Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196659263 . A C CCDS1385.1:NM_000186.3:c.1230aaA>aaC_NP_000177.2:p.410K>N Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 LYS A:91 A:410 112.0 0.56 -88.8 137.7 112.0 0.56 0.0 SO4
SO4
SO4
HOH
 9.884
3.519
7.811
4.156
 CD
CE
NZ
CA
 O1
O4
O4
O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 LYS A:91 A:410 111.0 0.555 -86.9 139.4 111.0 0.555 0.0 SO4
SO4
SO4
HOH
 9.665
3.293
8.101
7.589
 NZ
NZ
NZ
NZ
 O4
O2
O4
O
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 LYS A:92 A:410 133.0 0.665 -83.2 144.2 133.0 0.665 0.0 HOH
 7.687
 NZ
 O
LYS B:92 B:410 104.0 0.52 -83.2 140.9 NA NA NA
LYS E:92 E:410 124.0 0.62 -85.4 144.3 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 LYS A:92 A:410 136.0 0.68 -75.6 141.7 136.0 0.68 0.0
LYS B:92 B:410 121.0 0.605 -58.9 137.2 NA NA NA
LYS E:92 E:410 143.0 0.715 -90.0 142.8 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 LYS A:92 A:410 140.0 0.7 -74.7 144.1 140.0 0.7 0.0 HOH
 3.671
 CA
 O
LYS C:92 E:410 145.0 0.725 -74.7 143.0 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 LYS A:92 A:410 139.0 0.695 -75.2 144.1 NA NA NA
LYS B:92 B:410 139.0 0.695 -75.2 143.9 139.0 0.695 0.0
LYS E:92 E:410 92.0 0.46 -76.7 143.8 NA NA NA
LYS F:92 F:410 126.0 0.63 -76.4 144.5 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 LYS A:90 A:410 91.0 0.455 -76.4 136.9 91.0 0.455 0.0 HOH
 2.753
 NZ
 O
LYS B:90 B:410 83.0 0.415 -85.1 141.3 NA NA NA
LYS E:90 E:410 94.0 0.47 -77.9 133.8 NA NA NA
LYS G:90 G:410 91.0 0.455 -77.9 138.7 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 LYS A:90 A:410 104.0 0.52 -80.5 151.2 104.0 0.52 0.0 HOH
 2.838
 CD
 O
LYS B:90 B:410 94.0 0.47 -73.5 145.3 NA NA NA
LYS E:90 E:410 84.0 0.42 -73.8 124.9 NA NA NA
2jgw 1 P08603 100.0 2e-36 NMR
 2007-03-20 LYS A:25 A:410 117.0 0.585 -97.6 160.8 117.0 0.585 0.0
2jgx 1 P08603 98.36 1e-35 NMR
 2007-03-20 LYS A:25 A:410 97.0 0.485 E -127.7 163.7 97.0 0.485 0.0
6atg 1 A0A024R962 100.0 5e-35 X-RAY
 2018-09-12 LYS A:25 A:392 95.0 0.475 -67.8 137.2 95.0 0.475 0.0 HOH
 3.795
 N
 O
LYS D:25 D:392 100.0 0.5 -77.6 132.7 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 LYS A:410 A:410 124.0 0.62 -69.4 114.7