Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160098548 . A C CCDS1196.1:NM_000702.3:c.1124aAg>aCg_NP_000693.1:p.375K>T Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 LYS A:375 A:375 0.0 0.0 I -90.6 -73.5 0.0 0.0 0.0 MG
HOH
 4.734
5.759
 C
N
 MG
O
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LYS A:370 A:370 2.0 0.01 I -94.2 -61.2 2.0 0.01 0.0 MG
ALF
MG
ADP
HOH
 8.679
2.761
5.674
4.481
5.621
 C
N
N
NZ
C
 MG
F1
MG
O3B
O
LYS D:370 C:370 2.0 0.01 I -96.3 -63.9 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LYS A:370 A:370 2.0 0.01 I -92.4 -73.3 2.0 0.01 0.0 MG
ALF
MG
ADP
HOH
 8.252
3.182
5.180
4.749
6.714
 C
N
C
CB
C
 MG
F1
MG
O3B
O
LYS D:370 C:370 2.0 0.01 I -89.6 -73.2 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 LYS A:375 A:370 0.0 0.0 I -92.9 -71.3 0.0 0.0 0.0 ADP
ALF
MG
 5.759
3.444
4.924
 N
CB
C
 O3B
F2
MG
LYS D:375 C:370 0.0 0.0 I -92.3 -71.6 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 LYS A:375 A:370 0.0 0.0 I -88.8 -73.2 0.0 0.0 0.0 MG
 4.071
 C
 MG
LYS D:375 C:370 0.0 0.0 I -87.9 -73.2 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LYS A:375 A:370 0.0 0.0 T -90.1 -74.7 0.0 0.0 0.0 MG
 4.458
 C
 MG
LYS D:375 C:370 0.0 0.0 I -90.4 -74.3 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LYS A:375 A:370 0.0 0.0 I -88.5 -70.2 0.0 0.0 0.0 MG
 4.377
 C
 MG
LYS D:375 C:370 0.0 0.0 I -88.8 -69.9 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 LYS A:375 A:370 0.0 0.0 I -77.5 -71.4 0.0 0.0 0.0 MG
HOH
 5.495
6.603
 C
N
 MG
O
LYS D:375 C:370 0.0 0.0 I -80.3 -72.5 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -86.0 -65.5 0.0 0.0 0.0 MG
HOH
 5.262
6.304
 C
N
 MG
O
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -90.0 -62.0 0.0 0.0 0.0 MG
HOH
 5.213
6.167
 C
N
 MG
O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -86.6 -66.9 0.0 0.0 0.0 MG
HOH
 5.346
6.377
 C
N
 MG
O
LYS C:370 C:370 0.0 0.0 I -85.9 -67.1 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -85.6 -67.4 0.0 0.0 0.0 MG
HOH
 5.309
6.277
 C
N
 MG
O
LYS D:370 C:370 0.0 0.0 I -89.5 -66.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -86.3 -71.3 0.0 0.0 0.0 MG
HOH
 5.205
6.033
 C
N
 MG
O
LYS D:370 C:370 0.0 0.0 I -94.7 -69.0 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -80.5 -71.3 0.0 0.0 0.0 MG
HOH
 5.352
6.446
 C
N
 MG
O
LYS D:370 C:370 0.0 0.0 I -84.6 -71.2 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -82.1 -74.7 0.0 0.0 0.0 MG
HOH
 5.431
6.425
 C
N
 MG
O
LYS D:370 C:370 0.0 0.0 I -75.1 -76.7 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -85.9 -66.9 0.0 0.0 0.0 MG
HOH
 5.275
6.324
 C
N
 MG
O
LYS D:370 C:370 0.0 0.0 I -87.6 -66.5 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -76.2 -68.7 0.0 0.0 0.0 MG
HOH
 5.394
6.303
 C
N
 MG
O
LYS D:370 C:370 0.0 0.0 I -80.9 -68.6 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:370 A:370 0.0 0.0 I -86.5 -65.7 0.0 0.0 0.0 MG
HOH
 5.380
6.195
 C
N
 MG
O
LYS D:370 C:370 0.0 0.0 I -85.4 -65.3 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 LYS A:352 A:370 0.0 0.0 I -57.2 -73.9 0.0 0.0 0.0 MG
MF4
 5.591
3.210
 C
N
 MG
F4
