Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 11736159 . C A CCDS134.1:NM_001127325.1:c.371cGg>cTg_NP_001120797.1:p.124R>L Homo sapiens MAD2 mitotic arrest deficient-like 2 (yeast) (MAD2L2), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
6bi7 1 Q9UI95 100.0 3e-156 X-RAY
 2018-08-01 ARG A:140 A:124 69.0 0.307 H -46.8 -37.0 69.0 0.307 0.0 HOH
 3.396
 NE
 O
ARG C:140 C:124 70.0 0.311 H -46.9 -37.7 NA NA NA
ARG E:140 E:124 67.0 0.298 H -46.5 -36.7 NA NA NA
ARG G:140 G:124 71.0 0.316 H -46.4 -36.7 NA NA NA
6kto 1 Q9UI95 100.0 3e-156 X-RAY
 2020-04-29 ARG A:140 A:124 87.0 0.387 H -58.7 -30.9 40.0 0.178 0.209 B:Q9UI95:0.209
ARG B:140 B:124 107.0 0.476 H -61.9 -43.5 38.0 0.169 0.307 A:Q9UI95:0.307
6wwa 1 Q9UI95 100.0 9e-156 X-RAY
 2021-03-03 ARG A:124 A:124 99.0 0.44 H -60.2 -35.5 18.0 0.08 0.36 D:Q9UI95:0.36
ARG B:124 D:124 90.0 0.4 H -64.1 -36.8 NA NA NA
ARG C:124 C:124 136.0 0.604 H -66.7 -46.5 NA NA NA
ARG D:124 B:124 155.0 0.689 H -79.7 -37.8 30.0 0.133 0.556 A:Q9UI95:0.556
7l9p 2 Q9UI95 100.0 9e-156 EM
 2021-03-03 ARG G:124 G:124 12.0 NA H -58.0 -43.3 7.0 NA NA J:Q9UI95:NA
ARG H:124 I:124 30.0 NA H -56.7 -53.7 23.0 NA NA I:Q9UI95:NA
ARG I:124 J:124 62.0 NA H -51.8 -43.5 46.0 NA NA H:Q9UI95:NA
ARG J:124 K:124 32.0 NA H -100.3 -13.8 21.0 NA NA G:Q9UI95:NA
6nif 1 Q9UI95,F5H018,O60673 99.52 9e-156 X-RAY
 2019-09-11 ALA A:124 A:124 10.0 0.087 H -52.2 -34.7 10.0 0.087 0.0 HOH
 5.324
 O
 O
6m7a 1 Q9UI95 99.53 1e-155 X-RAY
 2021-01-27 ALA A:124 A:124 1.0 0.009 H -57.5 -32.4 1.0 0.009 0.0 HOH
 6.079
 O
 O
ALA C:124 B:124 1.0 0.009 H -52.0 -42.4 1.0 0.009 0.0 HOH
 3.659
 CB
 O
6m7b 1 Q9UI95 99.53 1e-155 X-RAY
 2021-01-27 ALA A:124 A:124 11.0 0.096 H -55.6 -38.9 11.0 0.096 0.0 HOH
 5.476
 O
 O
ALA B:124 B:124 7.0 0.061 H -52.0 -38.0 7.0 0.061 0.0 HOH
 5.359
 O
 O
4gk0 1 Q9UI95 99.53 2e-155 X-RAY
 2013-03-13 ALA A:140 A:124 9.0 0.078 H -58.3 -30.3 NA NA NA
ALA B:140 B:124 9.0 0.078 H -48.2 -41.1 NA NA NA
4gk5 1 Q9UI95 99.53 2e-155 X-RAY
 2013-03-13 ALA A:140 A:124 9.0 0.078 H -71.5 -33.0 9.0 0.078 0.0
ALA B:140 B:124 9.0 0.078 H -53.2 -51.7 NA NA NA
6ve5 1 Q9UI95 99.53 2e-155 X-RAY
 2021-01-13 ALA A:128 A:124 11.0 0.096 H -56.6 -30.7 11.0 0.096 0.0 HOH
 4.888
 HB3
 O
3abd 1 Q9UI95 99.53 3e-155 X-RAY
 2010-02-16 ALA A:140 A:124 11.0 0.096 H -50.2 -38.3 11.0 0.096 0.0 HOH
 6.134
 O
 O
ALA C:140 B:124 11.0 0.096 H -55.7 -34.8 NA NA NA
