Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196658682 . G A CCDS1385.1:NM_000186.3:c.1097gGa>gAa_NP_000177.2:p.366G>E Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 GLY A:47 A:366 36.0 0.48 S 102.9 7.9 36.0 0.48 0.0 SO4
SO4
SO4
HOH
 9.921
6.890
6.284
3.710
 O
CA
O
O
 O4
O1
O1
O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 GLY A:47 A:366 35.0 0.467 S 90.5 13.3 35.0 0.467 0.0 SO4
SO4
HOH
 7.110
6.493
7.468
 CA
O
CA
 O1
O1
O
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLY A:48 A:366 39.0 0.52 S 90.9 29.6 15.0 0.2 0.32 D:Q9JXV4:0.32
 HOH
 3.388
 O
 O
GLY B:48 B:366 39.0 0.52 S 90.8 28.8 NA NA NA
GLY E:48 E:366 39.0 0.52 S 92.1 27.4 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLY A:48 A:366 31.0 0.413 S 91.2 5.8 24.0 0.32 0.093 D:Q9JXV4:0.093
 HOH
 7.292
 C
 O
GLY B:48 B:366 34.0 0.453 S 91.6 4.8 NA NA NA
GLY E:48 E:366 34.0 0.453 S 91.7 5.1 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLY A:48 A:366 35.0 0.467 S 84.0 20.5 20.0 0.267 0.2 B:Q19KF7:0.2
 HOH
 3.149
 O
 O
GLY C:48 E:366 41.0 0.547 S 84.9 20.0 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLY A:48 A:366 39.0 0.52 S 87.5 17.1 NA NA NA
GLY B:48 B:366 39.0 0.52 S 86.0 17.8 25.0 0.333 0.187 C:Q19KF7:0.187
GLY E:48 E:366 39.0 0.52 S 85.5 18.3 NA NA NA
GLY F:48 F:366 46.0 0.613 S 86.8 18.6 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 GLY A:46 A:366 42.0 0.56 S 88.7 -7.4 24.0 0.32 0.24 D:Q9JXV4:0.24
 HOH
 4.758
 O
 O
GLY B:46 B:366 36.0 0.48 S 97.5 -18.3 NA NA NA
GLY E:46 E:366 38.0 0.507 S 90.9 -17.4 NA NA NA
GLY G:46 G:366 39.0 0.52 S 94.1 -19.2 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 GLY A:46 A:366 40.0 0.533 S 96.8 -19.5 31.0 0.413 0.12 D:Q9JXV4:0.12
 HOH
 6.264
 C
 O
GLY B:46 B:366 40.0 0.533 S 94.7 -18.2 NA NA NA
GLY E:46 E:366 43.0 0.573 S 87.6 9.4 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLY A:366 A:366 39.0 0.52 S 78.2 8.6