Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105243 . C A CCDS1196.1:NM_000702.3:c.2135aCg>aAg_NP_000693.1:p.712T>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 THR A:713 A:713 2.0 0.014 E -127.5 130.8 2.0 0.014 0.0 MG
HOH
 6.982
7.122
 O
O
 MG
O
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:708 A:708 2.0 0.014 E -107.7 123.6 2.0 0.014 0.0 ALF
MG
HOH
 7.603
7.450
9.525
 O
O
O
 F4
MG
O
THR D:708 C:708 2.0 0.014 E -112.1 109.4 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:708 A:708 2.0 0.014 E -122.2 121.6 2.0 0.014 0.0 ALF
MG
ADP
HOH
 7.939
7.166
9.939
9.775
 O
O
O
N
 AL
MG
O3B
O
THR D:708 C:708 2.0 0.014 E -120.6 102.1 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 THR A:713 A:708 4.0 0.029 E -114.7 136.8 4.0 0.029 0.0 ALF
MG
 8.203
7.440
 O
O
 F3
MG
THR D:713 C:708 4.0 0.029 E -116.2 135.1 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 THR A:713 A:708 5.0 0.036 E -116.9 133.2 5.0 0.036 0.0 MG
 7.286
 O
 MG
THR D:713 C:708 5.0 0.036 E -116.3 133.5 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:713 A:708 1.0 0.007 E -111.4 129.3 1.0 0.007 0.0 MG
 7.686
 O
 MG
THR D:713 C:708 1.0 0.007 E -111.3 128.4 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:713 A:708 5.0 0.036 E -111.0 134.2 5.0 0.036 0.0 MG
 7.461
 O
 MG
THR D:713 C:708 4.0 0.029 E -111.0 134.0 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 THR A:713 A:708 1.0 0.007 E -113.3 108.3 1.0 0.007 0.0 MG
HOH
 7.259
7.501
 O
O
 MG
O
THR D:713 C:708 1.0 0.007 E -112.6 108.0 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 1.0 0.007 E -114.5 112.1 1.0 0.007 0.0 MG
HOH
 6.930
6.917
 O
O
 MG
O
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 1.0 0.007 E -114.9 112.1 1.0 0.007 0.0 MG
HOH
 6.787
6.913
 O
O
 MG
O
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 2.0 0.014 E -112.6 112.9 2.0 0.014 0.0 MG
HOH
 7.398
7.097
 O
O
 MG
O
THR C:708 C:708 2.0 0.014 E -112.1 114.0 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 1.0 0.007 E -112.8 112.6 1.0 0.007 0.0 MG
HOH
 7.213
6.939
 O
O
 MG
O
THR D:708 C:708 2.0 0.014 E -112.1 113.6 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 2.0 0.014 E -117.3 115.7 2.0 0.014 0.0 MG
HOH
 7.205
7.018
 O
O
 MG
O
THR D:708 C:708 3.0 0.021 E -115.9 116.5 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 0.0 0.0 E -108.9 121.8 0.0 0.0 0.0 MG
HOH
 6.998
7.209
 O
O
 MG
O
THR D:708 C:708 1.0 0.007 E -107.6 122.1 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 1.0 0.007 E -111.7 108.7 1.0 0.007 0.0 MG
HOH
 7.356
7.247
 O
O
 MG
O
THR D:708 C:708 1.0 0.007 E -112.3 109.8 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 2.0 0.014 E -112.6 111.7 2.0 0.014 0.0 MG
HOH
 7.285
7.167
 O
O
 MG
O
THR D:708 C:708 2.0 0.014 E -111.4 112.5 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 1.0 0.007 E -112.0 112.7 1.0 0.007 0.0 MG
HOH
 7.091
7.262
 O
O
 MG
O
THR D:708 C:708 1.0 0.007 E -110.9 112.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:708 A:708 2.0 0.014 E -113.5 114.0 2.0 0.014 0.0 MG
HOH
 7.286
6.774
 O
O
 MG
O
THR D:708 C:708 2.0 0.014 E -113.6 115.3 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 THR A:690 A:708 2.0 0.014 E -112.3 122.9 2.0 0.014 0.0 MG
MF4
 7.710
7.140
 O
O
 MG
F1