3abe 1 Q9UI95 99.53 3e-155 X-RAY
 2010-02-16 ALA A:140 C:124 13.0 0.113 H -56.7 -25.9 13.0 0.113 0.0 HOH
 7.987
 CB
 O
3vu7 2 Q9UI95 99.53 3e-155 X-RAY
 2012-08-08 ALA B:140 C:124 9.0 0.078 H -35.9 -47.9 9.0 0.078 0.0
5xpt 1 Q9UI95 99.53 3e-155 X-RAY
 2017-09-20 ALA A:140 A:124 35.0 0.304 H -55.5 -29.7 35.0 0.304 0.0 HOH
 6.180
 N
 O
5xpu 1 Q9UI95 99.53 3e-155 X-RAY
 2017-09-20 ALA A:140 A:124 28.0 0.243 H -58.2 -44.7 28.0 0.243 0.0 HOH
 5.325
 O
 O
6bc8 1 Q9UI95 99.53 3e-155 X-RAY
 2018-08-01 ALA A:140 A:124 7.0 0.061 H -53.9 -37.5 7.0 0.061 0.0 HOH
 3.748
 CB
 O
6ws0 2 Q9UI95 99.53 3e-155 X-RAY
 2020-12-23 ALA B:140 CCC:124 10.0 0.087 H -59.3 -36.6 10.0 0.087 0.0
6ws5 2 Q9UI95 99.53 3e-155 X-RAY
 2020-12-23 ALA B:140 CCC:124 8.0 0.07 H -68.9 -42.6 8.0 0.07 0.0
6ww9 1 Q9UI95 99.52 7e-155 X-RAY
 2021-03-03 ALA A:124 A:124 8.0 0.07 H -63.0 -29.9 8.0 0.07 0.0
ALA C:124 B:124 10.0 0.087 H -63.6 -35.0 NA NA NA
6bcd 1 Q9UI95 98.58 2e-153 X-RAY
 2018-08-01 ALA A:140 A:124 8.0 0.07 H -54.0 -36.9 8.0 0.07 0.0 HOH
 3.633
 CB
 O
4fjo 3 Q9D752 98.1 3e-152 X-RAY
 2012-08-08 ALA C:124 C:124 11.0 0.096 H -62.1 -37.7 NA NA NA
6k07 1 Q9UI95 99.51 2e-150 X-RAY
 2019-12-11 ALA A:132 A:124 10.0 0.087 H -52.0 -36.0 10.0 0.087 0.0 HOH
 8.293
 N
 O
4ext 3 Q9UI95 100.0 7e-150 X-RAY
 2013-05-08 ARG C:119 C:124 55.0 0.244 H -57.5 -36.7 55.0 0.244 0.0 HOH
 3.491
 NH1
 O
6k08 1 Q9UI95 99.02 3e-149 X-RAY
 2019-12-11 ALA A:132 A:124 9.0 0.078 H -61.4 -36.3 9.0 0.078 0.0 HOH
 6.599
 CB
 O
5o8k 1 Q9D752 96.21 5e-149 X-RAY
 2018-06-27 ARG A:124 A:124 66.0 0.293 H -60.8 -34.3 66.0 0.293 0.0 HOH
 5.681
 O
 O
6ekj 1 Q9D752 96.21 5e-149 X-RAY
 2018-10-10 ARG A:124 A:124 66.0 0.293 H -58.4 -41.8 66.0 0.293 0.0 HOH
 5.076
 O
 O
6ekl 1 Q9D752 96.21 5e-149 X-RAY
 2018-10-10 ARG A:124 A:124 63.0 0.28 H -56.8 -39.7 63.0 0.28 0.0 HOH
 5.047
 O
 O
6ekm 1 Q9D752 96.21 5e-149 X-RAY
 2018-10-10 ARG A:124 A:124 62.0 0.276 H -43.6 -37.5 62.0 0.276 0.0
6kea 1 P0AEX9,Q9UI95,P18011,O60673 99.5 4e-144 X-RAY
 2019-09-11 ALA A:485 A:485 9.0 0.078 H -54.9 -36.7 9.0 0.078 0.0 HOH
 8.071
 O
 O
ALA B:485 B:485 9.0 0.078 H -57.4 -42.8 NA NA NA
ALA C:485 C:485 9.0 0.078 H -62.8 -34.5 NA NA NA
ALA D:485 D:485 10.0 0.087 H -51.4 -39.1 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-q9ui95-f1 1 Q9UI95 100.0 6e-157 ARG A:124 A:124 56.0 0.249 H -50.7 -39.3