Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 11734852 . G A CCDS134.1:NM_001127325.1:c.616Cgc>Tgc_NP_001120797.1:p.206R>C Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bi7 1 Q9UI95 100.0 3e-156 X-RAY
 2018-08-01 ARG A:222 A:206 86.0 0.382 -91.9 165.5 86.0 0.382 0.0
ARG C:222 C:206 49.0 0.218 -90.7 165.8 NA NA NA
ARG E:222 E:206 155.0 0.689 -83.0 360.0 NA NA NA
ARG G:222 NA:NA DO NA DO DO DO NA NA NA
6kto 1 Q9UI95 100.0 3e-156 X-RAY
 2020-04-29 ARG A:222 A:206 21.0 0.093 E -76.5 130.8 21.0 0.093 0.0
ARG B:222 B:206 101.0 0.449 -63.6 143.9 35.0 0.156 0.293 C:Q6ZNX1:0.293
6wwa 1 Q9UI95 100.0 9e-156 X-RAY
 2021-03-03 ARG A:206 A:206 66.0 0.293 -68.4 154.6 66.0 0.293 0.0
ARG B:206 D:206 24.0 0.107 E -66.0 140.0 NA NA NA
ARG C:206 C:206 109.0 0.484 -89.7 152.4 NA NA NA
ARG D:206 B:206 111.0 0.493 -86.5 157.2 74.0 0.329 0.164 F:Q86V20+Q6ZNX1:0.164
7l9p 2 Q9UI95 100.0 9e-156 EM
 2021-03-03 ARG G:206 G:206 26.0 NA -70.2 -174.3 26.0 NA NA
ARG H:206 I:206 74.0 NA -121.0 360.0 74.0 NA NA
ARG I:206 J:206 123.0 0.547 -57.6 139.4 98.0 0.436 0.111 K:Q86V20+Q6ZNX1:0.111
ARG J:206 NA:NA DO NA DO DO DO NA NA NA
6nif 1 Q9UI95,F5H018,O60673 99.52 9e-156 X-RAY
 2019-09-11 ARG A:206 A:206 21.0 0.093 -64.2 140.4 21.0 0.093 0.0 HOH
 3.500
 CD
 O
6m7a 1 Q9UI95 99.53 1e-155 X-RAY
 2021-01-27 ARG A:206 A:206 98.0 0.436 -61.1 144.7 98.0 0.436 0.0 HOH
 2.643
 O
 O
ARG C:206 B:206 91.0 0.404 -59.9 143.3 91.0 0.404 0.0 HOH
 2.971
 N
 O
6m7b 1 Q9UI95 99.53 1e-155 X-RAY
 2021-01-27 ARG A:206 A:206 100.0 0.444 -53.1 145.3 100.0 0.444 0.0 HOH
 2.754
 O
 O
ARG B:206 B:206 93.0 0.413 -62.0 136.6 93.0 0.413 0.0 HOH
 3.326
 N
 O
4gk0 1 Q9UI95 99.53 2e-155 X-RAY
 2013-03-13 ARG A:222 A:206 22.0 0.098 E -73.3 139.3 NA NA NA
ARG B:222 B:206 33.0 0.147 E -86.0 168.4 NA NA NA
4gk5 1 Q9UI95 99.53 2e-155 X-RAY
 2013-03-13 ARG A:222 A:206 26.0 0.116 E -78.5 134.4 26.0 0.116 0.0
ARG B:222 B:206 35.0 0.156 -90.9 175.2 NA NA NA
6ve5 1 Q9UI95 99.53 2e-155 X-RAY
 2021-01-13 ARG A:210 A:206 36.0 0.16 -64.4 131.3 36.0 0.16 0.0 HOH
 2.792
 O
 O
3abd 1 Q9UI95 99.53 3e-155 X-RAY
 2010-02-16 ARG A:222 A:206 25.0 0.111 E -57.2 128.7 25.0 0.111 0.0 HOH
 2.735
 NE
 O
ARG C:222 B:206 19.0 0.084 E -67.8 129.5 NA NA NA
