HOH
 3.755
 CB
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 ALA A:33 A:33 13.0 0.113 T -65.0 -58.4 13.0 0.113 0.0 HOH
 3.686
 CB
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 ALA A:33 A:33 12.0 0.104 T -65.2 -58.3 12.0 0.104 0.0 HOH
 7.596
 O
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 ALA A:33 X:33 13.0 0.113 T -65.0 -57.1 13.0 0.113 0.0 HOH
 3.804
 CB
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 ALA A:33 A:33 13.0 0.113 T -59.8 -60.3 13.0 0.113 0.0 HOH
 3.994
 CB
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 ALA A:33 A:33 13.0 0.113 T -61.2 -58.5 13.0 0.113 0.0 HOH
 3.741
 CB
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 ALA A:33 A:33 13.0 0.113 T -63.7 -57.2 13.0 0.113 0.0 HOH
 3.745
 CB
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:33 A:33 8.0 0.107 T -61.5 -60.5 8.0 0.107 0.0 HOH
 3.266
 C
 O
GLY B:33 B:33 11.0 0.147 T -64.3 -58.5 NA NA NA
GLY C:33 C:33 10.0 0.133 T -64.1 -60.3 NA NA NA
GLY D:33 D:33 5.0 0.067 T -64.8 -57.7 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:33 A:33 12.0 0.16 T -59.3 -64.5 12.0 0.16 0.0 HOH
 2.846
 CA
 O
GLY C:33 C:33 11.0 0.147 T -60.2 -54.1 NA NA NA
GLY E:33 E:33 8.0 0.107 T -62.4 -59.7 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 GLY A:33 A:33 6.0 0.08 T -65.0 -57.6 6.0 0.08 0.0 HOH
 3.217
 C
 O
GLY B:33 B:33 9.0 0.12 T -61.1 -59.9 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 GLY A:33 A:33 6.0 0.08 T -64.4 -60.0 6.0 0.08 0.0 HOH
 5.342
 CA
 O
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 GLY A:33 A:33 9.0 0.12 T -67.4 -60.7 9.0 0.12 0.0 HOH
 3.289
 O
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 GLY A:33 A:33 3.0 0.04 T -63.7 -71.3 3.0 0.04 0.0 HOH
 7.366
 N
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 GLY A:33 A:33 6.0 0.08 T -61.8 -58.6 6.0 0.08 0.0 HOH
 2.988
 HA3
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 GLY A:33 A:33 6.0 0.08 T -64.6 -61.7 6.0 0.08 0.0 HOH
 3.089
 HA3
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 GLY A:33 A:33 5.0 0.067 T -56.5 -62.8 5.0 0.067 0.0 EDO
HOH
 9.519
3.299
 N
C
 C2
O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 GLY A:33 A:33 5.0 0.067 T -64.5 -59.2 5.0 0.067 0.0 HOH
 3.296
 C
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 GLY A:33 A:33 8.0 0.107 T -62.4 -62.6 8.0 0.107 0.0 HOH
 3.574
 C
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 GLY A:33 A:33 6.0 0.08 T -62.1 -60.1 6.0 0.08 0.0 EDO
HOH
 9.489
3.268
 N
C
 C2
O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 GLY A:33 A:33 5.0 0.067 T -62.3 -62.3 5.0 0.067 0.0 EDO
HOH
 9.460
3.132
 N
C
 C2
O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 GLY A:33 P:33 8.0 0.107 T -53.3 -61.2 8.0 0.107 0.0 HOH
 6.458
 O
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 GLY A:33 A:33 6.0 0.08 T -61.8 -59.0 6.0 0.08 0.0 HOH
 3.209
 C
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 GLY A:33 A:33 7.0 0.093 T -66.1 -58.1 7.0 0.093 0.0 HOH
 3.543
 C
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 GLY A:33 A:33 4.0 0.053 T -63.0 -60.9 4.0 0.053 0.0 HOH
 5.245
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 ALA A:48 A:48 15.0 0.13 T -63.2 -52.3
af-p19961-f1 1 P19961 98.83 0.0 ALA A:48 A:48 15.0 0.13 T -61.9 -55.7
af-p0dte7-f1 1 P0DTE7 96.87 0.0 ALA A:48 A:48 15.0 0.13 T -59.3 -57.3
af-p0dte8-f1 1 P0DTE8 96.87 0.0 ALA A:48 A:48 14.0 0.122 T -62.7 -54.9
af-p0dub6-f1 1 P0DUB6 96.87 0.0 ALA A:48 A:48 15.0 0.13 T -63.0 -55.0