Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160105782 . T A CCDS1196.1:NM_000702.3:c.2438aTg>aAg_NP_000693.1:p.813M>K Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 MET A:814 A:814 39.0 0.211 H -53.9 -59.0 39.0 0.211 0.0 HOH
 9.077
 SD
 O
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 MET A:809 A:809 19.0 0.103 S -127.0 -87.3 19.0 0.103 0.0 NA
NA
NA
PC1
HOH
 7.227
8.311
7.441
3.994
5.924
 CE
N
N
CG
N
 NA
NA
NA
C39
O
MET D:809 C:809 20.0 0.108 S -107.9 -80.7 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 MET A:809 A:809 18.0 0.097 S -120.9 -95.6 18.0 0.097 0.0 NA
NA
NA
PC1
HOH
 6.861
8.222
7.403
4.112
6.012
 CE
N
N
CG
N
 NA
NA
NA
C39
O
MET D:809 C:809 22.0 0.119 S -107.1 -94.4 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 MET A:814 A:809 32.0 0.173 H -67.1 -70.5 32.0 0.173 0.0 NA
NA
 7.595
9.084
 N
N
 NA
NA
MET D:814 C:809 32.0 0.173 H -67.1 -70.6 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 MET A:814 A:809 39.0 0.211 H -55.4 -58.3 39.0 0.211 0.0 HOH
 9.666
 SD
 O
MET D:814 C:809 39.0 0.211 H -55.8 -58.6 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 MET A:814 A:809 47.0 0.254 H -53.9 -57.1 47.0 0.254 0.0 K
 9.428
 N
 K
MET D:814 C:809 47.0 0.254 H -54.3 -56.5 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 MET A:814 A:809 38.0 0.205 H -54.7 -58.2 38.0 0.205 0.0 HOH
 9.271
 SD
 O
MET D:814 C:809 39.0 0.211 H -54.6 -58.2 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 MET A:814 A:809 48.0 0.259 H -64.0 -41.8 48.0 0.259 0.0 MG
PCW
PCW
HOH
 9.526
9.807
7.202
9.164
 SD
CE
CB
SD
 MG
O11
O31
O
MET D:814 C:809 47.0 0.254 H -64.3 -41.1 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 45.0 0.243 H -71.4 -53.5 45.0 0.243 0.0 PCW
PCW
PCW
 9.818
6.053
4.885
 CE
O
CE
 C12
O31
C32
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 45.0 0.243 H -69.0 -52.2 45.0 0.243 0.0 PCW
PCW
 9.325
8.164
 CE
C
 C12
O31
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 45.0 0.243 H -62.5 -45.2 45.0 0.243 0.0 MG
PCW
PCW
HOH
 9.892
8.715
5.428
9.605
 SD
CE
O
SD
 MG
C32
C32
O
MET C:809 C:809 43.0 0.232 H -61.6 -44.7 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 45.0 0.243 H -61.4 -46.0 45.0 0.243 0.0 RB
PCW
PCW
HOH
 9.441
9.090
6.329
4.680
 N
CE
O
SD
 RB
C12
C32
O
MET D:809 C:809 45.0 0.243 H -61.3 -45.7 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 47.0 0.254 H -67.2 -48.9 47.0 0.254 0.0 PCW
PCW
HOH
 9.007
5.173
9.657
 CE
O
SD
 C12
C32
O
MET D:809 C:809 45.0 0.243 H -68.2 -48.8 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 45.0 0.243 H -73.0 -53.3 45.0 0.243 0.0 PCW
PCW
 9.640
7.666
 CE
C
 O11
O31
MET D:809 C:809 47.0 0.254 H -72.7 -52.1 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 47.0 0.254 H -63.0 -48.8 47.0 0.254 0.0 MG
PCW
PCW
HOH
 9.616
9.335
5.189
9.033
 SD
CE
O
SD
 MG
C12
O31
O
MET D:809 C:809 47.0 0.254 H -63.2 -48.1 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 42.0 0.227 H -62.9 -44.7 42.0 0.227 0.0 MG
PCW
PCW
HOH
 9.937
9.268
7.859
9.666
 SD
CE
O
SD
 MG
C12
O31
O
MET D:809 C:809 43.0 0.232 H -62.0 -45.0 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 42.0 0.227 H -64.5 -49.4 42.0 0.227 0.0 MG
PCW
HOH
 9.844
5.692
9.496
 SD
O
SD
 MG
O31
O
MET D:809 C:809 43.0 0.232 H -63.8 -48.4 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 MET A:809 A:809 45.0 0.243 H -62.0 -45.0 45.0 0.243 0.0 MG
PCW
PCW
HOH
 9.804
9.278
4.307
9.388
 SD
