Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 104162279 . T A CCDS783.1:NM_000699.2:c.617gTt>gAt_NP_000690.1:p.206V>D Homo sapiens amylase, alpha 2A (pancreatic) (AMY2A), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
1b2y 1 P04746 100.0 0.0 X-RAY
 2000-02-16 VAL A:191 A:191 0.0 0.0 -70.8 145.9 0.0 0.0 0.0 HOH
 2.924
 O
 O
1bsi 1 P04746 99.8 0.0 X-RAY
 1999-05-18 VAL A:191 A:191 0.0 0.0 -69.0 152.1 0.0 0.0 0.0 HOH
 2.925
 O
 O
1cpu 1 P04746 99.8 0.0 X-RAY
 1999-06-14 VAL A:191 A:191 0.0 0.0 -67.2 146.3 0.0 0.0 0.0 HOH
 2.964
 O
 O
1hny 1 P04746 99.8 0.0 X-RAY
 1996-03-08 VAL A:191 A:191 0.0 0.0 -67.9 150.9 0.0 0.0 0.0 HOH
 2.813
 O
 O
1u2y 1 P04746 99.8 0.0 X-RAY
 2004-09-07 VAL A:191 A:191 0.0 0.0 -64.9 150.7 0.0 0.0 0.0 HOH
 2.883
 O
 O
1u30 1 P04746 99.8 0.0 X-RAY
 2004-09-07 VAL A:191 A:191 0.0 0.0 -67.7 142.3 0.0 0.0 0.0 HOH
 2.993
 O
 O
1u33 1 P04746 99.8 0.0 X-RAY
 2004-09-07 VAL A:191 A:191 0.0 0.0 -59.6 141.9 0.0 0.0 0.0 HOH
 2.921
 O
 O
1xcw 1 P04746 99.8 0.0 X-RAY
 2004-12-07 VAL A:191 A:191 0.0 0.0 -66.2 142.7 0.0 0.0 0.0 HOH
 2.969
 O
 O
1xcx 1 P04746 99.8 0.0 X-RAY
 2004-12-07 VAL A:191 A:191 0.0 0.0 -68.4 149.9 0.0 0.0 0.0 HOH
 2.920
 O
 O
1xd0 1 P04746 99.8 0.0 X-RAY
 2004-12-07 VAL A:191 A:191 0.0 0.0 -63.9 146.7 0.0 0.0 0.0 HOH
 2.880
 O
 O
1xd1 1 P04746 99.8 0.0 X-RAY
 2004-12-07 VAL A:191 A:191 0.0 0.0 -62.5 146.7 0.0 0.0 0.0 HOH
 3.055
 O
 O
2qmk 1 P04746 99.8 0.0 X-RAY
 2008-03-25 VAL A:191 A:191 0.0 0.0 -71.1 146.1 0.0 0.0 0.0 HOH
 2.744
 O
 O
2qv4 1 P04746 99.8 0.0 X-RAY
 2008-03-25 VAL A:191 A:191 0.0 0.0 -61.3 138.0 0.0 0.0 0.0 HOH
 2.850
 O
 O
3bai 1 P04746 99.8 0.0 X-RAY
 2008-03-25 VAL A:191 A:191 0.0 0.0 -65.3 146.6 0.0 0.0 0.0 HOH
 2.865
 O
 O
3baj 1 P04746 99.8 0.0 X-RAY
 2008-03-25 VAL A:191 A:191 0.0 0.0 -65.4 147.2 0.0 0.0 0.0 HOH
 2.954
 O
 O
3baw 1 P04746 99.8 0.0 X-RAY
 2008-03-25 VAL A:191 A:191 0.0 0.0 -69.6 141.6 0.0 0.0 0.0 HOH
 2.998
