Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196658641 . T A CCDS1385.1:NM_000186.3:c.1056taT>taA_NP_000177.2:p.352Y>* Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 TYR A:33 A:352 134.0 0.583 E -141.0 145.9 134.0 0.583 0.0 HOH
 3.562
 CD2
 O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 TYR A:33 A:352 129.0 0.561 E -131.7 153.9 129.0 0.561 0.0 HOH
 7.176
 N
 O
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 TYR A:34 A:352 139.0 0.604 E -140.0 150.7 3.0 0.013 0.591 D:Q9JXV4:0.591
 EDO
HOH
 4.607
2.699
 O
O
 O1
O
TYR B:34 B:352 138.0 0.6 E -140.1 150.9 NA NA NA
TYR E:34 E:352 136.0 0.591 E -140.3 150.8 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 TYR A:34 A:352 138.0 0.6 E -137.7 148.9 7.0 0.03 0.57 D:Q9JXV4:0.57
 EDO
EDO
EDO
HOH
 3.304
4.765
4.943
6.856
 CD1
CD1
O
O
 O2
O1
C1
O
TYR B:34 B:352 140.0 0.609 E -137.5 149.7 NA NA NA
TYR E:34 E:352 136.0 0.591 E -137.6 149.4 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 TYR A:34 A:352 139.0 0.604 E -146.9 151.0 2.0 0.009 0.595 B:Q19KF7:0.596
 EDO
HOH
 4.835
2.798
 O
O
 O2
O
TYR C:34 E:352 137.0 0.596 E -146.5 150.5 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 TYR A:34 A:352 136.0 0.591 E -149.5 153.5 NA NA NA
TYR B:34 B:352 134.0 0.583 E -149.7 153.6 3.0 0.013 0.57 C:Q19KF7:0.57
 HOH
 5.027
 O
 O
TYR E:34 E:352 132.0 0.574 E -149.5 154.1 NA NA NA
TYR F:34 F:352 131.0 0.57 E -149.2 152.7 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 TYR A:32 A:352 138.0 0.6 E -152.3 156.2 4.0 0.017 0.583 D:Q9JXV4:0.583
 HOH
 2.833
 O
 O
TYR B:32 B:352 135.0 0.587 E -150.5 153.7 NA NA NA
TYR E:32 E:352 137.0 0.596 E -146.1 152.9 NA NA NA
TYR G:32 G:352 134.0 0.583 E -147.3 155.4 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 TYR A:32 A:352 133.0 0.578 E -164.5 146.4 6.0 0.026 0.552 D:Q9JXV4:0.552
 HOH
 3.417
 CE2
 O
TYR B:32 B:352 132.0 0.574 E -156.3 145.4 NA NA NA
TYR E:32 E:352 134.0 0.583 E -155.2 151.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 TYR A:352 A:352 142.0 0.617 E -142.2 153.9