Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160097552 . T A CCDS1196.1:NM_000702.3:c.959aTc>aAc_NP_000693.1:p.320I>N Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ILE A:320 A:320 31.0 0.177 H -52.7 -44.3 31.0 0.177 0.0 OBN
 3.900
 CG2
 O11
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ILE A:315 A:315 2.0 0.011 H -81.1 -23.9 2.0 0.011 0.0
ILE D:315 C:315 3.0 0.017 H -68.9 -36.5 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ILE A:315 A:315 2.0 0.011 H -75.2 -35.5 2.0 0.011 0.0
ILE D:315 C:315 3.0 0.017 H -64.7 -37.4 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ILE A:320 A:315 11.0 0.063 H -68.6 -34.0 11.0 0.063 0.0
ILE D:320 C:315 11.0 0.063 H -68.6 -33.6 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ILE A:320 A:315 28.0 0.16 H -59.4 -40.8 28.0 0.16 0.0 OBN
 3.330
 CG2
 O11
ILE D:320 C:315 27.0 0.154 H -59.9 -40.4 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ILE A:320 A:315 20.0 0.114 H -55.1 -38.1 20.0 0.114 0.0 BUF
 3.582
 CG2
 C2
ILE D:320 C:315 23.0 0.131 H -55.0 -38.3 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ILE A:320 A:315 24.0 0.137 H -56.1 -38.0 24.0 0.137 0.0 DGX
 4.008
 CG2
 C1
ILE D:320 C:315 24.0 0.137 H -56.1 -38.1 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ILE A:320 A:315 28.0 0.16 H -66.1 -34.3 28.0 0.16 0.0 JEO
 4.152
 CG2
 CAT
ILE D:320 C:315 26.0 0.149 H -65.2 -35.8 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 16.0 0.091 H -59.5 -43.4 16.0 0.091 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 30.0 0.171 H -59.5 -42.8 30.0 0.171 0.0 H0C
 3.212
 CG2
 O4
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 22.0 0.126 H -66.9 -32.4 22.0 0.126 0.0 H0C
 3.238
 CG2
 O4
ILE C:315 C:315 34.0 0.194 H -65.3 -32.7 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 22.0 0.126 H -66.1 -33.2 22.0 0.126 0.0 BUF
 4.055
 CG2
 C1
ILE D:315 C:315 18.0 0.103 H -65.6 -33.8 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 19.0 0.109 H -66.0 -34.6 19.0 0.109 0.0
ILE D:315 C:315 21.0 0.12 H -65.5 -36.1 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 23.0 0.131 H -61.5 -39.6 23.0 0.131 0.0 DGX
 4.127
 CG2
 C1
ILE D:315 C:315 20.0 0.114 H -61.3 -39.9 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 17.0 0.097 H -60.8 -42.6 17.0 0.097 0.0 F9R
 4.064
 CG2
 C1
ILE D:315 C:315 20.0 0.114 H -59.7 -43.0 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 22.0 0.126 H -66.5 -32.5 22.0 0.126 0.0 OBN
 3.157
 CG2
 O11
ILE D:315 C:315 25.0 0.143 H -66.5 -33.3 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 20.0 0.114 H -65.1 -35.1 20.0 0.114 0.0 E4R
 4.523
 CG2
 C11
ILE D:315 C:315 20.0 0.114 H -64.5 -36.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ILE A:315 A:315 24.0 0.137 H -66.1 -34.1 24.0 0.137 0.0 BUF
 4.496
 CG2
 C1
ILE D:315 C:315 26.0 0.149 H -65.5 -33.9 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ILE A:297 A:315 52.0 0.297 H -63.7 -26.6 52.0 0.297 0.0
ILE D:297 C:315 52.0 0.297 H -56.1 -27.9 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ILE A:297 A:315 56.0 0.32 H -87.4 -23.8 56.0 0.32 0.0
ILE D:297 C:315 72.0 0.411 H -55.7 -26.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ILE A:291 A:315 51.0 0.291 H -66.7 -10.0 51.0 0.291 0.0 OBN
 4.244
 O
 O11
ILE D:291 C:315 50.0 0.286 H -66.5 -10.1 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ILE A:327 A:322 54.0 0.309 H -62.4 -40.3 54.0 0.309 0.0 HOH
 3.197
 O
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ILE A:327 A:322 70.0 0.4 H -62.0 -22.7 70.0 0.4 0.0 OBN
 3.765
 O
 O11
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.4 -40.3 54.0 0.309 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.4 -40.3 54.0 0.309 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.5 -40.3 54.0 0.309 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.4 -40.3 55.0 0.314 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.4 -40.3 55.0 0.314 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.3 -40.4 55.0 0.314 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.4 -40.3 54.0 0.309 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.3 -40.3 55.0 0.314 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.3 -40.3 55.0 0.314 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.4 -40.3 55.0 0.314 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.3 -40.4 55.0 0.314 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.3 -40.4 55.0 0.314 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.3 -40.3 54.0 0.309 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 55.0 0.314 H -62.3 -40.4 55.0 0.314 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.2 -40.4 54.0 0.309 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.3 -40.3 54.0 0.309 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.3 -40.4 54.0 0.309 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.3 -40.3 54.0 0.309 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 54.0 0.309 H -62.4 -40.4 54.0 0.309 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ILE A:327 A:322 52.0 0.297 H -56.8 -42.0 52.0 0.297 0.0 HOH
 2.910
 O
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ILE A:320 A:320 45.0 0.257 H -61.3 -41.0
af-p13637-f1 1 P13637 88.37 0.0 ILE A:312 A:312 46.0 0.263 H -62.0 -42.0
af-p05023-f1 1 P05023 86.71 0.0 ILE A:322 A:322 39.0 0.223 H -61.7 -42.1
af-q13733-f1 1 Q13733 80.48 0.0 ILE A:330 A:330 44.0 0.251 H -61.8 -40.6