Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 116932127 . C A CCDS887.1:NM_000701.7:c.821gCt>gAt_NP_000692.2:p.274A>D Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4hqj 1 P05024 98.14 0.0 X-RAY
 2013-10-02 ALA A:272 A:267 88.0 0.765 T -144.8 -20.9 88.0 0.765 0.0
ALA D:272 C:267 60.0 0.522 -145.8 -177.1 NA NA NA
4hyt 1 P05024 98.14 0.0 X-RAY
 2013-06-26 ALA A:272 A:267 3.0 0.026 H -60.9 -41.9 3.0 0.026 0.0 MG
 8.768
 O
 MG
ALA D:272 C:267 3.0 0.026 H -60.9 -41.8 NA NA NA
4res 1 P05024 98.14 0.0 X-RAY
 2015-01-28 ALA A:272 A:267 3.0 0.026 H -59.2 -54.4 3.0 0.026 0.0 K
 7.980
 O
 K
ALA D:272 C:267 2.0 0.017 H -60.1 -54.9 NA NA NA
4ret 1 P05024 98.14 0.0 X-RAY
 2015-01-28 ALA A:272 A:267 3.0 0.026 H -60.3 -43.0 3.0 0.026 0.0 MG
 8.937
 O
 MG
ALA D:272 C:267 3.0 0.026 H -60.5 -43.0 NA NA NA
7evx 1 P05024 98.14 0.0 X-RAY
 2021-07-07 ALA A:272 A:267 1.0 0.009 H -62.3 -40.3 1.0 0.009 0.0 NA
 8.375
 O
 NA
ALA D:272 C:267 3.0 0.026 H -62.4 -40.3 NA NA NA
3wgu 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 ALA A:267 A:267 48.0 0.417 S -66.2 -26.2 48.0 0.417 0.0
ALA D:267 C:267 34.0 0.296 S -5.4 -72.4 NA NA NA
3wgv 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 ALA A:267 A:267 50.0 0.435 S -64.3 -35.3 50.0 0.435 0.0
ALA D:267 C:267 36.0 0.313 S 2.3 -76.5 NA NA NA
7d91 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 2.0 0.017 H -63.2 -38.5 2.0 0.017 0.0 MG
HOH
 9.093
8.219
 O
O
 MG
O
7d92 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 3.0 0.026 H -64.1 -35.2 3.0 0.026 0.0 MG
HOH
 8.994
7.983
 O
O
 MG
O
7d93 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 0.0 0.0 H -58.9 -47.3 0.0 0.0 0.0 NA
 8.640
 O
 NA
ALA C:267 C:267 2.0 0.017 H -59.6 -46.9 NA NA NA
7d94 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 0.0 0.0 H -58.4 -47.5 0.0 0.0 0.0 NA
 8.517
 O
 NA
ALA D:267 C:267 2.0 0.017 H -60.3 -46.9 NA NA NA
7ddf 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 3.0 0.026 H -62.1 -35.9 3.0 0.026 0.0 NA
 8.772
 O
 NA
ALA D:267 C:267 3.0 0.026 H -63.1 -38.6 NA NA NA
7ddh 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 0.0 0.0 H -67.7 -38.1 0.0 0.0 0.0 NA
 8.648
 O
 NA
ALA D:267 C:267 1.0 0.009 H -68.1 -37.6 NA NA NA
7ddi 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 1.0 0.009 H -60.2 -39.6 1.0 0.009 0.0 NA
 8.623
 O
 NA
ALA D:267 C:267 2.0 0.017 H -60.6 -38.6 NA NA NA
7ddj 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 0.0 0.0 H -58.9 -47.2 0.0 0.0 0.0 NA
 8.741
 O
 NA
ALA D:267 C:267 2.0 0.017 H -60.2 -46.5 NA NA NA
7ddk 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 2.0 0.017 H -61.3 -39.4 2.0 0.017 0.0 NA
 8.197
 O
 NA
ALA D:267 C:267 2.0 0.017 H -61.0 -39.7 NA NA NA
7ddl 1 P05024 98.13 0.0 X-RAY
 2021-01-27 ALA A:267 A:267 1.0 0.009 H -60.6 -43.8 1.0 0.009 0.0 NA
 8.690
 O
 NA
ALA D:267 C:267 2.0 0.017 H -60.7 -43.8 NA NA NA
4xe5 1 Q08DA1 97.46 0.0 X-RAY
 2016-03-09 ALA A:272 A:272 3.0 0.026 H -66.9 -31.1 3.0 0.026 0.0 MG
 8.488
 O
 MG
3b8e 1 P05024 98.4 0.0 X-RAY