CE
O
SD
 MG
C12
O31
O
MET D:809 C:809 49.0 0.265 H -61.3 -46.0 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 MET A:791 A:809 72.0 0.389 H -43.2 -88.1 72.0 0.389 0.0 RB
 8.977
 N
 RB
MET D:791 C:809 45.0 0.243 H -42.2 -82.3 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 MET A:791 A:809 57.0 0.308 H -38.0 -80.9 57.0 0.308 0.0 RB
 8.466
 N
 RB
MET D:791 C:809 53.0 0.286 H -41.8 -78.2 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 MET A:785 A:809 56.0 0.303 S -112.6 -40.9 56.0 0.303 0.0
MET D:785 C:809 56.0 0.303 S -114.2 -40.6 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 MET A:821 A:816 45.0 0.243 H -60.2 -61.1 45.0 0.243 0.0 K
HOH
 8.762
3.708
 N
N
 K
O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 MET A:821 A:816 42.0 0.227 H -65.0 -64.5 42.0 0.227 0.0 K
HOH
 8.879
5.945
 N
N
 K
O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.1 45.0 0.243 0.0 K
TL
HOH
 8.763
8.763
6.028
 N
N
N
 K
TL
O
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.1 45.0 0.243 0.0 K
TL
HOH
 8.762
8.762
6.026
 N
N
N
 K
TL
O
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.1 45.0 0.243 0.0 K
TL
HOH
 8.762
8.762
6.027
 N
N
N
 K
TL
O
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.1 45.0 0.243 0.0 K
TL
HOH
 8.761
8.761
6.025
 N
N
N
 K
TL
O
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.2 45.0 0.243 0.0 K
TL
HOH
 8.761
8.761
6.025
 N
N
N
 K
TL
O
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.0 45.0 0.243 0.0 TL
HOH
 8.761
6.026
 N
N
 TL
O
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.1 -61.1 45.0 0.243 0.0 TL
HOH
 8.761
6.025
 N
N
 TL
O
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.1 -61.2 45.0 0.243 0.0 TL
HOH
 8.763
6.027
 N
N
 TL
O
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.2 45.0 0.243 0.0 TL
HOH
 8.762
6.026
 N
N
 TL
O
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.0 45.0 0.243 0.0 TL
HOH
 8.762
6.026
 N
N
 TL
O
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.1 -61.2 45.0 0.243 0.0 TL
HOH
 8.762
6.025
 N
N
 TL
O
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.1 45.0 0.243 0.0 K
TL
HOH
 8.762
8.762
6.026
 N
N
N
 K
TL
O
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.1 -61.1 45.0 0.243 0.0 TL
HOH
 8.761
6.026
 N
N
 TL
O
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.2 45.0 0.243 0.0 TL
HOH
 8.761
6.025
 N
N
 TL
O
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.3 -61.1 45.0 0.243 0.0 K
RB
HOH
 8.762
8.762
6.026
 N
N
N
 K
RB
O
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.1 45.0 0.243 0.0 K
RB
HOH
 8.762
8.762
6.025
 N
N
N
 K
RB
O
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.0 45.0 0.243 0.0 K
RB
HOH
 8.762
8.762
6.027
 N
N
N
 K
RB
O
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.0 45.0 0.243 0.0 K
RB
HOH
 8.762
8.762
6.024
 N
N
N
 K
RB
O
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 45.0 0.243 H -60.2 -61.1 45.0 0.243 0.0 RB
HOH
 8.761
6.025
 N
N
 RB
O
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 MET A:821 A:816 44.0 0.238 H -54.2 -67.5 44.0 0.238 0.0 K
HOH
 8.675
3.768
 N
N
 K
O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 MET A:813 A:813 39.0 0.211 H -62.0 -52.7
af-p13637-f1 1 P13637 88.37 0.0 MET A:806 A:806 38.0 0.205 H -62.4 -53.4
af-p05023-f1 1 P05023 86.71 0.0 MET A:816 A:816 38.0 0.205 H -62.1 -52.3
af-q13733-f1 1 Q13733 80.48 0.0 MET A:822 A:822 38.0 0.205 H -63.0 -52.9