3abe 1 Q9UI95 99.53 3e-155 X-RAY
 2010-02-16 ARG A:222 C:206 40.0 0.178 -24.1 126.8 40.0 0.178 0.0
3vu7 2 Q9UI95 99.53 3e-155 X-RAY
 2012-08-08 ARG B:222 C:206 54.0 0.24 E -47.4 146.5 54.0 0.24 0.0
5xpt 1 Q9UI95 99.53 3e-155 X-RAY
 2017-09-20 ARG A:222 A:206 28.0 0.124 -58.6 135.4 28.0 0.124 0.0 HOH
 3.532
 O
 O
5xpu 1 Q9UI95 99.53 3e-155 X-RAY
 2017-09-20 ARG A:222 NA:NA DO NA DO DO DO NA NA NA
6bc8 1 Q9UI95 99.53 3e-155 X-RAY
 2018-08-01 ARG A:222 A:206 102.0 0.453 -58.0 131.6 102.0 0.453 0.0 HOH
 5.851
 N
 O
6ws0 2 Q9UI95 99.53 3e-155 X-RAY
 2020-12-23 ARG B:222 CCC:206 22.0 0.098 -59.1 132.0 22.0 0.098 0.0
6ws5 2 Q9UI95 99.53 3e-155 X-RAY
 2020-12-23 ARG B:222 CCC:206 41.0 0.182 -56.2 144.1 41.0 0.182 0.0
6ww9 1 Q9UI95 99.52 7e-155 X-RAY
 2021-03-03 ARG A:206 A:206 50.0 0.222 -68.9 150.8 50.0 0.222 0.0
ARG C:206 B:206 65.0 0.289 -76.5 133.9 NA NA NA
6bcd 1 Q9UI95 98.58 2e-153 X-RAY
 2018-08-01 ARG A:222 A:206 88.0 0.391 -59.6 134.0 88.0 0.391 0.0 HOH
 5.988
 N
 O
4fjo 3 Q9D752 98.1 3e-152 X-RAY
 2012-08-08 ARG C:206 C:206 24.0 0.107 E -80.4 158.4 NA NA NA
6k07 1 Q9UI95 99.51 2e-150 X-RAY
 2019-12-11 ARG A:214 A:206 47.0 NA -65.8 138.0 47.0 NA NA
4ext 3 Q9UI95 100.0 7e-150 X-RAY
 2013-05-08 ARG C:201 C:206 27.0 0.12 E -59.2 135.8 27.0 0.12 0.0 HOH
 3.343
 CG
 O
6k08 1 Q9UI95 99.02 3e-149 X-RAY
 2019-12-11 ARG A:214 A:206 50.0 NA -63.4 131.1 50.0 NA NA
5o8k 1 Q9D752 96.21 5e-149 X-RAY
 2018-06-27 ARG A:206 A:206 56.0 0.249 -58.8 127.7 56.0 0.249 0.0 HOH
 2.798
 O
 O
6ekj 1 Q9D752 96.21 5e-149 X-RAY
 2018-10-10 ARG A:206 A:206 118.0 0.524 -54.0 139.7 118.0 0.524 0.0 HOH
 5.920
 N
 O
6ekl 1 Q9D752 96.21 5e-149 X-RAY
 2018-10-10 ARG A:206 A:206 111.0 0.493 -56.2 134.7 111.0 0.493 0.0
6ekm 1 Q9D752 96.21 5e-149 X-RAY
 2018-10-10 ARG A:206 A:206 74.0 0.329 -107.4 162.7 74.0 0.329 0.0 HOH
 4.152
 NH2
 O
6kea 1 P0AEX9,Q9UI95,P18011,O60673 99.5 4e-144 X-RAY
 2019-09-11 ARG A:567 A:567 48.0 0.213 E -80.4 144.7 48.0 0.213 0.0 HOH
 6.785
 C
 O
ARG B:567 B:567 45.0 0.2 -72.1 152.0 NA NA NA
ARG C:567 C:567 78.0 0.347 -69.2 162.8 NA NA NA
ARG D:567 D:567 67.0 0.298 -64.9 149.8 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ui95-f1 1 Q9UI95 100.0 6e-157 ARG A:206 A:206 26.0 0.116 E -63.0 124.8