 2007-12-18 ALA A:249 A:267 1.0 0.009 H -69.1 44.7 1.0 0.009 0.0
ALA D:249 C:267 0.0 0.0 H -68.6 44.9 NA NA NA
3kdp 1 P05024 98.4 0.0 X-RAY
 2010-02-16 ALA A:249 A:267 0.0 0.0 H -84.0 -71.9 0.0 0.0 0.0 RB
 9.231
 O
 RB
ALA D:249 C:267 0.0 0.0 H -83.5 -70.6 NA NA NA
3n23 1 P05024 98.59 0.0 X-RAY
 2011-01-19 ALA A:243 A:267 0.0 0.0 H -74.6 -57.0 0.0 0.0 0.0
ALA D:243 C:267 0.0 0.0 H -79.2 -70.0 NA NA NA
2zxe 1 Q4H132 87.84 0.0 X-RAY
 2009-05-19 ALA A:279 A:274 0.0 0.0 H -61.1 -49.3 0.0 0.0 0.0 K
HOH
 8.965
6.293
 O
C
 K
O
3a3y 1 Q4H132 87.84 0.0 X-RAY
 2009-09-08 ALA A:279 A:274 0.0 0.0 H -66.2 -48.4 0.0 0.0 0.0 K
HOH
 9.086
7.042
 O
CB
 K
O
5avq 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.2 0.0 0.0 0.0 K
TL
 8.965
8.965
 O
O
 K
TL
5avr 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.2 0.0 0.0 0.0 K
TL
 8.964
8.964
 O
O
 K
TL
5avs 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.3 0.0 0.0 0.0 K
TL
 8.964
8.964
 O
O
 K
TL
5avt 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.3 0.0 0.0 0.0 K
TL
 8.964
8.964
 O
O
 K
TL
5avu 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.3 0.0 0.0 0.0 K
TL
 8.964
8.964
 O
O
 K
TL
5avv 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.2 0.0 0.0 0.0 K
TL
 8.964
8.964
 O
O
 K
TL
5avw 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.2 0.0 0.0 0.0 K
TL
 8.965
8.965
 O
O
 K
TL
5avx 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.2 0.0 0.0 0.0 K
TL
 8.966
8.966
 O
O
 K
TL
5avy 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.3 0.0 0.0 0.0 K
TL
 8.965
8.965
 O
O
 K
TL
5avz 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.2 0.0 0.0 0.0 K
TL
 8.965
8.965
 O
O
 K
TL
5aw0 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.2 0.0 0.0 0.0 K
TL
 8.964
8.964
 O
O
 K
TL
5aw1 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.3 0.0 0.0 0.0 K
TL
 8.965
8.965
 O
O
 K
TL
5aw2 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.2 0.0 0.0 0.0 K
TL
 8.964
8.964
 O
O
 K
TL
5aw3 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.3 0.0 0.0 0.0 K
TL
 8.965
8.965
 O
O
 K
TL
5aw4 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.3 0.0 0.0 0.0 K
RB
 8.965
8.965
 O
O
 K
RB
5aw5 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.1 -49.3 0.0 0.0 0.0 K
RB
 8.965
8.965
 O
O
 K
RB
5aw6 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.3 0.0 0.0 0.0 K
RB
 8.964
8.964
 O
O
 K
RB
5aw7 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.0 -49.3 0.0 0.0 0.0 K
RB
 8.965
8.965
 O
O
 K
RB
5aw8 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -61.2 -49.1 0.0 0.0 0.0 RB
 8.966
 O
 RB
5aw9 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 ALA A:279 A:274 0.0 0.0 H -64.6 -50.3 0.0 0.0 0.0 K
HOH
 8.986
6.370
 O
O
 K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05023-f1 1 P05023 100.0 0.0 ALA A:274 A:274 8.0 0.07 H -60.2 -36.8
af-p13637-f1 1 P13637 87.88 0.0 ALA A:264 A:264 9.0 0.078 H -61.0 -35.9
af-p50993-f1 1 P50993 86.71 0.0 ALA A:272 A:272 1.0 0.009 H -60.0 -37.3