Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 160106754 . G A CCDS1196.1:NM_000702.3:c.2773Gtg>Atg_NP_000693.1:p.925V>M Homo sapiens ATPase Na+/K+ transporting subunit alpha 2 (ATP1A2), mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
4xe5 1 Q08DA1 86.79 0.0 X-RAY
 2016-03-09 VAL A:926 A:926 2.0 0.013 H -58.4 -47.7 2.0 0.013 0.0 CLR
 6.675
 CG2
 C18
3wgu 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 VAL A:921 A:921 1.0 0.006 H -63.5 -50.7 1.0 0.006 0.0 NA
CLR
 9.924
5.852
 C
CG2
 NA
C21
VAL D:921 C:921 1.0 0.006 H -74.8 -28.0 NA NA NA
3wgv 1 I7HD36 87.32 0.0 X-RAY
 2013-10-09 VAL A:921 A:921 1.0 0.006 H -55.8 -54.1 1.0 0.006 0.0 NA
CLR
 9.870
7.294
 C
CG2
 NA
C21
VAL D:921 C:921 1.0 0.006 H -69.0 -28.3 NA NA NA
4hqj 1 P05024 86.69 0.0 X-RAY
 2013-10-02 VAL A:926 A:921 0.0 0.0 H -66.2 -38.3 0.0 0.0 0.0 NA
CLR
 9.291
5.516
 C
CG2
 NA
C12
VAL D:926 C:921 0.0 0.0 H -64.7 -37.3 NA NA NA
4hyt 1 P05024 86.69 0.0 X-RAY
 2013-06-26 VAL A:926 A:921 0.0 0.0 H -54.9 -44.7 0.0 0.0 0.0 CLR
 6.837
 CG1
 C24
VAL D:926 C:921 0.0 0.0 H -56.6 -44.0 NA NA NA
4res 1 P05024 86.69 0.0 X-RAY
 2015-01-28 VAL A:926 A:921 0.0 0.0 H -55.0 -37.4 0.0 0.0 0.0 CLR
 6.673
 CG2
 C18
VAL D:926 C:921 0.0 0.0 H -55.2 -37.6 NA NA NA
4ret 1 P05024 86.69 0.0 X-RAY
 2015-01-28 VAL A:926 A:921 1.0 0.006 H -60.7 -44.1 1.0 0.006 0.0 CLR
 6.720
 CG1
 C23
VAL D:926 C:921 0.0 0.0 H -61.3 -43.9 NA NA NA
7evx 1 P05024 86.69 0.0 X-RAY
 2021-07-07 VAL A:926 A:921 1.0 0.006 H -62.3 -45.5 1.0 0.006 0.0 CLR
 6.249
 CG2
 C18
VAL D:926 C:921 1.0 0.006 H -62.2 -44.1 NA NA NA
7d91 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 1.0 0.006 H -60.5 -46.6 1.0 0.006 0.0 CLR
 6.902
 CG2
 C18
7d92 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 2.0 0.013 H -59.4 -47.7 2.0 0.013 0.0 CLR
 7.191
 CG2
 C18
7d93 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 1.0 0.006 H -63.7 -42.7 1.0 0.006 0.0 CLR
 6.468
 CG2
 C18
VAL C:921 C:921 0.0 0.0 H -64.0 -42.5 NA NA NA
7d94 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 1.0 0.006 H -63.4 -43.4 1.0 0.006 0.0 CLR
 6.317
 CG2
 C18
VAL D:921 C:921 0.0 0.0 H -63.2 -43.4 NA NA NA
7ddf 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 2.0 0.013 H -62.8 -44.3 2.0 0.013 0.0 CLR
 6.091
 CG2
 C18
VAL D:921 C:921 3.0 0.019 H -63.1 -44.8 NA NA NA
7ddh 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 2.0 0.013 H -61.8 -44.9 2.0 0.013 0.0 CLR
 6.116
 CG2
 C18
VAL D:921 C:921 2.0 0.013 H -60.7 -44.7 NA NA NA
7ddi 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 2.0 0.013 H -62.4 -44.3 2.0 0.013 0.0 CLR
 6.246
 CG2
 C18
VAL D:921 C:921 1.0 0.006 H -61.9 -43.4 NA NA NA
7ddj 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 0.0 0.0 H -62.7 -43.5 0.0 0.0 0.0 CLR
 6.421
 CG2
 C15
VAL D:921 C:921 1.0 0.006 H -63.7 -43.5 NA NA NA
