Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160100303 . C A CCDS1196.1:NM_000702.3:c.1743tgC>tgA_NP_000693.1:p.581C>* Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 CYS A:582 A:582 1.0 0.007 E -113.3 109.4 1.0 0.007 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 CYS A:577 A:577 2.0 0.015 E -109.1 113.0 2.0 0.015 0.0 HOH
 8.071
 SG
 O
CYS D:577 C:577 2.0 0.015 E -112.5 112.1 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 CYS A:577 A:577 3.0 0.022 E -111.1 113.7 3.0 0.022 0.0 HOH
 8.026
 SG
 O
CYS D:577 C:577 3.0 0.022 E -106.1 120.0 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 CYS A:582 A:577 2.0 0.015 E -107.4 109.2 2.0 0.015 0.0
CYS D:582 C:577 3.0 0.022 E -107.8 109.7 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 CYS A:582 A:577 2.0 0.015 E -103.7 108.5 2.0 0.015 0.0
CYS D:582 C:577 3.0 0.022 E -103.5 108.4 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 CYS A:582 A:577 0.0 0.0 E -113.5 111.0 0.0 0.0 0.0
CYS D:582 C:577 0.0 0.0 E -113.4 110.7 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 CYS A:582 A:577 2.0 0.015 E -104.5 109.2 2.0 0.015 0.0
CYS D:582 C:577 2.0 0.015 E -104.4 109.1 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 CYS A:582 A:577 0.0 0.0 E -109.5 106.9 0.0 0.0 0.0
CYS D:582 C:577 0.0 0.0 E -109.3 105.0 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 2.0 0.015 E -104.5 115.3 2.0 0.015 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 2.0 0.015 E -105.6 112.7 2.0 0.015 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 0.0 0.0 E -114.6 106.7 0.0 0.0 0.0
CYS C:577 C:577 0.0 0.0 E -114.5 105.2 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 0.0 0.0 E -114.4 106.5 0.0 0.0 0.0
CYS D:577 C:577 1.0 0.007 E -113.9 105.5 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 0.0 0.0 E -117.6 102.6 0.0 0.0 0.0
CYS D:577 C:577 0.0 0.0 E -116.9 102.4 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 2.0 0.015 E -111.0 112.8 2.0 0.015 0.0
CYS D:577 C:577 1.0 0.007 E -110.5 112.6 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 0.0 0.0 E -107.1 104.6 0.0 0.0 0.0
CYS D:577 C:577 0.0 0.0 E -107.1 103.8 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 1.0 0.007 E -114.6 106.4 1.0 0.007 0.0
CYS D:577 C:577 0.0 0.0 E -114.2 105.5 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 0.0 0.0 E -110.5 108.1 0.0 0.0 0.0
CYS D:577 C:577 0.0 0.0 E -109.6 107.6 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 CYS A:577 A:577 1.0 0.007 E -114.8 105.5 1.0 0.007 0.0
CYS D:577 C:577 0.0 0.0 E -114.8 105.4 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 CYS A:559 A:577 2.0 0.015 E -108.3 116.9 2.0 0.015 0.0
CYS D:559 C:577 1.0 0.007 E -108.4 117.3 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 CYS A:559 A:577 0.0 0.0 E -81.4 148.2 0.0 0.0 0.0
CYS D:559 C:577 1.0 0.007 E -82.9 147.0 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 CYS A:553 A:577 0.0 0.0 E -93.6 106.4 0.0 0.0 0.0
CYS D:553 C:577 1.0 0.007 E -93.6 106.2 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0 HOH
 7.641
 O
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 CYS A:589 A:584 0.0 0.0 E -85.2 110.0 0.0 0.0 0.0
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.5 0.0 0.0 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.1 115.5 0.0 0.0 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.7 0.0 0.0 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.1 115.5 0.0 0.0 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.3 115.6 0.0 0.0 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.5 0.0 0.0 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.5 0.0 0.0 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.3 115.7 0.0 0.0 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.3 115.6 0.0 0.0 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.2 115.6 0.0 0.0 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.4 115.7 0.0 0.0 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -101.3 115.6 0.0 0.0 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 CYS A:589 A:584 0.0 0.0 E -104.6 111.2 0.0 0.0 0.0 HOH
 7.715
 O
 O
1q3i 1 ? 98.07 3e-145 X-RAY
 2004-08-03 CYS A:199 A:577 4.0 0.03 E -107.7 111.5 4.0 0.03 0.0 HOH
 4.745
 CB
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 CYS A:581 A:581 1.0 0.007 E -98.1 113.0
af-p13637-f1 1 P13637 88.37 0.0 CYS A:574 A:574 0.0 0.0 E -97.7 114.0
af-p05023-f1 1 P05023 86.71 0.0 CYS A:584 A:584 0.0 0.0 E -95.1 114.6
af-q13733-f1 1 Q13733 80.48 0.0 CYS A:590 A:590 2.0 0.015 E -97.1 115.4