 O
 O
3ij7 1 P04746 99.8 0.0 X-RAY
 2009-10-27 VAL A:191 A:191 0.0 0.0 -63.7 145.9 0.0 0.0 0.0 HOH
 2.846
 O
 O
3ij8 1 P04746 99.8 0.0 X-RAY
 2009-10-27 VAL A:191 A:191 0.0 0.0 -60.6 143.3 0.0 0.0 0.0 HOH
 2.818
 O
 O
3ij9 1 P04746 99.8 0.0 X-RAY
 2009-10-27 VAL A:191 A:191 0.0 0.0 -63.1 147.0 0.0 0.0 0.0 HOH
 2.830
 O
 O
4gqq 1 P04746 99.8 0.0 X-RAY
 2012-10-24 VAL A:191 A:191 0.0 0.0 -63.4 143.6 0.0 0.0 0.0 HOH
 2.937
 O
 O
4gqr 1 P04746 99.8 0.0 X-RAY
 2012-10-24 VAL A:191 A:191 0.0 0.0 -65.9 146.0 0.0 0.0 0.0 HOH
 2.800
 O
 O
4w93 1 P04746 99.8 0.0 X-RAY
 2015-07-15 VAL A:191 A:191 0.0 0.0 -69.6 147.0 0.0 0.0 0.0 HOH
 2.853
 O
 O
4x9y 1 P04746 99.8 0.0 X-RAY
 2014-12-31 VAL A:191 A:191 0.0 0.0 -69.1 148.9 0.0 0.0 0.0 HOH
 2.823
 O
 O
5e0f 1 P04746 99.8 0.0 X-RAY
 2016-09-07 VAL A:191 A:191 0.0 0.0 -70.2 148.1 0.0 0.0 0.0 HOH
 2.872
 O
 O
5emy 1 P04746 99.8 0.0 X-RAY
 2016-07-06 VAL A:191 A:191 0.0 0.0 -66.4 146.9 0.0 0.0 0.0 HOH
 2.795
 O
 O
5kez 1 P04746 99.8 0.0 X-RAY
 2017-03-29 VAL A:191 A:191 0.0 0.0 -69.4 151.6 0.0 0.0 0.0 HOH
 2.833
 O
 O
5u3a 1 P04746 99.8 0.0 X-RAY
 2017-12-06 VAL A:191 A:191 0.0 0.0 -67.5 148.9 0.0 0.0 0.0 HOH
 2.794
 O
 O
5va9 1 P04746 99.8 0.0 X-RAY
 2018-03-28 VAL A:191 A:191 0.0 0.0 -65.7 148.1 0.0 0.0 0.0 HOH
 3.447
 C
 O
VAL B:191 B:191 0.0 0.0 -66.4 147.8 NA NA NA
6obx 1 P04746 99.8 0.0 X-RAY
 2020-02-12 VAL A:191 A:191 0.0 0.0 -68.6 147.6 0.0 0.0 0.0 HOH
 2.813
 O
 O
6ocn 1 P04746 99.8 0.0 X-RAY
 2020-02-12 VAL A:191 A:191 0.0 0.0 -68.0 148.1 0.0 0.0 0.0 HOH
 2.820
 O
 O
3old 1 P04746 99.8 0.0 X-RAY
 2011-04-13 VAL A:191 A:191 0.0 0.0 -64.8 145.4 0.0 0.0 0.0 HOH
 2.974
 O
 O
3ole 1 P04746 99.8 0.0 X-RAY
 2011-04-13 VAL A:191 A:191 0.0 0.0 -67.0 146.5 0.0 0.0 0.0 HOH
 2.819
 O
 O
3olg 1 P04746 99.8 0.0 X-RAY
 2011-04-13 VAL A:191 A:191 0.0 0.0 -69.6 139.4 0.0 0.0 0.0 HOH
 2.913
 O
 O
3oli 1 P04746 99.8 0.0 X-RAY
 2011-04-13 VAL A:191 A:191 0.0 0.0 -67.0 148.0 0.0 0.0 0.0 HOH