THR D:690 C:708 3.0 0.021 E -112.1 122.7 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 THR A:690 A:708 2.0 0.014 E -100.6 141.9 2.0 0.014 0.0 MF4
MG
 7.122
7.532
 O
O
 F1
MG
THR D:690 C:708 3.0 0.021 E -102.9 142.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:684 A:708 10.0 0.071 E -127.0 96.0 10.0 0.071 0.0 MG
 7.546
 O
 MG
THR D:684 C:708 10.0 0.071 E -127.6 95.6 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 THR A:720 A:715 4.0 0.029 E -117.4 130.6 4.0 0.029 0.0 MF4
MG
K
HOH
 7.643
7.018
9.923
6.837
 O
O
N
O
 F4
MG
K
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 THR A:720 A:715 2.0 0.014 E -116.1 127.5 2.0 0.014 0.0 MF4
MG
HOH
 7.732
7.322
7.105
 O
O
O
 F1
MG
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.643
7.018
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.3 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.644
7.019
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.5 4.0 0.029 0.0 MF4
MG
K
TL
 7.642
7.017
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.5 130.5 4.0 0.029 0.0 MF4
MG
K
TL
 7.642
7.017
9.924
9.924
 O
O
N
N
 F4
MG
K
TL
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.643
7.018
9.924
9.924
 O
O
N
N
 F4
MG
K
TL
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.643
7.017
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.5 130.5 4.0 0.029 0.0 MF4
MG
K
TL
 7.643
7.018
9.924
9.924
 O
O
N
N
 F4
MG
K
TL
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.643
7.019
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.642
7.018
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.3 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.643
7.017
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.3 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.642
7.018
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.7 4.0 0.029 0.0 MF4
MG
K
TL
 7.642
7.017
9.924
9.924
 O
O
N
N
 F4
MG
K
TL
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.3 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.643
7.018
9.923
9.923
 O
O
N
N
 F4
MG
K
TL
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.6 4.0 0.029 0.0 MF4
MG
K
TL
 7.642
7.019
9.924
9.924
 O
O
N
N
 F4
MG
K
TL
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.5 130.6 4.0 0.029 0.0 MF4
MG
K
RB
 7.643
7.017
9.923
9.923
 O
O
N
N
 F4
MG
K
RB
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.6 4.0 0.029 0.0 MF4
MG
K
RB
 7.643
7.018
9.924
9.924
 O
O
N
N
 F4
MG
K
RB
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.3 130.6 4.0 0.029 0.0 MF4
MG
K
RB
 7.644
7.019
9.924
9.924
 O
O
N
N
 F4
MG
K
RB
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.7 4.0 0.029 0.0 MF4
MG
K
RB
 7.643
7.017
9.924
9.924
 O
O
N
N
 F4
MG
K
RB
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 4.0 0.029 E -117.4 130.5 4.0 0.029 0.0 MF4
MG
RB
 7.642
7.018
9.923
 O
O
N
 F4
MG
RB
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:720 A:715 3.0 0.021 E -121.0 126.7 3.0 0.021 0.0 MF4
MG
K
HOH
 7.620
7.187
9.826
6.875
 O
O
N
O
 F4
MG
K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 THR A:712 A:712 1.0 0.007 E -114.2 127.6
af-p13637-f1 1 P13637 88.37 0.0 THR A:705 A:705 3.0 0.021 E -115.6 127.3
af-p05023-f1 1 P05023 86.71 0.0 THR A:715 A:715 3.0 0.021 E -118.2 129.3
af-q13733-f1 1 Q13733 80.48 0.0 THR A:721 A:721 2.0 0.014 E -114.2 129.3