7ddk 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 2.0 0.013 H -63.3 -42.0 2.0 0.013 0.0 CLR
 6.270
 CG2
 C18
VAL D:921 C:921 1.0 0.006 H -62.4 -41.3 NA NA NA
7ddl 1 P05024 86.82 0.0 X-RAY
 2021-01-27 VAL A:921 A:921 1.0 0.006 H -62.2 -43.9 1.0 0.006 0.0 CLR
 6.314
 CG2
 C18
VAL D:921 C:921 1.0 0.006 H -62.8 -43.9 NA NA NA
3b8e 1 P05024 87.56 0.0 X-RAY
 2007-12-18 VAL A:903 A:921 3.0 0.019 H -48.7 -32.9 3.0 0.019 0.0
VAL D:903 C:921 5.0 0.032 H -42.3 -54.2 NA NA NA
3kdp 1 P05024 87.56 0.0 X-RAY
 2010-02-16 VAL A:903 A:921 0.0 0.0 H -74.8 -37.3 0.0 0.0 0.0
VAL D:903 C:921 1.0 0.006 H -76.1 -36.7 NA NA NA
3n23 1 P05024 87.8 0.0 X-RAY
 2011-01-19 VAL A:897 A:921 8.0 0.052 H -67.3 -23.6 8.0 0.052 0.0
VAL D:897 C:921 8.0 0.052 H -68.6 -23.1 NA NA NA
2zxe 1 Q4H132 84.65 0.0 X-RAY
 2009-05-19 VAL A:933 A:928 0.0 0.0 H -62.5 -41.0 0.0 0.0 0.0 HOH
 6.203
 N
 O
3a3y 1 Q4H132 84.65 0.0 X-RAY
 2009-09-08 VAL A:933 A:928 1.0 0.006 H -54.8 -40.9 1.0 0.006 0.0 HOH
 6.584
 N
 O
5avq 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.6 -41.0 0.0 0.0 0.0
5avr 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.4 -41.0 0.0 0.0 0.0
5avs 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.1 0.0 0.0 0.0
5avt 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.6 -41.0 0.0 0.0 0.0
5avu 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.1 0.0 0.0 0.0
5avv 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.4 -41.1 0.0 0.0 0.0
5avw 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.6 -40.9 0.0 0.0 0.0
5avx 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.1 0.0 0.0 0.0
5avy 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.0 0.0 0.0 0.0
5avz 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.1 0.0 0.0 0.0
5aw0 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.1 0.0 0.0 0.0
5aw1 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.1 0.0 0.0 0.0
5aw2 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.1 0.0 0.0 0.0
5aw3 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.4 -41.2 0.0 0.0 0.0
5aw4 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.0 0.0 0.0 0.0
5aw5 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.0 0.0 0.0 0.0
5aw6 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.0 0.0 0.0 0.0
5aw7 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.1 0.0 0.0 0.0
5aw8 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -62.5 -41.0 0.0 0.0 0.0
5aw9 1 Q4H132 84.65 0.0 X-RAY
 2015-09-02 VAL A:933 A:928 0.0 0.0 H -63.9 -40.6 0.0 0.0 0.0 HOH
 6.297
 N
 O

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p50993-f1 1 P50993 100.0 0.0 VAL A:925 A:925 1.0 0.006 H -63.7 -38.0
af-p13637-f1 1 P13637 88.37 0.0 VAL A:918 A:918 1.0 0.006 H -64.0 -38.1
af-p05023-f1 1 P05023 86.71 0.0 VAL A:928 A:928 0.0 0.0 H -63.5 -38.7
af-q13733-f1 1 Q13733 80.48 0.0 VAL A:934 A:934 2.0 0.013 H -66.5 -35.4