 2.860
 O
 O
1kgw 1 P04746 99.6 0.0 X-RAY
 2002-01-16 VAL A:191 A:191 0.0 0.0 -70.5 148.8 0.0 0.0 0.0 HOH
 2.727
 O
 O
1xgz 1 P04746 99.6 0.0 X-RAY
 2005-05-24 VAL A:191 A:191 0.0 0.0 -63.6 149.9 0.0 0.0 0.0 HOH
 2.937
 O
 O
1xh0 1 P04746 99.6 0.0 X-RAY
 2005-05-24 VAL A:191 A:191 0.0 0.0 -69.1 149.2 0.0 0.0 0.0 HOH
 2.974
 O
 O
1xh1 1 P04746 99.6 0.0 X-RAY
 2005-05-24 VAL A:191 A:191 0.0 0.0 -62.9 147.3 0.0 0.0 0.0 HOH
 2.955
 O
 O
1xh2 1 P04746 99.6 0.0 X-RAY
 2005-05-24 VAL A:191 A:191 0.0 0.0 -63.0 149.6 0.0 0.0 0.0 HOH
 2.961
 O
 O
3bak 1 P04746 99.6 0.0 X-RAY
 2008-03-25 VAL A:191 A:191 0.0 0.0 -64.9 149.0 0.0 0.0 0.0 HOH
 2.852
 O
 O
3bax 1 P04746 99.6 0.0 X-RAY
 2008-03-25 VAL A:191 A:191 0.0 0.0 -66.9 141.0 0.0 0.0 0.0 HOH
 2.921
 O
 O
3bay 1 P04746 99.6 0.0 X-RAY
 2008-03-25 VAL A:191 A:191 0.0 0.0 -59.8 152.6 0.0 0.0 0.0 HOH
 2.806
 O
 O
1kgx 1 P04746 99.6 0.0 X-RAY
 2002-01-16 VAL A:191 A:191 0.0 0.0 -64.8 145.5 0.0 0.0 0.0 HOH
 2.918
 O
 O
6z8l 1 P04746 99.6 0.0 X-RAY
 2020-12-02 VAL A:191 A:191 0.0 0.0 -64.6 145.1 0.0 0.0 0.0 HOH
 2.825
 O
 O
1kgu 1 P04746 99.6 0.0 X-RAY
 2002-01-16 VAL A:191 A:191 0.0 0.0 -69.5 148.1 0.0 0.0 0.0 HOH
 2.859
 O
 O
2cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 VAL A:191 A:191 0.0 0.0 -71.6 147.1 0.0 0.0 0.0 HOH
 2.917
 O
 O
3cpu 1 P04746 99.6 0.0 X-RAY
 2001-06-30 VAL A:191 A:191 0.0 0.0 -64.4 148.2 0.0 0.0 0.0 HOH
 2.695
 O
 O
5td4 1 P04746 99.6 0.0 X-RAY
 2016-11-02 VAL A:191 A:191 0.0 0.0 -70.8 147.9 0.0 0.0 0.0 HOH
 2.807
 O
 O
1kb3 1 P04746 99.6 0.0 X-RAY
 2002-05-01 VAL A:191 A:191 0.0 0.0 -60.9 150.0 0.0 0.0 0.0 HOH
 2.685
 O
 O
1kbb 1 P04746 99.6 0.0 X-RAY
 2002-04-10 VAL A:191 A:191 0.0 0.0 -68.2 146.5 0.0 0.0 0.0 HOH
 2.877
 O
 O
1kbk 1 P04746 99.6 0.0 X-RAY
 2002-04-10 VAL A:191 A:191 0.0 0.0 -66.1 150.6 0.0 0.0 0.0 HOH
 2.937
 O
 O
1c8q 1 P04745 96.98 0.0 X-RAY
 2001-06-13 VAL A:191 A:191 0.0 0.0 -55.1 143.4 0.0 0.0 0.0 HOH
