Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160097450 . T A CCDS1196.1:NM_000702.3:c.857aTt>aAt_NP_000693.1:p.286I>N Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ILE A:286 A:286 35.0 0.2 H -60.6 -41.3 35.0 0.2 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ILE A:281 A:281 21.0 0.12 H -61.3 -49.9 21.0 0.12 0.0 PC1
HOH
 7.410
3.607
 O
CG2
 O32
O
ILE D:281 C:281 16.0 0.091 H -54.3 -60.9 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ILE A:281 A:281 21.0 0.12 H -55.7 -51.4 21.0 0.12 0.0 PC1
EFO
 7.471
4.282
 O
CG2
 O32
C3
ILE D:281 C:281 19.0 0.109 H -50.8 -58.8 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ILE A:286 A:281 18.0 0.103 H -57.9 -52.4 18.0 0.103 0.0
ILE D:286 C:281 18.0 0.103 H -58.3 -52.4 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ILE A:286 A:281 28.0 0.16 H -68.7 -37.1 28.0 0.16 0.0 17F
 8.091
 O
 O5
ILE D:286 C:281 28.0 0.16 H -68.7 -37.6 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ILE A:286 A:281 39.0 0.223 H -58.4 -38.7 39.0 0.223 0.0
ILE D:286 C:281 38.0 0.217 H -58.2 -38.2 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ILE A:286 A:281 33.0 0.189 H -67.8 -39.4 33.0 0.189 0.0 17F
 8.456
 O
 O4
ILE D:286 C:281 34.0 0.194 H -67.4 -39.3 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ILE A:286 A:281 31.0 0.177 H -63.1 -44.0 31.0 0.177 0.0 PCW
 8.356
 O
 O2P
ILE D:286 C:281 30.0 0.171 H -62.9 -41.8 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 35.0 0.2 H -60.8 -40.3 35.0 0.2 0.0 PCW
 9.423
 O
 O2P
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 30.0 0.171 H -62.2 -40.1 30.0 0.171 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 29.0 0.166 H -64.2 -39.0 29.0 0.166 0.0
ILE C:281 C:281 30.0 0.171 H -62.9 -36.4 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 32.0 0.183 H -64.1 -38.3 32.0 0.183 0.0
ILE D:281 C:281 29.0 0.166 H -63.4 -35.6 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 32.0 0.183 H -64.8 -43.7 32.0 0.183 0.0
ILE D:281 C:281 24.0 0.137 H -63.1 -42.3 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 33.0 0.189 H -67.0 -42.5 33.0 0.189 0.0 PCW
 8.141
 O
 O2P
ILE D:281 C:281 31.0 0.177 H -66.8 -41.5 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 31.0 0.177 H -62.4 -42.4 31.0 0.177 0.0 PCW
 8.010
 O
 O2P
ILE D:281 C:281 31.0 0.177 H -62.2 -41.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 34.0 0.194 H -64.7 -37.5 34.0 0.194 0.0 PCW
 9.583
 O
 O2P
ILE D:281 C:281 32.0 0.183 H -63.8 -34.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 28.0 0.16 H -63.8 -40.7 28.0 0.16 0.0
ILE D:281 C:281 26.0 0.149 H -63.3 -39.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:281 A:281 30.0 0.171 H -64.7 -36.9 30.0 0.171 0.0 PCW
 8.883
 O
 O2P
ILE D:281 C:281 27.0 0.154 H -64.6 -33.9 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ILE A:263 A:281 18.0 0.103 H -69.1 4.7 18.0 0.103 0.0
ILE D:263 C:281 15.0 0.086 H -82.5 -5.1 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ILE A:263 A:281 21.0 0.12 H -43.8 -64.4 21.0 0.12 0.0
ILE D:263 C:281 20.0 0.114 H -57.6 -53.6 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ILE A:257 A:281 40.0 0.229 H -54.8 -60.5 40.0 0.229 0.0
ILE D:257 C:281 41.0 0.234 H -54.7 -60.9 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ILE A:293 A:288 18.0 0.103 H -57.7 -53.2 18.0 0.103 0.0 HOH
 4.588
 CG2
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ILE A:293 A:288 30.0 0.171 H -72.3 -52.1 30.0 0.171 0.0 HOH
 3.367
 CD1
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.8 -53.2 18.0 0.103 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.2 18.0 0.103 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.2 18.0 0.103 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.8 -53.2 18.0 0.103 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.2 18.0 0.103 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 17.0 0.097 H -57.8 -53.1 17.0 0.097 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.8 -53.1 18.0 0.103 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 17.0 0.097 H -57.7 -53.2 17.0 0.097 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 17.0 0.097 H -57.7 -53.2 17.0 0.097 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.2 18.0 0.103 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.8 -53.1 18.0 0.103 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.9 -53.1 18.0 0.103 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.2 18.0 0.103 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.2 18.0 0.103 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.3 18.0 0.103 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 17.0 0.097 H -57.8 -53.2 17.0 0.097 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.2 18.0 0.103 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.8 -53.2 18.0 0.103 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 18.0 0.103 H -57.7 -53.3 18.0 0.103 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:293 A:288 15.0 0.086 H -58.1 -53.1 15.0 0.086 0.0 HOH
 4.336
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ILE A:286 A:286 31.0 0.177 H -63.0 -42.5
af-p13637-f1 1 P13637 88.37 0.0 ILE A:278 A:278 30.0 0.171 H -63.3 -42.6
af-p05023-f1 1 P05023 86.71 0.0 ILE A:288 A:288 32.0 0.183 H -64.0 -42.4
af-q13733-f1 1 Q13733 80.48 0.0 ILE A:296 A:296 31.0 0.177 H -63.5 -42.0