Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196714958 . A C CCDS1385.1:NM_000186.3:c.3322Aaa>Caa_NP_000177.2:p.1108K>Q Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 LYS A:65 X:1108 81.0 0.405 -67.9 155.2 81.0 0.405 0.0 GOL
PO4
HOH
 5.441
6.515
2.650
 N
CG
O
 O3
O3
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 LYS B:10 B:1108 113.0 0.565 -94.1 137.5 113.0 0.565 0.0 HOH
 3.521
 CE
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 LYS A:10 A:1108 130.0 0.65 -71.7 156.7 94.0 0.47 0.18 A:P08603:0.005
A:P08603:0.175
 SO4
SO4
SO4
HOH
 3.172
4.999
8.096
2.674
 N
O
NZ
O
 O2
O2
O2
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 LYS A:10 A:1108 143.0 0.715 -65.9 153.2 103.0 0.515 0.2 A:P08603:0.19
A:P08603:0.015
 SO4
HOH
 3.083
2.737
 N
O
 O3
O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 LYS D:5 D:1108 138.0 0.69 -79.3 145.9 138.0 0.69 0.0
LYS E:5 E:1108 102.0 0.51 -77.6 141.9 NA NA NA
LYS F:5 F:1108 117.0 0.585 -75.7 155.1 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 LYS C:10 NA:NA DO NA DO DO DO NA NA NA
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 LYS B:6 B:1108 130.0 0.65 -88.4 148.7 130.0 0.65 0.0
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 LYS D:6 D:1108 145.0 0.725 -78.5 150.3 NA NA NA
LYS E:6 E:1108 149.0 0.745 -84.0 148.8 NA NA NA
LYS F:6 F:1108 141.0 0.705 -94.2 162.5 141.0 0.705 0.0 HOH
 3.761
 NZ
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 LYS A:6 F:1108 87.0 NA 360.0 121.4 87.0 NA NA
LYS C:6 D:1108 137.0 0.685 -72.6 146.8 NA NA NA
LYS E:6 E:1108 143.0 0.715 -64.9 141.7 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 LYS D:6 D:1108 113.0 0.565 -65.2 151.7 NA NA NA
LYS E:6 E:1108 140.0 0.7 -64.7 151.9 140.0 0.7 0.0 HOH
 3.813
 CB
 O
LYS F:6 NA:NA DO NA DO DO DO NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 LYS A:2 A:1108 148.0 0.74 -63.9 152.4 109.0 0.545 0.195 A:P08603:0.185
A:P08603:0.01
 HOH
 2.555
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 LYS A:6 A:1108 148.0 0.74 -65.5 152.7 148.0 0.74 0.0 HOH
 2.640
 O
 O
LYS B:6 B:1108 126.0 0.63 -81.8 157.4 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 LYS D:6 D:1108 148.0 0.74 -61.0 149.3 148.0 0.74 0.0 HOH
 5.219
 O
 O
LYS E:6 E:1108 148.0 0.74 -70.2 152.2 NA NA NA
LYS F:6 F:1108 168.0 0.84 -96.4 132.3 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 LYS A:3 A:207 146.0 0.73 -72.1 159.2 115.0 0.575 0.155 B:Q03591:0.155
 SO4
 3.485
 N
 O2
LYS B:3 B:207 138.0 0.69 -84.9 171.2 102.0 0.51 0.18 A:Q03591:0.18
 SO4
 2.440
 N
 O4

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 LYS A:1108 A:1108 107.0 0.535 -84.4 135.8