 2.662
 O
 O
1mfv 1 P04745 96.98 0.0 X-RAY
 2002-11-20 VAL A:191 A:191 0.0 0.0 -61.9 141.7 0.0 0.0 0.0 HOH
 2.800
 O
 O
1smd 1 P04745 96.98 0.0 X-RAY
 1996-07-11 VAL A:191 A:191 0.0 0.0 -63.9 140.1 0.0 0.0 0.0 HOH
 2.841
 O
 O
1xv8 1 P04745 96.98 0.0 X-RAY
 2005-10-11 VAL A:191 A:191 0.0 0.0 -64.6 148.7 0.0 0.0 0.0
VAL B:191 B:191 0.0 0.0 -64.6 148.7 0.0 0.0 0.0
1z32 1 P04745 96.77 0.0 X-RAY
 2005-05-31 VAL A:191 X:191 0.0 0.0 -65.6 148.8 0.0 0.0 0.0 HOH
 2.798
 O
 O
1jxj 1 P04745 96.77 0.0 X-RAY
 2001-09-14 VAL A:191 A:191 0.0 0.0 -63.5 143.7 0.0 0.0 0.0 HOH
 2.761
 O
 O
1q4n 1 P04745 96.77 0.0 X-RAY
 2004-03-16 VAL A:191 X:191 0.0 0.0 -55.2 139.5 0.0 0.0 0.0 HOH
 2.691
 O
 O
1nm9 1 P04745 96.77 0.0 X-RAY
 2004-01-20 VAL A:191 A:191 0.0 0.0 -61.5 139.6 0.0 0.0 0.0 HOH
 2.802
 O
 O
3blk 1 P04745 96.77 0.0 X-RAY
 2008-11-25 VAL A:191 A:191 0.0 0.0 -66.2 141.0 0.0 0.0 0.0 HOH
 2.968
 O
 O
3blp 1 P04745 96.77 0.0 X-RAY
 2008-11-18 VAL A:191 X:191 0.0 0.0 -58.7 144.9 0.0 0.0 0.0 HOH
 2.923
 O
 O
1jxk 1 P04745 95.97 0.0 X-RAY
 2001-09-14 VAL A:191 A:191 0.0 0.0 -64.6 140.8 0.0 0.0 0.0 HOH
 2.863
 O
 O
1mfu 1 P04745 95.97 0.0 X-RAY
 2002-11-20 VAL A:191 A:191 0.0 0.0 -60.6 140.2 0.0 0.0 0.0 HOH
 2.883
 O
 O
3dhp 1 P04745 95.77 0.0 X-RAY
 2008-07-01 VAL A:191 A:191 0.0 0.0 -65.0 147.3 0.0 0.0 0.0 HOH
 2.888
 O
 O
1kxq 1 P00690 86.9 0.0 X-RAY
 2002-06-19 VAL A:191 A:191 0.0 0.0 -64.5 142.5 0.0 0.0 0.0 HOH
 2.940
 O
 O
VAL B:191 B:191 0.0 0.0 -65.8 143.3 NA NA NA
VAL C:191 C:191 0.0 0.0 -64.8 144.0 NA NA NA
VAL D:191 D:191 0.0 0.0 -67.5 149.9 NA NA NA
1kxt 1 P00690 86.9 0.0 X-RAY
 2002-06-19 VAL A:191 A:191 0.0 0.0 -49.1 138.8 0.0 0.0 0.0 HOH
 2.863
 O
 O
VAL C:191 C:191 0.0 0.0 -52.0 141.1 NA NA NA
VAL E:191 E:191 0.0 0.0 -54.5 142.4 NA NA NA
1kxv 1 P00690 86.9 0.0 X-RAY
 2002-06-19 VAL A:191 A:191 0.0 0.0 -65.6 150.6 0.0 0.0 0.0 HOH
 2.872
 O
 O
