Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105776 . C A CCDS1196.1:NM_000702.3:c.2432aCa>aAa_NP_000693.1:p.811T>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 THR A:812 A:812 0.0 0.0 T -119.4 -58.8 0.0 0.0 0.0 MG
HOH
 9.999
9.302
 OG1
OG1
 MG
O
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:807 A:807 1.0 0.007 H -108.5 -32.8 1.0 0.007 0.0 NA
NA
NA
PC1
HOH
 8.829
6.989
5.040
7.495
6.762
 C
OG1
OG1
N
C
 NA
NA
NA
C3F
O
THR D:807 C:807 2.0 0.014 H -131.6 -6.0 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 THR A:807 A:807 1.0 0.007 H -109.7 -27.8 1.0 0.007 0.0 NA
NA
NA
PC1
HOH
 8.637
6.962
5.021
7.533
6.701
 C
OG1
O
N
C
 NA
NA
NA
C3F
O
THR D:807 C:807 1.0 0.007 H -125.4 -11.7 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 THR A:812 A:807 0.0 0.0 T -102.8 -10.8 0.0 0.0 0.0 NA
NA
NA
 8.421
6.561
6.157
 CG2
CG2
CG2
 NA
NA
NA
THR D:812 C:807 0.0 0.0 T -104.4 -9.8 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 THR A:812 A:807 0.0 0.0 I -94.4 -60.4 0.0 0.0 0.0 HOH
 9.952
 OG1
 O
THR D:812 C:807 0.0 0.0 I -93.8 -60.0 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:812 A:807 0.0 0.0 I -101.5 -58.9 0.0 0.0 0.0 K
 9.848
 OG1
 K
THR D:812 C:807 0.0 0.0 I -101.3 -59.5 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 THR A:812 A:807 0.0 0.0 I -105.9 -60.1 0.0 0.0 0.0 HOH
 9.780
 OG1
 O
THR D:812 C:807 0.0 0.0 I -106.9 -60.0 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 THR A:812 A:807 0.0 0.0 I -65.3 -49.3 0.0 0.0 0.0 PCW
 9.998
 O
 O31
THR D:812 C:807 0.0 0.0 I -66.0 -46.8 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -56.7 -59.7 0.0 0.0 0.0 PCW
PCW
 9.053
9.427
 O
O
 O31
C32
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -57.1 -57.2 0.0 0.0 0.0
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -66.3 -61.0 0.0 0.0 0.0 PCW
 7.848
 O
 C32
THR C:807 C:807 0.0 0.0 I -66.6 -60.7 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -64.8 -61.1 0.0 0.0 0.0 RB
PCW
HOH
 9.506
9.272
7.515
 OG1
O
C
 RB
C32
O
THR D:807 C:807 0.0 0.0 I -64.6 -60.1 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -64.8 -55.9 0.0 0.0 0.0 PCW
 8.284
 O
 C32
THR D:807 C:807 0.0 0.0 I -64.2 -58.6 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -64.0 -55.3 0.0 0.0 0.0
THR D:807 C:807 0.0 0.0 I -65.9 -56.9 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -66.0 -59.4 0.0 0.0 0.0 PCW
 8.718
 O
 O31
THR D:807 C:807 0.0 0.0 I -65.1 -58.8 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -66.1 -61.1 0.0 0.0 0.0 PCW
 9.482
 O
 O31
THR D:807 C:807 0.0 0.0 I -65.8 -61.0 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -61.8 -63.5 0.0 0.0 0.0 PCW
 8.255
 O
 C32
THR D:807 C:807 0.0 0.0 I -62.0 -64.9 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 THR A:807 A:807 0.0 0.0 I -63.2 -63.0 0.0 0.0 0.0 PCW
 7.128
 O
 O31
THR D:807 C:807 0.0 0.0 I -62.0 -62.2 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 THR A:789 A:807 1.0 0.007 T -100.3 -70.9 1.0 0.007 0.0 RB
 8.949
 CB
 RB
THR D:789 C:807 4.0 0.029 I -89.4 -63.8 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 THR A:789 A:807 0.0 0.0 I -57.7 -43.7 0.0 0.0 0.0 RB
