Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196714965 . G A CCDS1385.1:NM_000186.3:c.3329gGg>gAg_NP_000177.2:p.1110G>E Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 GLY A:67 X:1110 32.0 0.427 -82.7 -169.7 32.0 0.427 0.0 GOL
PO4
HOH
 9.601
8.630
2.890
 N
O
N
 O3
O4
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 GLY B:12 B:1110 36.0 0.48 -90.4 -162.9 36.0 0.48 0.0 HOH
 2.953
 N
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 GLY A:12 A:1110 33.0 0.44 -88.7 -165.6 10.0 0.133 0.307 A:P08603:0.307
 SO4
SO4
HOH
 8.267
2.828
3.841
 N
N
CA
 O4
O2
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 GLY A:12 A:1110 34.0 0.453 -88.8 -164.8 10.0 0.133 0.32 A:P08603:0.32
 SO4
HOH
 8.193
3.070
 N
N
 O2
O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 GLY D:7 D:1110 36.0 0.48 -81.7 -172.7 36.0 0.48 0.0
GLY E:7 E:1110 37.0 0.493 -82.8 -171.6 NA NA NA
GLY F:7 F:1110 36.0 0.48 -82.4 -171.6 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 GLY C:12 C:1110 29.0 0.387 -86.2 -142.3 29.0 0.387 0.0 HOH
 4.114
 N
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 GLY B:8 B:1110 33.0 0.44 -76.9 -164.1 33.0 0.44 0.0 HOH
 6.795
 C
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 GLY D:8 D:1110 33.0 0.44 -85.1 -162.6 NA NA NA
GLY E:8 E:1110 37.0 0.493 -75.9 -161.5 NA NA NA
GLY F:8 F:1110 17.0 0.227 88.3 174.6 17.0 0.227 0.0 HOH
 8.562
 O
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 GLY A:8 F:1110 40.0 0.533 -80.5 -171.2 40.0 0.533 0.0 HOH
 9.106
 O
 O
GLY C:8 D:1110 33.0 0.44 -86.7 -159.1 NA NA NA
GLY E:8 E:1110 37.0 0.493 -76.1 -165.3 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 GLY D:8 D:1110 32.0 0.427 -90.7 -160.4 NA NA NA
GLY E:8 E:1110 33.0 0.44 -90.2 -157.1 33.0 0.44 0.0 HOH
 3.363
 C
 O
GLY F:8 F:1110 33.0 0.44 -91.0 -158.4 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 GLY A:4 A:1110 35.0 0.467 -88.5 -168.1 9.0 0.12 0.347 A:P08603:0.347
 HOH
 3.022
 N
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 GLY A:8 A:1110 38.0 0.507 -76.5 -169.7 38.0 0.507 0.0 HOH
 3.189
 N
 O
GLY B:8 B:1110 36.0 0.48 -79.3 -174.4 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 GLY D:8 D:1110 33.0 0.44 -79.0 -162.3 33.0 0.44 0.0 HOH
 2.829
 N
 O
GLY E:8 E:1110 35.0 0.467 -80.2 -162.7 NA NA NA
GLY F:8 F:1110 39.0 0.52 -73.2 174.7 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 GLY A:5 A:209 35.0 0.467 -85.6 -167.9 0.0 0.0 0.467 B:Q03591:0.467
 SO4
 7.499
 N
 O2
GLY B:5 B:209 37.0 0.493 -67.8 -167.0 11.0 0.147 0.346 A:Q03591:0.347
 SO4
 7.247
 N
 O4

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLY A:1110 A:1110 37.0 0.493 -71.8 -173.8