Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196714985 . A C CCDS1385.1:NM_000186.3:c.3349Aat>Cat_NP_000177.2:p.1117N>H Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 ASN A:74 X:1117 42.0 0.263 T 59.2 27.8 42.0 0.263 0.0 GOL
HOH
 7.229
2.564
 O
OD1
 C3
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 ASN B:19 B:1117 45.0 0.281 T 59.4 26.0 45.0 0.281 0.0 HOH
 2.625
 OD1
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 ASN A:19 A:1117 63.0 0.394 T 60.5 26.0 9.0 0.056 0.338 A:P08603:0.338
 HOH
 2.872
 ND2
 O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 ASN A:19 A:1117 57.0 0.356 T 61.9 21.9 4.0 0.025 0.331 A:P08603:0.331
 HOH
 2.913
 ND2
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 ASN D:14 D:1117 44.0 0.275 T 62.3 39.3 32.0 0.2 0.075 A:P01024:0.075
ASN E:14 E:1117 46.0 0.287 T 62.3 37.7 NA NA NA
ASN F:14 F:1117 44.0 0.275 T 61.9 37.5 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 ASN C:19 C:1117 65.0 0.406 T 58.9 27.9 38.0 0.237 0.169 A:P01024:0.169
 HOH
 2.778
 N
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 ASN B:15 B:1117 62.0 0.388 T 60.9 27.6 62.0 0.388 0.0 HOH
 8.824
 CB
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 ASN D:15 D:1117 40.0 0.25 T 58.9 27.6 NA NA NA
ASN E:15 E:1117 48.0 0.3 T 54.9 34.2 NA NA NA
ASN F:15 F:1117 45.0 0.281 T 58.7 28.3 33.0 0.206 0.075 B:P01024:0.075
 HOH
 2.848
 ND2
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 ASN A:15 F:1117 43.0 0.269 T 49.2 33.3 31.0 0.194 0.075 D:P01024:0.075
 HOH
 2.851
 ND2
 O
ASN C:15 D:1117 40.0 0.25 T 64.2 24.6 NA NA NA
ASN E:15 E:1117 49.0 0.306 T 54.0 35.9 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 ASN D:15 D:1117 45.0 0.281 T 60.9 30.6 NA NA NA
ASN E:15 E:1117 46.0 0.287 T 58.6 34.7 31.0 0.194 0.093 A:P01024:0.094
 HOH
 2.778
 ND2
 O
ASN F:15 F:1117 45.0 0.281 T 59.6 31.8 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 ASN A:11 A:1117 46.0 0.287 T 59.7 24.6 1.0 0.006 0.281 A:P08603:0.281
 HOH
 2.913
 ND2
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 ASN A:15 A:1117 49.0 0.306 T 64.2 24.1 49.0 0.306 0.0 GOL
HOH
 3.529
2.810
 ND2
OD1
 O3
O
ASN B:15 B:1117 49.0 0.306 T 65.7 18.8 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 ASN D:15 D:1117 42.0 0.263 T 59.1 29.8 42.0 0.263 0.0 HOH
 2.745
 OD1
 O
ASN E:15 E:1117 48.0 0.3 T 51.0 37.5 NA NA NA
ASN F:15 F:1117 47.0 0.294 T 57.0 31.7 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 ASN A:12 A:216 54.0 0.338 T 55.1 24.6 4.0 0.025 0.313 B:Q03591:0.312
 SO4
SO4
 8.146
8.862
 C
OD1
 O2
O1
ASN B:12 B:216 52.0 0.325 T 61.3 42.2 3.0 0.019 0.306 A:Q03591:0.306
 SO4
SO4
 8.450
8.411
 OD1
C
 O2
O3

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 ASN A:1117 A:1117 47.0 0.294 T 53.6 25.6