Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196659255 . C A CCDS1385.1:NM_000186.3:c.1222Cag>Aag_NP_000177.2:p.408Q>K Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 GLN A:89 A:408 56.0 0.311 T -47.8 140.4 56.0 0.311 0.0 SO4
HOH
 6.210
3.331
 N
NE2
 O1
O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 GLN A:89 A:408 56.0 0.311 T -46.5 136.2 56.0 0.311 0.0 SO4
HOH
 6.021
4.276
 N
NE2
 O1
O
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLN A:90 A:408 58.0 0.322 T -47.6 130.8 58.0 0.322 0.0 HOH
 2.744
 OE1
 O
GLN B:90 B:408 56.0 0.311 T -50.9 129.1 NA NA NA
GLN E:90 E:408 50.0 0.278 T -51.8 125.0 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLN A:90 A:408 58.0 0.322 T -54.2 126.6 58.0 0.322 0.0 HOH
 7.034
 OE1
 O
GLN B:90 B:408 61.0 0.339 T -36.5 131.1 NA NA NA
GLN E:90 E:408 51.0 0.283 T -45.1 124.2 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLN A:90 A:408 64.0 0.356 T -42.7 127.8 64.0 0.356 0.0 HOH
 2.654
 OE1
 O
GLN C:90 E:408 58.0 0.322 T -43.6 128.8 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 GLN A:90 A:408 64.0 0.356 T -42.4 128.8 NA NA NA
GLN B:90 B:408 65.0 0.361 T -42.0 128.3 65.0 0.361 0.0
GLN E:90 E:408 60.0 0.333 T -44.1 130.5 NA NA NA
GLN F:90 F:408 55.0 0.306 T -44.1 129.4 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 GLN A:88 A:408 60.0 0.333 T -44.0 132.4 60.0 0.333 0.0 HOH
 3.632
 NE2
 O
GLN B:88 B:408 57.0 0.317 T -51.2 130.9 NA NA NA
GLN E:88 E:408 55.0 0.306 T -52.9 132.0 NA NA NA
GLN G:88 G:408 58.0 0.322 T -49.6 136.6 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 GLN A:88 A:408 52.0 0.289 T -51.2 124.0 52.0 0.289 0.0 HOH
 2.691
 OE1
 O
GLN B:88 B:408 53.0 0.294 T -54.5 137.1 NA NA NA
GLN E:88 E:408 54.0 0.3 T -53.5 123.4 NA NA NA
2jgw 1 P08603 100.0 2e-36 NMR
 2007-03-20 GLN A:23 A:408 69.0 0.383 T -49.8 118.9 69.0 0.383 0.0
2jgx 1 P08603 98.36 1e-35 NMR
 2007-03-20 GLN A:23 A:408 59.0 0.328 S -61.1 133.0 59.0 0.328 0.0
6atg 1 A0A024R962 100.0 5e-35 X-RAY
 2018-09-12 GLN A:23 A:390 98.0 0.544 T -53.4 135.3 98.0 0.544 0.0 HOH
 2.874
 N
 O
GLN D:23 D:390 68.0 0.378 T -51.2 133.6 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLN A:408 A:408 47.0 0.261 T -46.9 135.0