Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196658559 . G A CCDS1385.1:NM_000186.3:c.974tGt>tAt_NP_000177.2:p.325C>Y Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
5o32 3 P08603 82.35 1e-175 X-RAY
 2017-06-28 CYS C:320 C:1167 16.0 0.119 -118.3 159.4 16.0 0.119 0.0
CYS H:320 G:1167 8.0 0.059 E -114.8 133.3 8.0 0.059 0.0
5o35 3 P08603 82.61 5e-175 X-RAY
 2017-06-28 CYS C:319 C:1167 8.0 0.059 E -103.4 136.5 7.0 0.052 0.007 B:P01024:0.007
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 CYS A:6 A:325 11.0 0.081 B -102.4 146.7 11.0 0.081 0.0 HOH
 5.016
 O
 O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 CYS A:6 A:325 16.0 0.119 B -84.9 146.5 16.0 0.119 0.0 HOH
 8.826
 CB
 O
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 CYS A:7 A:325 9.0 0.067 B -84.5 129.4 9.0 0.067 0.0 HOH
 3.678
 CA
 O
CYS B:7 B:325 9.0 0.067 B -105.5 126.8 NA NA NA
CYS E:7 E:325 8.0 0.059 B -89.6 131.1 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 CYS A:7 A:325 8.0 0.059 B -99.7 129.8 8.0 0.059 0.0 EDO
EDO
HOH
 8.210
8.879
7.309
 SG
N
C
 O2
C2
O
CYS B:7 B:325 9.0 0.067 B -100.5 130.5 NA NA NA
CYS E:7 E:325 10.0 0.074 B -100.0 130.3 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 CYS A:7 A:325 11.0 0.081 B -88.5 130.9 11.0 0.081 0.0 HOH
 3.539
 CA
 O
CYS C:7 E:325 39.0 0.289 360.0 131.3 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 CYS A:7 A:325 40.0 0.296 360.0 136.1 NA NA NA
CYS B:7 B:325 40.0 0.296 360.0 135.1 40.0 0.296 0.0
CYS E:7 E:325 39.0 0.289 360.0 135.4 NA NA NA
CYS F:7 F:325 40.0 0.296 360.0 135.5 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 CYS A:5 A:325 5.0 0.037 B -92.6 128.6 5.0 0.037 0.0 HOH
 4.996
 N
 O
CYS B:5 B:325 4.0 0.03 B -89.7 124.9 NA NA NA
CYS E:5 E:325 4.0 0.03 B -103.2 126.5 NA NA NA
CYS G:5 G:325 4.0 0.03 B -95.8 125.0 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 CYS A:5 A:325 39.0 0.289 360.0 126.5 39.0 0.289 0.0 HOH
 3.686
 SG
 O
CYS B:5 B:325 3.0 0.022 B -90.0 108.3 NA NA NA
CYS E:5 E:325 4.0 0.03 B -91.4 113.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 CYS A:325 A:325 5.0 0.037 B -83.5 122.0