VAL B:191 B:191 0.0 0.0 -66.6 146.6 NA NA NA
1dhk 1 P00690 86.9 0.0 X-RAY
 1997-12-24 VAL A:191 A:191 0.0 0.0 -63.9 140.7 0.0 0.0 0.0 HOH
 2.242
 O
 H2
1ppi 1 P00690 86.9 0.0 X-RAY
 1995-05-24 VAL A:191 A:191 0.0 0.0 -66.5 140.4 0.0 0.0 0.0 HOH
 2.833
 O
 O
1vah 1 P00690 86.69 0.0 X-RAY
 2005-04-26 VAL A:191 A:191 0.0 0.0 -70.8 140.4 0.0 0.0 0.0 HOH
 2.902
 O
 O
3l2l 1 P00690 86.69 0.0 X-RAY
 2010-04-14 VAL A:191 A:191 0.0 0.0 -73.3 148.9 0.0 0.0 0.0 HOH
 2.974
 HA
 O
3l2m 1 P00690 86.69 0.0 X-RAY
 2010-04-14 VAL A:191 A:191 0.0 0.0 -67.2 144.1 0.0 0.0 0.0 HOH
 7.018
 H
 O
1ua3 1 P00690 86.69 0.0 X-RAY
 2003-10-14 VAL A:191 A:191 0.0 0.0 -62.0 146.3 0.0 0.0 0.0 HOH
 2.883
 O
 O
1jfh 1 P00690 86.69 0.0 X-RAY
 1998-12-02 VAL A:191 A:191 0.0 0.0 -64.4 140.2 0.0 0.0 0.0 HOH
 2.940
 O
 O
1ose 1 P00690 86.49 0.0 X-RAY
 1997-04-01 VAL A:191 A:191 0.0 0.0 -62.5 143.4 0.0 0.0 0.0 HOH
 2.799
 O
 O
1hx0 1 P00690 86.49 0.0 X-RAY
 2001-08-08 VAL A:191 A:191 0.0 0.0 -66.2 146.8 0.0 0.0 0.0 HOH
 2.821
 O
 O
1wo2 1 P00690 86.49 0.0 X-RAY
 2005-03-15 VAL A:191 A:191 0.0 0.0 -61.6 139.4 0.0 0.0 0.0 EDO
HOH
 9.891
2.859
 O
O
 O2
O
1bvn 1 P00690 86.49 0.0 X-RAY
 1998-09-23 VAL A:191 P:191 0.0 0.0 -67.3 143.3 0.0 0.0 0.0 HOH
 3.048
 O
 O
1pif 1 P00690 86.29 0.0 X-RAY
 1996-12-07 VAL A:191 A:191 0.0 0.0 -67.6 141.7 0.0 0.0 0.0 HOH
 2.972
 O
 O
1pig 1 P00690 86.29 0.0 X-RAY
 1996-12-07 VAL A:191 A:191 0.0 0.0 -63.7 143.6 0.0 0.0 0.0 HOH
 2.829
 O
 O
4x0n 1 P00690 86.29 0.0 X-RAY
 2015-11-25 VAL A:191 A:191 0.0 0.0 -65.2 144.7 0.0 0.0 0.0 HOH
 2.932
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p04746-f1 1 P04746 100.0 0.0 VAL A:206 A:206 0.0 0.0 -64.8 148.5
af-p19961-f1 1 P19961 98.83 0.0 VAL A:206 A:206 0.0 0.0 -65.7 150.4
af-p0dte7-f1 1 P0DTE7 96.87 0.0 VAL A:206 A:206 0.0 0.0 -66.0 149.8
af-p0dte8-f1 1 P0DTE8 96.87 0.0 VAL A:206 A:206 0.0 0.0 -66.2 149.6
af-p0dub6-f1 1 P0DUB6 96.87 0.0 VAL A:206 A:206 0.0 0.0 -65.5 149.0