Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196658691 . G A CCDS1385.1:NM_000186.3:c.1106tGg>tAg_NP_000177.2:p.369W>* Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 TRP A:50 A:369 103.0 0.404 E -150.1 148.3 103.0 0.404 0.0 HOH
 4.343
 CD1
 O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 TRP A:50 A:369 106.0 0.416 E -143.0 157.5 106.0 0.416 0.0 GOL
 3.495
 CD2
 O2
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 TRP A:51 A:369 101.0 0.396 E -147.4 152.8 19.0 0.075 0.321 D:Q9JXV4:0.322
 HOH
 2.891
 NE1
 O
TRP B:51 B:369 103.0 0.404 E -147.7 153.2 NA NA NA
TRP E:51 E:369 102.0 0.4 E -147.6 153.2 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 TRP A:51 A:369 103.0 0.404 E -141.0 154.5 17.0 0.067 0.337 D:Q9JXV4:0.337
 EDO
EDO
HOH
 8.541
5.728
3.156
 CZ3
CH2
O
 O2
C1
O
TRP B:51 B:369 103.0 0.404 E -141.6 154.8 NA NA NA
TRP E:51 E:369 104.0 0.408 E -141.4 154.4 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 TRP A:51 A:369 100.0 0.392 E -140.7 160.2 16.0 0.063 0.329 B:Q19KF7:0.329
 EDO
HOH
 7.966
4.182
 CZ3
CH2
 O1
O
TRP C:51 E:369 95.0 0.373 E -141.2 158.7 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 TRP A:51 A:369 100.0 0.392 E -143.9 159.2 NA NA NA
TRP B:51 B:369 100.0 0.392 E -144.0 159.1 17.0 0.067 0.325 C:Q19KF7:0.325
 HOH
 8.268
 CZ3
 O
TRP E:51 E:369 97.0 0.38 E -145.3 160.3 NA NA NA
TRP F:51 F:369 99.0 0.388 E -145.0 158.5 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 TRP A:49 A:369 111.0 0.435 E -140.9 154.8 15.0 0.059 0.376 D:Q9JXV4:0.376
 HOH
 2.776
 O
 O
TRP B:49 B:369 112.0 0.439 E -141.2 148.3 NA NA NA
TRP E:49 E:369 115.0 0.451 E -143.3 149.9 NA NA NA
TRP G:49 G:369 113.0 0.443 E -141.2 151.8 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 TRP A:49 A:369 105.0 0.412 E -138.6 148.4 17.0 0.067 0.345 D:Q9JXV4:0.345
 HOH
 2.441
 O
 O
TRP B:49 B:369 107.0 0.42 E -148.6 154.4 NA NA NA
TRP E:49 E:369 91.0 0.357 E -148.4 163.3 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 TRP A:369 A:369 106.0 0.416 E -151.4 153.7