Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160098457 . A C CCDS1196.1:NM_000702.3:c.1033Aca>Cca_NP_000693.1:p.345T>P Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 THR A:345 A:345 5.0 0.036 H -59.1 -39.3 5.0 0.036 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:340 A:340 2.0 0.014 H -61.1 -38.9 2.0 0.014 0.0 PC1
 9.520
 N
 O12
THR D:340 C:340 1.0 0.007 H -51.3 -44.0 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:340 A:340 2.0 0.014 H -55.8 -31.9 2.0 0.014 0.0 PC1
 9.618
 N
 O12
THR D:340 C:340 3.0 0.021 H -51.8 -37.7 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 THR A:345 A:340 4.0 0.029 H -52.9 -37.5 4.0 0.029 0.0
THR D:345 C:340 4.0 0.029 H -53.5 -36.9 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 THR A:345 A:340 7.0 0.05 H -54.8 -44.1 7.0 0.05 0.0
THR D:345 C:340 6.0 0.043 H -55.0 -44.7 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:345 A:340 2.0 0.014 H -54.7 -42.7 2.0 0.014 0.0
THR D:345 C:340 2.0 0.014 H -55.7 -43.0 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:345 A:340 10.0 0.071 H -56.6 -44.9 10.0 0.071 0.0
THR D:345 C:340 10.0 0.071 H -56.5 -45.0 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 THR A:345 A:340 1.0 0.007 H -65.1 -34.6 1.0 0.007 0.0 PCW
 9.419
 N
 O2P
THR D:345 C:340 1.0 0.007 H -65.3 -36.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 2.0 0.014 H -62.5 -34.0 2.0 0.014 0.0 PCW
PCW
 8.429
8.052
 N
N
 O1P
O2P
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 1.0 0.007 H -63.7 -39.8 1.0 0.007 0.0 PCW
 8.663
 N
 O2P
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 2.0 0.014 H -66.9 -35.2 2.0 0.014 0.0 PCW
 9.199
 N
 O1P
THR C:340 C:340 2.0 0.014 H -66.0 -35.9 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 2.0 0.014 H -65.8 -35.1 2.0 0.014 0.0 PCW
 7.633
 N
 O2P
THR D:340 C:340 1.0 0.007 H -65.5 -36.4 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 5.0 0.036 H -72.9 -37.7 5.0 0.036 0.0 PCW
 9.443
 N
 O2P
THR D:340 C:340 4.0 0.029 H -73.7 -37.6 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 2.0 0.014 H -64.8 -30.2 2.0 0.014 0.0 PCW
 9.436
 N
 O2P
THR D:340 C:340 1.0 0.007 H -64.8 -30.0 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 2.0 0.014 H -62.3 -38.8 2.0 0.014 0.0 PCW
 8.917
 N
 O2P
THR D:340 C:340 3.0 0.021 H -62.4 -39.0 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 2.0 0.014 H -66.3 -35.8 2.0 0.014 0.0
THR D:340 C:340 2.0 0.014 H -65.4 -36.1 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 1.0 0.007 H -62.8 -36.7 1.0 0.007 0.0
THR D:340 C:340 2.0 0.014 H -63.1 -36.7 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:340 A:340 1.0 0.007 H -65.6 -37.3 1.0 0.007 0.0 PCW
 9.879
 N
 O2P
THR D:340 C:340 1.0 0.007 H -65.3 -36.8 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 THR A:322 A:340 1.0 0.007 H -58.4 -0.9 1.0 0.007 0.0
THR D:322 C:340 1.0 0.007 H -67.2 -15.8 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 THR A:322 A:340 1.0 0.007 H -53.8 -23.4 1.0 0.007 0.0
THR D:322 C:340 0.0 0.0 H -47.6 -6.9 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:316 A:340 0.0 0.0 H -49.2 -42.5 0.0 0.0 0.0
THR D:316 C:340 0.0 0.0 H -50.5 -42.7 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 THR A:352 A:347 2.0 0.014 H -68.3 -39.4 2.0 0.014 0.0 HOH
 8.441
 CG2
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 THR A:352 A:347 1.0 0.007 H -70.3 -48.1 1.0 0.007 0.0 HOH
 8.067
 CG2
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.4 2.0 0.014 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.4 2.0 0.014 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.5 2.0 0.014 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.3 2.0 0.014 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.4 2.0 0.014 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.4 2.0 0.014 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.3 2.0 0.014 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.4 2.0 0.014 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.5 2.0 0.014 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.4 2.0 0.014 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.3 2.0 0.014 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.3 2.0 0.014 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.4 2.0 0.014 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.3 2.0 0.014 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.4 2.0 0.014 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.4 2.0 0.014 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.4 2.0 0.014 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.4 -39.4 2.0 0.014 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 2.0 0.014 H -68.3 -39.4 2.0 0.014 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:352 A:347 0.0 0.0 H -66.7 -39.0 0.0 0.0 0.0 HOH
 8.422
 CG2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 THR A:345 A:345 2.0 0.014 H -66.8 -43.4
af-p13637-f1 1 P13637 88.37 0.0 THR A:337 A:337 3.0 0.021 H -67.6 -43.2
af-p05023-f1 1 P05023 86.71 0.0 THR A:347 A:347 2.0 0.014 H -67.7 -43.0
af-q13733-f1 1 Q13733 80.48 0.0 THR A:355 A:355 2.0 0.014 H -67.3 -43.2