Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196659324 . T A CCDS1385.1:NM_000186.3:c.1291Tgt>Agt_NP_000177.2:p.431C>S Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 CYS A:112 A:431 0.0 0.0 E -84.6 110.6 0.0 0.0 0.0 SO4
HOH
 7.967
4.981
 CB
O
 O4
O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 CYS A:112 A:431 0.0 0.0 E -88.3 116.4 0.0 0.0 0.0 SO4
HOH
 7.941
5.272
 CB
O
 O4
O
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 CYS A:113 A:431 0.0 0.0 E -83.4 103.1 0.0 0.0 0.0 HOH
 6.977
 SG
 O
CYS B:113 B:431 0.0 0.0 E -78.3 98.3 NA NA NA
CYS E:113 E:431 0.0 0.0 E -78.9 111.4 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 CYS A:113 A:431 0.0 0.0 E -83.5 111.0 0.0 0.0 0.0
CYS B:113 B:431 0.0 0.0 E -76.7 102.6 NA NA NA
CYS E:113 E:431 0.0 0.0 E -79.6 106.3 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 CYS A:113 A:431 0.0 0.0 E -79.0 110.1 0.0 0.0 0.0 HOH
 4.854
 O
 O
CYS C:113 E:431 0.0 0.0 E -74.8 112.7 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 CYS A:113 A:431 0.0 0.0 E -80.9 106.3 NA NA NA
CYS B:113 B:431 0.0 0.0 E -81.3 105.9 0.0 0.0 0.0
CYS E:113 E:431 1.0 0.007 E -80.4 107.2 NA NA NA
CYS F:113 F:431 1.0 0.007 E -79.7 107.4 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 CYS A:111 A:431 1.0 0.007 E -77.4 111.1 1.0 0.007 0.0 HOH
 2.897
 O
 O
CYS B:111 B:431 1.0 0.007 E -79.0 105.9 NA NA NA
CYS E:111 E:431 0.0 0.0 E -77.9 107.9 NA NA NA
CYS G:111 G:431 1.0 0.007 E -80.5 104.1 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 CYS A:111 A:431 1.0 0.007 E -82.3 101.1 1.0 0.007 0.0 HOH
 7.634
 N
 O
CYS B:111 B:431 0.0 0.0 E -79.9 95.8 NA NA NA
CYS E:111 E:431 1.0 0.007 E -87.2 98.6 NA NA NA
2jgw 1 P08603 100.0 2e-36 NMR
 2007-03-20 CYS A:46 A:431 0.0 0.0 B -85.1 83.1 0.0 0.0 0.0
2jgx 1 P08603 98.36 1e-35 NMR
 2007-03-20 CYS A:46 A:431 0.0 0.0 E -66.8 113.5 0.0 0.0 0.0
6atg 1 A0A024R962 100.0 5e-35 X-RAY
 2018-09-12 CYS A:46 A:413 1.0 0.007 E -72.5 118.2 1.0 0.007 0.0 HOH
 5.781
 C
 O
CYS D:46 D:413 1.0 0.007 E -75.2 118.5 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 CYS A:431 A:431 0.0 0.0 E -71.4 107.6