LYS D:352 C:370 1.0 0.005 I -57.1 -74.1 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 LYS A:352 A:370 2.0 0.01 I -78.5 -64.8 2.0 0.01 0.0 MF4
MG
 3.327
5.414
 N
C
 F4
MG
LYS D:352 C:370 1.0 0.005 I -77.7 -65.4 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LYS A:346 A:370 0.0 0.0 I -93.7 -62.2 0.0 0.0 0.0 MG
 5.303
 N
 MG
LYS D:346 C:370 0.0 0.0 I -93.2 -63.0 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 LYS A:382 A:377 1.0 0.005 I -98.6 -62.9 1.0 0.005 0.0 MF4
MG
HOH
 2.637
4.778
2.701
 N
C
NZ
 F4
MG
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 LYS A:382 A:377 1.0 0.005 I -86.9 -67.4 1.0 0.005 0.0 MF4
MG
HOH
 2.627
4.916
3.388
 N
C
NZ
 F4
MG
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -63.0 1.0 0.005 0.0 MF4
MG
 2.638
4.777
 N
C
 F4
MG
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -63.0 1.0 0.005 0.0 MF4
MG
 2.637
4.779
 N
C
 F4
MG
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -63.0 1.0 0.005 0.0 MF4
MG
 2.638
4.777
 N
C
 F4
MG
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -62.9 1.0 0.005 0.0 MF4
MG
 2.637
4.777
 N
C
 F4
MG
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.7 -62.8 1.0 0.005 0.0 MF4
MG
 2.637
4.779
 N
C
 F4
MG
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -62.9 1.0 0.005 0.0 MF4
MG
 2.638
4.779
 N
C
 F4
MG
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -63.0 1.0 0.005 0.0 MF4
MG
 2.636
4.777
 N
C
 F4
MG
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -62.9 1.0 0.005 0.0 MF4
MG
 2.636
4.779
 N
C
 F4
MG
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -63.0 1.0 0.005 0.0 MF4
MG
 2.638
4.778
 N
C
 F4
MG
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -63.0 1.0 0.005 0.0 MF4
MG
 2.637
4.777
 N
C
 F4
MG
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -63.0 1.0 0.005 0.0 MF4
MG
 2.636
4.777
 N
C
 F4
MG
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -62.9 1.0 0.005 0.0 MF4
MG
 2.637
4.779
 N
C
 F4
MG
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.5 -63.0 1.0 0.005 0.0 MF4
MG
 2.637
4.778
 N
C
 F4
MG
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -62.8 1.0 0.005 0.0 MF4
MG
 2.636
4.778
 N
C
 F4
MG
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -62.9 1.0 0.005 0.0 MF4
MG
 2.637
4.778
 N
C
 F4
MG
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -62.9 1.0 0.005 0.0 MF4
MG
 2.636
4.777
 N
C
 F4
MG
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -62.9 1.0 0.005 0.0 MF4
MG
 2.637
4.777
 N
C
 F4
MG
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -63.0 1.0 0.005 0.0 MF4
MG
 2.637
4.777
 N
C
 F4
MG
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 I -98.6 -62.9 1.0 0.005 0.0 MF4
MG
 2.636
4.778
 N
C
 F4
MG
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 LYS A:382 A:377 1.0 0.005 -95.3 -66.9 1.0 0.005 0.0 MF4
MG
HOH
 2.639
5.072
2.829
 N
C
NZ
 F4
MG
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 LYS A:375 A:375 4.0 0.02 I -89.2 -61.4
af-p13637-f1 1 P13637 88.37 0.0 LYS A:367 A:367 5.0 0.025 I -90.0 -59.7
af-p05023-f1 1 P05023 86.71 0.0 LYS A:377 A:377 5.0 0.025 I -85.5 -58.2
af-q13733-f1 1 Q13733 80.48 0.0 LYS A:385 A:385 4.0 0.02 I -88.3 -63.4