 8.438
 OG1
 RB
THR D:789 C:807 0.0 0.0 I -54.0 -44.8 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 THR A:783 A:807 0.0 0.0 I -100.6 -26.4 0.0 0.0 0.0
THR D:783 C:807 0.0 0.0 I -101.3 -26.4 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 THR A:819 A:814 2.0 0.014 I -67.6 -42.5 2.0 0.014 0.0 K
HOH
 8.660
2.582
 OG1
OG1
 K
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 THR A:819 A:814 1.0 0.007 I -73.5 -30.1 1.0 0.007 0.0 K
HOH
 8.974
2.528
 OG1
OG1
 K
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.6 2.0 0.014 0.0 K
TL
HOH
 8.661
8.661
6.719
 OG1
OG1
C
 K
TL
O
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.5 2.0 0.014 0.0 K
TL
HOH
 8.660
8.660
6.718
 OG1
OG1
C
 K
TL
O
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.7 -42.5 2.0 0.014 0.0 K
TL
HOH
 8.661
8.661
6.718
 OG1
OG1
C
 K
TL
O
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.5 -42.6 2.0 0.014 0.0 K
TL
HOH
 8.660
8.660
6.718
 OG1
OG1
C
 K
TL
O
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.5 2.0 0.014 0.0 K
TL
HOH
 8.661
8.661
6.719
 OG1
OG1
C
 K
TL
O
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.5 2.0 0.014 0.0 TL
HOH
 8.660
6.718
 OG1
C
 TL
O
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.5 -42.6 2.0 0.014 0.0 TL
HOH
 8.659
6.718
 OG1
C
 TL
O
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.5 2.0 0.014 0.0 TL
HOH
 8.661
6.719
 OG1
C
 TL
O
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.7 -42.4 2.0 0.014 0.0 TL
HOH
 8.661
6.718
 OG1
C
 TL
O
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.4 2.0 0.014 0.0 TL
HOH
 8.660
6.718
 OG1
C
 TL
O
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.5 2.0 0.014 0.0 TL
HOH
 8.661
6.717
 OG1
C
 TL
O
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.7 -42.5 2.0 0.014 0.0 K
TL
HOH
 8.660
8.660
6.717
 OG1
OG1
C
 K
TL
O
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.5 -42.6 2.0 0.014 0.0 TL
HOH
 8.660
6.718
 OG1
C
 TL
O
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.5 -42.5 2.0 0.014 0.0 TL
HOH
 8.660
6.718
 OG1
C
 TL
O
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.5 -42.5 2.0 0.014 0.0 K
RB
HOH
 8.660
8.660
6.719
 OG1
OG1
C
 K
RB
O
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.5 -42.5 2.0 0.014 0.0 K
RB
HOH
 8.660
8.660
6.718
 OG1
OG1
C
 K
RB
O
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.5 2.0 0.014 0.0 K
RB
HOH
 8.660
8.660
6.719
 OG1
OG1
C
 K
RB
O
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.5 -42.5 2.0 0.014 0.0 K
RB
HOH
 8.660
8.660
6.719
 OG1
OG1
C
 K
RB
O
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -67.6 -42.6 2.0 0.014 0.0 RB
HOH
 8.660
6.718
 OG1
C
 RB
O
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 THR A:819 A:814 2.0 0.014 I -69.1 -36.4 2.0 0.014 0.0 K
HOH
 8.683
2.456
 OG1
OG1
 K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 THR A:811 A:811 0.0 0.0 I -60.7 -40.4
af-p13637-f1 1 P13637 88.37 0.0 THR A:804 A:804 0.0 0.0 I -61.1 -40.7
af-p05023-f1 1 P05023 86.71 0.0 THR A:814 A:814 0.0 0.0 I -62.5 -40.5
af-q13733-f1 1 Q13733 80.48 0.0 THR A:820 A:820 0.0 0.0 I -62.9 -40.3