Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196658660 . G A CCDS1385.1:NM_000186.3:c.1075Gaa>Aaa_NP_000177.2:p.359E>K Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 GLU A:40 A:359 153.0 0.805 T -55.0 144.5 153.0 0.805 0.0 GU4
YYJ
HOH
 9.722
4.431
3.021
 OE2
OE2
CA
 O27
O2S6
O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 GLU A:40 A:359 153.0 0.805 T -54.7 141.1 153.0 0.805 0.0 GU4
YYJ
HOH
 9.622
5.498
3.332
 OE2
OE2
OE1
 O11
O3S1
O
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLU A:41 A:359 155.0 0.816 T -56.1 137.8 99.0 0.521 0.295 D:Q9JXV4:0.295
 HOH
 2.804
 O
 O
GLU B:41 B:359 152.0 0.8 T -56.6 139.6 NA NA NA
GLU E:41 E:359 153.0 0.805 T -56.3 140.0 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLU A:41 A:359 156.0 0.821 T -50.5 130.5 46.0 0.242 0.579 D:Q9JXV4:0.579
 HOH
 4.396
 OE2
 O
GLU B:41 B:359 154.0 0.811 T -55.0 136.8 NA NA NA
GLU E:41 E:359 152.0 0.8 T -30.3 -65.5 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLU A:41 A:359 155.0 0.816 T -52.1 137.9 79.0 0.416 0.4 B:Q19KF7:0.4
 HOH
 2.963
 N
 O
GLU C:41 E:359 164.0 0.863 T -48.7 136.6 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLU A:41 A:359 157.0 0.826 T -53.1 136.2 NA NA NA
GLU B:41 B:359 157.0 0.826 T -52.8 136.2 82.0 0.432 0.394 C:Q19KF7:0.395
GLU E:41 E:359 158.0 0.832 T -54.0 137.7 NA NA NA
GLU F:41 F:359 159.0 0.837 T -54.9 139.8 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 GLU A:39 A:359 145.0 0.763 T -57.7 125.3 29.0 0.153 0.61 D:Q9JXV4:0.611
 HOH
 2.410
 O
 O
GLU B:39 B:359 152.0 0.8 T -65.5 144.5 NA NA NA
GLU E:39 E:359 153.0 0.805 T -52.7 132.8 NA NA NA
GLU G:39 G:359 153.0 0.805 T -59.1 136.2 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 GLU A:39 A:359 146.0 0.768 T -49.9 137.8 43.0 0.226 0.542 D:Q9JXV4:0.542
 HOH
 3.004
 CG
 O
GLU B:39 B:359 153.0 0.805 T -67.5 135.4 NA NA NA
GLU E:39 E:359 147.0 0.774 T -49.1 -33.9 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLU A:359 A:359 163.0 0.858 T -58.3 140.1