Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160097429 . G A CCDS1196.1:NM_000702.3:c.836cGg>cAg_NP_000693.1:p.279R>Q Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 GLN A:279 A:279 122.0 0.678 -72.1 133.8 122.0 0.678 0.0 MG
 8.038
 N
 MG
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLN A:274 A:274 104.0 0.578 -133.4 98.2 104.0 0.578 0.0 NA
HOH
 9.218
5.533
 N
OE1
 NA
O
GLN D:274 C:274 118.0 0.656 -103.4 112.3 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 GLN A:274 A:274 105.0 0.583 -134.9 97.9 105.0 0.583 0.0 NA
EFO
HOH
 9.049
3.806
6.159
 N
OE1
O
 NA
C51
O
GLN D:274 C:274 118.0 0.656 -109.6 102.5 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 GLN A:279 A:274 187.0 1.0 -122.1 152.9 187.0 1.0 0.0
GLN D:279 C:274 180.0 1.0 -122.6 152.4 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 GLN A:279 A:274 109.0 0.606 -74.4 123.6 109.0 0.606 0.0 MG
17F
 8.420
9.726
 N
OE1
 MG
O5
GLN D:279 C:274 110.0 0.611 -73.4 123.7 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLN A:279 A:274 94.0 0.522 -99.3 126.6 94.0 0.522 0.0 K
 8.849
 N
 K
GLN D:279 C:274 98.0 0.544 -98.7 127.2 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 GLN A:279 A:274 110.0 0.611 -78.5 125.1 110.0 0.611 0.0 MG
 8.214
 N
 MG
GLN D:279 C:274 114.0 0.633 -77.6 125.1 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 GLN A:279 A:274 116.0 0.644 -110.0 118.6 116.0 0.644 0.0 NA
PCW
 7.905
7.257
 N
OE1
 NA
C6
GLN D:279 C:274 110.0 0.611 -112.0 118.7 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 121.0 0.672 -94.6 122.0 121.0 0.672 0.0 MG
HOH
 8.239
8.579
 N
N
 MG
O
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 119.0 0.661 -98.6 118.6 119.0 0.661 0.0 MG
HOH
 8.267
8.896
 N
N
 MG
O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 106.0 0.589 -122.6 115.7 106.0 0.589 0.0 NA
 7.422
 N
 NA
GLN C:274 C:274 110.0 0.611 -123.5 116.5 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 101.0 0.561 -120.5 115.6 101.0 0.561 0.0 NA
 7.596
 N
 NA
GLN D:274 C:274 105.0 0.583 -122.9 115.9 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 113.0 0.628 -105.1 119.5 113.0 0.628 0.0 NA
 7.471
 N
 NA
GLN D:274 C:274 116.0 0.644 -105.4 120.3 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 109.0 0.606 -128.3 118.2 109.0 0.606 0.0 NA
PCW
 7.610
7.979
 N
OE1
 NA
C6
GLN D:274 C:274 112.0 0.622 -129.7 118.1 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 106.0 0.589 -110.9 121.4 106.0 0.589 0.0 NA
PCW
 7.558
6.312
 N
OE1
 NA
C6
GLN D:274 C:274 110.0 0.611 -112.6 121.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 106.0 0.589 -123.1 115.2 106.0 0.589 0.0 NA
PCW
 7.201
9.291
 N
OE1
 NA
C6
GLN D:274 C:274 112.0 0.622 -124.4 116.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 109.0 0.606 -115.2 121.0 109.0 0.606 0.0 NA
 7.904
 N
 NA
GLN D:274 C:274 115.0 0.639 -116.8 119.6 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 GLN A:274 A:274 102.0 0.567 -121.6 116.1 102.0 0.567 0.0 NA
PCW
 7.446
7.568
 N
OE1
 NA
C6
GLN D:274 C:274 106.0 0.589 -123.3 115.6 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 GLN A:256 A:274 142.0 0.789 -90.8 118.9 142.0 0.789 0.0 RB
 8.228
 N
 RB
GLN D:256 C:274 135.0 0.75 -90.7 121.1 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 GLN A:256 A:274 106.0 0.589 -52.9 127.8 106.0 0.589 0.0 RB
 8.112
 O
 RB
GLN D:256 C:274 118.0 0.656 -50.3 126.6 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 GLN A:250 A:274 156.0 0.867 -92.0 131.7 156.0 0.867 0.0
GLN D:250 C:274 157.0 0.872 -91.3 132.1 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ARG A:286 A:281 161.0 0.716 -82.6 138.9 161.0 0.716 0.0 K
HOH
 9.107
3.451
 O
CA
 K
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ARG A:286 A:281 149.0 0.662 -80.2 132.2 149.0 0.662 0.0 K
 8.403
 O
 K
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.7 139.0 161.0 0.716 0.0 K
TL
 9.107
9.107
 O
O
 K
TL
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.5 138.9 161.0 0.716 0.0 K
TL
 9.108
9.108
 O
O
 K
TL
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.6 138.9 161.0 0.716 0.0 K
TL
 9.108
9.108
 O
O
 K
TL
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.5 138.9 161.0 0.716 0.0 K
TL
 9.107
9.107
 O
O
 K
TL
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.5 138.9 161.0 0.716 0.0 K
TL
 9.108
9.108
 O
O
 K
TL
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.7 138.9 161.0 0.716 0.0 K
TL
 9.107
9.107
 O
O
 K
TL
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.6 138.8 161.0 0.716 0.0 K
TL
 9.107
9.107
 O
O
 K
TL
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.6 138.9 161.0 0.716 0.0 K
TL
 9.106
9.106
 O
O
 K
TL
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.5 138.9 161.0 0.716 0.0 K
TL
 9.108
9.108
 O
O
 K
TL
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.5 138.9 161.0 0.716 0.0 K
TL
 9.108
9.108
 O
O
 K
TL
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.4 138.9 161.0 0.716 0.0 K
TL
 9.108
9.108
 O
O
 K
TL
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.6 139.0 161.0 0.716 0.0 K
TL
 9.107
9.107
 O
O
 K
TL
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.6 138.9 161.0 0.716 0.0 K
TL
 9.108
9.108
 O
O
 K
TL
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.5 138.9 161.0 0.716 0.0 K
TL
 9.107
9.107
 O
O
 K
TL
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 160.0 0.711 -82.5 138.9 160.0 0.711 0.0 K
RB
 9.108
9.108
 O
O
 K
RB
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.5 138.9 161.0 0.716 0.0 K
RB
 9.107
9.107
 O
O
 K
RB
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.6 138.9 161.0 0.716 0.0 K
RB
 9.109
9.109
 O
O
 K
RB
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.7 138.9 161.0 0.716 0.0 K
RB
 9.109
9.109
 O
O
 K
RB
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 161.0 0.716 -82.5 138.9 161.0 0.716 0.0 RB
 9.107
 O
 RB
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ARG A:286 A:281 158.0 0.702 -82.7 137.9 158.0 0.702 0.0 K
HOH
 9.299
3.585
 O
CA
 K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ARG A:279 A:279 159.0 0.707 -72.6 130.6
af-p13637-f1 1 P13637 88.37 0.0 LYS A:271 A:271 122.0 0.61 -71.1 132.7
af-p05023-f1 1 P05023 86.71 0.0 GLN A:281 A:281 123.0 0.683 -87.4 134.8
af-q13733-f1 1 Q13733 80.48 0.0 GLN A:289 A:289 127.0 0.706 -74.0 131.6