Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160099904 . G A CCDS1196.1:NM_000702.3:c.1474Gag>Aag_NP_000693.1:p.492E>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 LYS A:492 A:492 70.0 0.35 -73.7 -179.5 70.0 0.35 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LYS A:487 A:487 74.0 0.37 E -67.2 136.7 74.0 0.37 0.0 HOH
 8.256
 NZ
 O
LYS D:487 C:487 78.0 0.39 -75.7 154.2 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 LYS A:487 A:487 75.0 0.375 E -72.3 136.1 75.0 0.375 0.0 HOH
 8.355
 NZ
 O
LYS D:487 C:487 86.0 0.43 -74.5 138.9 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 LYS A:492 A:487 98.0 0.49 -70.9 -179.6 98.0 0.49 0.0
LYS D:492 C:487 99.0 0.495 -70.9 -179.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 LYS A:492 A:487 68.0 0.34 -87.3 167.9 68.0 0.34 0.0
LYS D:492 C:487 66.0 0.33 -87.9 168.0 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LYS A:492 A:487 65.0 0.325 -78.4 -177.3 65.0 0.325 0.0
LYS D:492 C:487 69.0 0.345 -78.5 -176.6 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 LYS A:492 A:487 68.0 0.34 -83.0 -179.6 68.0 0.34 0.0
LYS D:492 C:487 69.0 0.345 -83.0 -179.6 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 LYS A:492 A:487 57.0 0.285 -82.9 147.7 57.0 0.285 0.0
LYS D:492 C:487 59.0 0.295 -83.0 147.1 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 50.0 0.25 E -83.9 154.0 50.0 0.25 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 51.0 0.255 -90.7 163.2 51.0 0.255 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 63.0 0.315 -76.8 155.5 63.0 0.315 0.0
LYS C:487 C:487 67.0 0.335 -76.8 155.7 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 63.0 0.315 -76.5 155.8 63.0 0.315 0.0
LYS D:487 C:487 67.0 0.335 -76.9 155.0 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 63.0 0.315 -77.4 149.9 63.0 0.315 0.0
LYS D:487 C:487 63.0 0.315 -79.2 148.9 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 65.0 0.325 -75.0 161.4 65.0 0.325 0.0
LYS D:487 C:487 65.0 0.325 -74.7 160.9 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 65.0 0.325 -83.5 146.1 65.0 0.325 0.0
LYS D:487 C:487 64.0 0.32 -84.8 146.3 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 65.0 0.325 -76.7 155.7 65.0 0.325 0.0
LYS D:487 C:487 68.0 0.34 -77.2 154.8 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 61.0 0.305 -74.4 171.0 61.0 0.305 0.0
LYS D:487 C:487 62.0 0.31 -74.0 170.4 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 LYS A:487 A:487 62.0 0.31 -77.1 156.0 62.0 0.31 0.0
LYS D:487 C:487 67.0 0.335 -77.3 155.5 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 LYS A:469 A:487 94.0 0.47 E -99.8 128.7 94.0 0.47 0.0
LYS D:469 C:487 93.0 0.465 E -99.1 128.2 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 LYS A:469 A:487 85.0 0.425 E -80.4 93.1 85.0 0.425 0.0
LYS D:469 C:487 87.0 0.435 E -79.8 94.6 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 LYS A:463 A:487 102.0 0.51 -76.9 109.3 102.0 0.51 0.0
LYS D:463 C:487 103.0 0.515 -77.5 108.9 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 GLU A:499 A:494 54.0 0.284 E -80.2 110.1 54.0 0.284 0.0
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 GLU A:499 A:494 63.0 0.332 E -65.1 126.8 63.0 0.332 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 54.0 0.284 E -80.1 110.1 54.0 0.284 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.1 110.0 53.0 0.279 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.2 110.1 53.0 0.279 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 54.0 0.284 E -80.1 110.0 54.0 0.284 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 54.0 0.284 E -80.1 110.0 54.0 0.284 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.1 110.0 53.0 0.279 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.2 110.0 53.0 0.279 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.2 110.1 53.0 0.279 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.2 110.0 53.0 0.279 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 54.0 0.284 E -80.1 110.0 54.0 0.284 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.1 110.1 53.0 0.279 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.2 110.0 53.0 0.279 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.2 110.0 53.0 0.279 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.2 110.0 53.0 0.279 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.2 110.1 53.0 0.279 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.3 110.1 53.0 0.279 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 54.0 0.284 E -80.1 110.1 54.0 0.284 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 53.0 0.279 E -80.3 110.2 53.0 0.279 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 54.0 0.284 E -80.2 110.2 54.0 0.284 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 GLU A:499 A:494 58.0 0.305 E -73.8 120.6 58.0 0.305 0.0
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 GLU A:110 A:487 36.0 0.189 E -83.2 111.2 36.0 0.189 0.0 HOH
 2.561
 OE2
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 GLU A:492 A:492 39.0 0.205 E -71.3 134.7
af-p13637-f1 1 P13637 88.37 0.0 GLU A:484 A:484 65.0 0.342 E -68.3 142.4
af-p05023-f1 1 P05023 86.71 0.0 LYS A:494 A:494 82.0 0.41 E -69.7 128.7
af-q13733-f1 1 Q13733 80.48 0.0 LEU A:502 A:502 22.0 0.129 E -82.1 134.4