Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196715034 . C A CCDS1385.1:NM_000186.3:c.3398tCa>tAa_NP_000177.2:p.1133S>* Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 SER A:90 X:1133 57.0 0.496 E -133.4 154.3 57.0 0.496 0.0 PO4
HOH
 6.334
2.937
 N
O
 O1
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 SER B:35 B:1133 48.0 0.417 E -131.0 153.1 48.0 0.417 0.0 HOH
 4.821
 O
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 SER A:35 A:1133 51.0 0.443 E -144.8 155.3 51.0 0.443 0.0 SO4
HOH
 5.741
2.713
 OG
O
 O3
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 SER A:35 A:1133 53.0 0.461 E -139.3 155.1 53.0 0.461 0.0 HOH
 2.761
 O
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 SER D:30 D:1133 49.0 0.426 E -137.2 143.6 49.0 0.426 0.0
SER E:30 E:1133 57.0 0.496 E -139.1 140.6 NA NA NA
SER F:30 F:1133 44.0 0.383 E -136.6 143.7 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 SER C:35 C:1133 83.0 0.722 E -126.2 134.3 83.0 0.722 0.0 HOH
 4.805
 O
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 SER B:31 B:1133 52.0 0.452 E -113.5 158.2 52.0 0.452 0.0 HOH
 7.446
 OG
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 SER D:31 D:1133 50.0 0.435 E -139.5 153.4 NA NA NA
SER E:31 E:1133 48.0 0.417 E -136.5 156.0 NA NA NA
SER F:31 F:1133 57.0 0.496 E -137.1 151.2 57.0 0.496 0.0 HOH
 3.575
 O
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 SER A:31 F:1133 53.0 0.461 E -114.7 162.3 53.0 0.461 0.0 HOH
 5.244
 O
 O
SER C:31 D:1133 57.0 0.496 E -146.3 158.1 NA NA NA
SER E:31 E:1133 48.0 0.417 E -125.6 158.2 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 SER D:31 D:1133 52.0 0.452 E -140.1 158.1 NA NA NA
SER E:31 E:1133 47.0 0.409 E -139.1 159.2 47.0 0.409 0.0 HOH
 5.084
 O
 O
SER F:31 F:1133 64.0 0.557 E -140.5 159.0 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 SER A:27 A:1133 61.0 0.53 E -137.9 157.7 61.0 0.53 0.0 HOH
 2.774
 OG
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 SER A:31 A:1133 46.0 0.4 E -137.2 164.7 46.0 0.4 0.0 HOH
 2.963
 OG
 O
SER B:31 B:1133 61.0 0.53 E -132.3 155.3 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 SER D:31 D:1133 55.0 0.478 E -149.7 149.7 55.0 0.478 0.0 HOH
 5.071
 O
 O
SER E:31 E:1133 57.0 0.496 E -131.6 149.2 NA NA NA
SER F:31 F:1133 55.0 0.478 E -141.2 143.4 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 SER A:28 A:232 50.0 0.435 E -139.7 145.2 50.0 0.435 0.0
SER B:28 B:232 65.0 0.565 E -128.3 144.2 65.0 0.565 0.0 SO4
 4.449
 O
 O1

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 SER A:1133 A:1133 53.0 0.461 E -126.6 136.5