Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196659342 . T A CCDS1385.1:NM_000186.3:c.1309Tct>Act_NP_000177.2:p.437S>T Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
2uwn 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 SER A:118 A:437 54.0 0.47 E -139.0 109.0 54.0 0.47 0.0 HOH
 2.753
 O
 O
2v8e 1 P08603 100.0 2e-127 X-RAY
 2007-10-02 SER A:118 A:437 50.0 0.435 E -137.4 111.4 50.0 0.435 0.0 HOH
 7.001
 O
 O
4ayd 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 SER A:119 A:437 62.0 0.539 E -136.5 108.6 62.0 0.539 0.0 HOH
 5.779
 N
 O
SER B:119 B:437 59.0 0.513 E -136.7 108.3 NA NA NA
SER E:119 E:437 61.0 0.53 E -136.5 108.5 NA NA NA
4aye 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 SER A:119 A:437 61.0 0.53 E -132.5 109.6 61.0 0.53 0.0
SER B:119 B:437 62.0 0.539 E -143.2 111.2 NA NA NA
SER E:119 E:437 58.0 0.504 E -124.8 109.8 NA NA NA
4ayi 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 SER A:119 A:437 64.0 0.557 E -133.7 111.8 64.0 0.557 0.0 HOH
 4.215
 CB
 O
SER C:119 E:437 64.0 0.557 E -133.7 112.1 NA NA NA
4aym 1 P08603 100.0 1e-82 X-RAY
 2012-11-07 SER A:119 A:437 57.0 0.496 E -132.8 113.3 NA NA NA
SER B:119 B:437 64.0 0.557 E -133.4 113.7 64.0 0.557 0.0
SER E:119 E:437 58.0 0.504 E -134.2 113.6 NA NA NA
SER F:119 F:437 64.0 0.557 E -134.2 114.2 NA NA NA
2w80 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 SER A:117 A:437 64.0 0.557 E -132.6 112.8 64.0 0.557 0.0 HOH
 4.828
 N
 O
SER B:117 B:437 59.0 0.513 E -133.4 112.6 NA NA NA
SER E:117 E:437 60.0 0.522 E -136.6 111.1 NA NA NA
SER G:117 G:437 58.0 0.504 E -142.6 110.7 NA NA NA
2w81 1 P08603 100.0 1e-82 X-RAY
 2009-03-03 SER A:117 A:437 59.0 0.513 E -142.7 112.2 59.0 0.513 0.0
SER B:117 B:437 59.0 0.513 E -145.9 114.3 NA NA NA
SER E:117 E:437 58.0 0.504 E -142.6 113.1 NA NA NA
2jgw 1 P08603 100.0 2e-36 NMR
 2007-03-20 SER A:52 A:437 46.0 0.4 S -69.8 -51.3 46.0 0.4 0.0
2jgx 1 P08603 98.36 1e-35 NMR
 2007-03-20 SER A:52 A:437 58.0 0.504 T -40.3 -60.6 58.0 0.504 0.0
6atg 1 A0A024R962 100.0 5e-35 X-RAY
 2018-09-12 SER A:52 A:419 57.0 0.496 E -128.9 120.3 57.0 0.496 0.0 HOH
 2.712
 O
 O
SER D:52 D:419 52.0 0.452 E -139.4 118.0 NA NA NA

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 SER A:437 A:437 64.0 0.557 E -134.6 126.1