Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105318 . A C CCDS1196.1:NM_000702.3:c.2210gAc>gCc_NP_000693.1:p.737D>A Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
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label_seq_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 ASP A:738 A:738 97.0 0.647 S -80.4 -42.1 97.0 0.647 0.0
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ASP A:733 A:733 38.0 0.253 H -55.3 -57.7 38.0 0.253 0.0
ASP D:733 C:733 31.0 0.207 H -66.7 -45.9 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 ASP A:733 A:733 33.0 0.22 H -49.2 -58.1 33.0 0.22 0.0
ASP D:733 C:733 33.0 0.22 H -65.5 -47.0 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 ASP A:738 A:733 24.0 0.16 H -71.1 -37.6 24.0 0.16 0.0
ASP D:738 C:733 23.0 0.153 H -70.3 -38.9 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 ASP A:738 A:733 84.0 0.56 H -79.0 -41.6 84.0 0.56 0.0
ASP D:738 C:733 80.0 0.533 H -79.0 -40.9 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ASP A:738 A:733 70.0 0.467 S -80.4 -40.7 70.0 0.467 0.0
ASP D:738 C:733 65.0 0.433 S -80.4 -41.4 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 ASP A:738 A:733 81.0 0.54 H -78.6 -43.0 81.0 0.54 0.0
ASP D:738 C:733 78.0 0.52 H -78.7 -42.4 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 ASP A:738 A:733 72.0 0.48 H -67.3 -33.0 72.0 0.48 0.0 HOH
 9.780
 N
 O
ASP D:738 C:733 68.0 0.453 H -66.5 -31.4 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 47.0 0.313 H -71.8 -37.2 47.0 0.313 0.0
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 49.0 0.327 H -67.7 -36.7 49.0 0.327 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 69.0 0.46 H -65.7 -36.5 69.0 0.46 0.0 HOH
 9.949
 N
 O
ASP C:733 C:733 69.0 0.46 H -65.6 -35.7 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 68.0 0.453 H -64.6 -36.8 68.0 0.453 0.0 HOH
 9.824
 N
 O
ASP D:733 C:733 71.0 0.473 H -64.2 -36.6 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 88.0 0.587 H -73.4 -30.6 88.0 0.587 0.0
ASP D:733 C:733 85.0 0.567 H -73.5 -32.2 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 74.0 0.493 H -84.4 -31.4 74.0 0.493 0.0
ASP D:733 C:733 72.0 0.48 H -84.4 -32.8 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 75.0 0.5 H -66.6 -35.7 75.0 0.5 0.0 HOH
 9.440
 N
 O
ASP D:733 C:733 70.0 0.467 H -66.4 -34.9 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 69.0 0.46 H -64.9 -36.6 69.0 0.46 0.0
ASP D:733 C:733 72.0 0.48 H -64.9 -37.2 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 76.0 0.507 H -65.0 -34.4 76.0 0.507 0.0 HOH
 9.914
 N
 O
ASP D:733 C:733 72.0 0.48 H -64.3 -33.0 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 ASP A:733 A:733 70.0 0.467 H -65.3 -35.6 70.0 0.467 0.0 HOH
 9.622
 N
 O
ASP D:733 C:733 71.0 0.473 H -63.8 -35.0 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 ASP A:715 A:733 124.0 0.827 T -62.0 26.1 124.0 0.827 0.0
ASP D:715 C:733 123.0 0.82 T -61.7 26.2 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 ASP A:715 A:733 107.0 0.713 H -29.3 -51.8 107.0 0.713 0.0
ASP D:715 C:733 111.0 0.74 H -27.8 -53.0 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 ASP A:709 A:733 96.0 0.64 H -58.3 -64.9 96.0 0.64 0.0
ASP D:709 C:733 66.0 0.44 H -58.2 -65.0 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 ASP A:745 A:740 81.0 0.54 H -52.1 -46.5 81.0 0.54 0.0 HOH
 3.516
 N
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 ASP A:745 A:740 75.0 0.5 H -68.6 -31.0 75.0 0.5 0.0 HOH
 9.871
 O
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.2 -46.5 82.0 0.547 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.0 -46.6 82.0 0.547 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.0 -46.5 82.0 0.547 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.6 82.0 0.547 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.0 -46.5 82.0 0.547 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.0 -46.6 82.0 0.547 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.6 82.0 0.547 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.6 82.0 0.547 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 81.0 0.54 H -52.2 -46.4 81.0 0.54 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.2 -46.4 82.0 0.547 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 82.0 0.547 H -52.1 -46.5 82.0 0.547 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 ASP A:745 A:740 80.0 0.533 H -56.7 -41.0 80.0 0.533 0.0 HOH
 3.535
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 ASP A:737 A:737 103.0 0.687 H -60.9 -31.1
af-p13637-f1 1 P13637 88.37 0.0 ASP A:730 A:730 46.0 0.307 H -66.7 -34.2
af-p05023-f1 1 P05023 86.71 0.0 ASP A:740 A:740 57.0 0.38 H -65.2 -30.1
af-q13733-f1 1 Q13733 80.48 0.0 ASP A:746 A:746 94.0 0.627 H -60.8 -25.1