Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 116942124 . T A CCDS887.1:NM_000701.7:c.2531cTt>cAt_NP_000692.2:p.844L>H Homo sapiens ATPase Na+/K+ transporting subunit alpha 1 (ATP1A1), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4hqj 1 P05024 98.14 0.0 X-RAY
 2013-10-02 LEU A:842 A:837 0.0 0.0 S -90.1 -23.9 0.0 0.0 0.0
LEU D:842 C:837 0.0 0.0 S -88.6 -23.9 NA NA NA
4hyt 1 P05024 98.14 0.0 X-RAY
 2013-06-26 LEU A:842 A:837 1.0 0.006 S -71.0 -65.7 1.0 0.006 0.0 17F
 8.316
 N
 N1
LEU D:842 C:837 1.0 0.006 S -70.7 -65.5 NA NA NA
4res 1 P05024 98.14 0.0 X-RAY
 2015-01-28 LEU A:842 A:837 2.0 0.012 S -73.0 -62.7 2.0 0.012 0.0
LEU D:842 C:837 2.0 0.012 S -73.1 -63.3 NA NA NA
4ret 1 P05024 98.14 0.0 X-RAY
 2015-01-28 LEU A:842 A:837 2.0 0.012 S -70.6 -63.3 2.0 0.012 0.0 17F
 7.789
 N
 O4
LEU D:842 C:837 1.0 0.006 S -70.5 -63.4 NA NA NA
7evx 1 P05024 98.14 0.0 X-RAY
 2021-07-07 LEU A:842 A:837 6.0 0.035 S -61.5 -48.7 6.0 0.035 0.0 PCW
PCW
 6.961
9.892
 N
N
 C8
C6
LEU D:842 C:837 6.0 0.035 S -62.3 -52.8 NA NA NA
3wgu 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 LEU A:837 A:837 2.0 0.012 S -56.8 -35.4 2.0 0.012 0.0 PC1
HOH
 6.509
8.497
 C
CD2
 O32
O
LEU D:837 C:837 3.0 0.018 S -56.2 -27.1 NA NA NA
3wgv 1 I7HD36 98.62 0.0 X-RAY
 2013-10-09 LEU A:837 A:837 2.0 0.012 S -54.1 -37.0 2.0 0.012 0.0 PC1
EFO
 6.493
9.428
 C
CD2
 O32
C3
LEU D:837 C:837 4.0 0.024 S -57.7 -16.2 NA NA NA
7d91 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 3.0 0.018 S -67.4 -51.4 3.0 0.018 0.0
7d92 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 1.0 0.006 S -64.9 -51.3 1.0 0.006 0.0 PCW
 8.074
 N
 C8
7d93 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 2.0 0.012 T -60.4 -36.5 2.0 0.012 0.0 PCW
 8.670
 N
 O2P
LEU C:837 C:837 2.0 0.012 S -61.5 -43.2 NA NA NA
7d94 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 3.0 0.018 S -60.9 -37.4 3.0 0.018 0.0 PCW
 6.493
 N
 C8
LEU D:837 C:837 3.0 0.018 S -60.5 -42.6 NA NA NA
7ddf 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 4.0 0.024 S -63.6 -57.5 4.0 0.024 0.0 PCW
 6.325
 N
 C8
LEU D:837 C:837 4.0 0.024 S -66.4 -63.0 NA NA NA
7ddh 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 4.0 0.024 S -62.5 -36.9 4.0 0.024 0.0 PCW
 6.451
 N
 C8
LEU D:837 C:837 5.0 0.029 S -63.5 -40.3 NA NA NA
7ddi 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 4.0 0.024 S -61.3 -52.3 4.0 0.024 0.0 PCW
PCW
 6.397
9.975
 N
N
 C8
O1P
LEU D:837 C:837 3.0 0.018 S -62.3 -53.3 NA NA NA
7ddj 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 2.0 0.012 S -60.1 -34.7 2.0 0.012 0.0 PCW
 8.122
 N
 C6
LEU D:837 C:837 2.0 0.012 S -59.8 -41.0 NA NA NA
7ddk 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 2.0 0.012 S -62.6 -45.6 2.0 0.012 0.0 PCW
 6.262
 N
 C8
LEU D:837 C:837 4.0 0.024 S -64.1 -47.4 NA NA NA
7ddl 1 P05024 98.13 0.0 X-RAY
 2021-01-27 LEU A:837 A:837 2.0 0.012 S -56.8 -39.0 2.0 0.012 0.0 PCW
 6.046
 N
 C8
LEU D:837 C:837 3.0 0.018 T -59.2 -44.6 NA NA NA
4xe5 1 Q08DA1 97.46 0.0 X-RAY
 2016-03-09 LEU A:842 A:842 4.0 0.024 S -71.6 -64.8 4.0 0.024 0.0
3b8e 1 P05024 98.4 0.0 X-RAY
 2007-12-18 LEU A:819 A:837 6.0 0.035 S -99.7 -65.0 6.0 0.035 0.0
LEU D:819 C:837 5.0 0.029 S -76.8 -66.4 NA NA NA
3kdp 1 P05024 98.4 0.0 X-RAY
 2010-02-16 LEU A:819 A:837 1.0 0.006 S -69.1 -56.8 1.0 0.006 0.0
LEU D:819 C:837 1.0 0.006 S -70.3 -56.3 NA NA NA
3n23 1 P05024 98.59 0.0 X-RAY
 2011-01-19 LEU A:813 A:837 19.0 0.112 S -80.3 -36.2 19.0 0.112 0.0
LEU D:813 C:837 20.0 0.118 S -80.4 -34.8 NA NA NA
2zxe 1 Q4H132 87.84 0.0 X-RAY
 2009-05-19 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0 HOH
 3.364
 CB
 O
3a3y 1 Q4H132 87.84 0.0 X-RAY
 2009-09-08 LEU A:849 A:844 3.0 0.018 S -69.6 -35.5 3.0 0.018 0.0 HOH
 3.309
 N
 O
5avq 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5avr 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.1 -37.7 0.0 0.0 0.0
5avs 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5avt 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5avu 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5avv 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5avw 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5avx 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.1 -37.7 0.0 0.0 0.0
5avy 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.1 -37.7 0.0 0.0 0.0
5avz 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5aw0 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.1 -37.8 0.0 0.0 0.0
5aw1 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5aw2 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5aw3 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.0 -37.7 0.0 0.0 0.0
5aw4 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5aw5 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5aw6 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.3 -37.6 0.0 0.0 0.0
5aw7 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.3 -37.7 0.0 0.0 0.0
5aw8 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -70.2 -37.7 0.0 0.0 0.0
5aw9 1 Q4H132 87.84 0.0 X-RAY
 2015-09-02 LEU A:849 A:844 0.0 0.0 S -65.7 -38.6 0.0 0.0 0.0 HOH
 3.348
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p05023-f1 1 P05023 100.0 0.0 LEU A:844 A:844 1.0 0.006 S -63.6 -50.7
af-p13637-f1 1 P13637 87.88 0.0 LEU A:834 A:834 1.0 0.006 S -63.7 -49.3
af-p50993-f1 1 P50993 86.71 0.0 LEU A:841 A:841 1.0 0.006 S -64.3 -48.5