Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196714992 . A C CCDS1385.1:NM_000186.3:c.3356gAc>gCc_NP_000177.2:p.1119D>A Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 ASP A:76 X:1119 105.0 0.7 E -153.9 167.1 105.0 0.7 0.0 GOL
HOH
 9.174
6.553
 N
O
 C3
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 ASP B:21 B:1119 112.0 0.747 E -164.6 163.1 112.0 0.747 0.0 HOH
 2.801
 OD1
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 ASP A:21 A:1119 122.0 0.813 E -147.1 156.5 70.0 0.467 0.346 A:P08603:0.153
A:P08603:0.193
 HOH
 2.834
 OD2
 O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 ASP A:21 A:1119 79.0 0.527 E -146.6 147.9 33.0 0.22 0.307 A:P08603:0.167
A:P08603:0.147
 HOH
 2.477
 OD1
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 ASP D:16 D:1119 114.0 0.76 E -164.5 174.9 5.0 0.033 0.727 A:P01024:0.727
ASP E:16 E:1119 111.0 0.74 E -165.6 173.5 NA NA NA
ASP F:16 F:1119 109.0 0.727 E -164.6 174.0 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 GLY C:21 C:1119 32.0 0.427 E -162.2 161.7 13.0 0.173 0.254 A:P01024:0.253
 HOH
 3.132
 CA
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 GLY B:17 B:1119 33.0 0.44 E -150.9 165.8 33.0 0.44 0.0 HOH
 5.918
 O
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 ASP D:17 D:1119 111.0 0.74 E -159.0 168.0 NA NA NA
ASP E:17 E:1119 112.0 0.747 E -155.2 173.6 NA NA NA
ASP F:17 F:1119 113.0 0.753 E -162.1 171.3 9.0 0.06 0.693 B:P01024:0.693
 HOH
 2.644
 OD1
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 ASP A:17 F:1119 112.0 0.747 E -168.2 173.8 11.0 0.073 0.674 D:P01024:0.673
 HOH
 6.906
 O
 O
ASP C:17 D:1119 117.0 0.78 E -160.9 170.1 NA NA NA
ASP E:17 E:1119 112.0 0.747 E -158.9 173.7 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 ASP D:17 D:1119 113.0 0.753 E -159.0 173.4 NA NA NA
ASP E:17 E:1119 109.0 0.727 E -159.8 176.9 3.0 0.02 0.707 A:P01024:0.707
 HOH
 2.644
 OD1
 O
ASP F:17 F:1119 111.0 0.74 E -161.6 177.2 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 ASP A:13 A:1119 100.0 0.667 E -147.8 152.4 47.0 0.313 0.354 A:P08603:0.207
A:P08603:0.153
 HOH
 2.724
 CG
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 ASP A:17 A:1119 104.0 0.693 E -167.4 176.9 104.0 0.693 0.0 HOH
 2.616
 OD2
 O
ASP B:17 B:1119 84.0 0.56 E -160.8 151.3 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 ASP D:17 D:1119 110.0 0.733 E -161.1 171.9 110.0 0.733 0.0 HOH
 3.205
 OD1
 O
ASP E:17 E:1119 115.0 0.767 E -150.6 178.2 NA NA NA
ASP F:17 F:1119 110.0 0.733 E -170.2 171.7 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 ASP A:14 A:218 90.0 0.6 E -120.2 170.9 80.0 0.533 0.067 B:Q03591:0.067
 SO4
 3.763
 CB
 O2
ASP B:14 B:218 91.0 0.607 E -131.0 163.5 76.0 0.507 0.1 A:Q03591:0.1
 SO4
 3.789
 CA
 O3

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 ASP A:1119 A:1119 113.0 0.753 E -137.6 163.1