Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196715044 . C A CCDS1385.1:NM_000186.3:c.3408taC>taA_NP_000177.2:p.1136Y>* Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 TYR A:93 X:1136 8.0 0.035 E -114.6 157.5 8.0 0.035 0.0 GOL
HOH
 7.346
2.740
 O
O
 O3
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 TYR B:38 B:1136 4.0 0.017 E -107.3 155.0 4.0 0.017 0.0 HOH
 4.657
 O
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 TYR A:38 A:1136 5.0 0.022 E -104.0 153.5 5.0 0.022 0.0 SO4
SO4
HOH
 9.974
9.682
2.610
 N
OH
O
 O4
O4
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 TYR A:38 A:1136 5.0 0.022 E -104.3 153.9 5.0 0.022 0.0 HOH
 2.647
 O
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 TYR D:33 D:1136 6.0 0.026 E -106.9 151.3 6.0 0.026 0.0
TYR E:33 E:1136 4.0 0.017 E -107.0 150.0 NA NA NA
TYR F:33 F:1136 5.0 0.022 E -105.9 150.6 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 TYR C:38 C:1136 9.0 0.039 E -111.9 152.3 9.0 0.039 0.0 HOH
 4.774
 CE2
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 TYR B:34 B:1136 4.0 0.017 E -115.4 150.6 4.0 0.017 0.0 HOH
 2.558
 O
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 TYR D:34 D:1136 6.0 0.026 E -103.7 150.9 NA NA NA
TYR E:34 E:1136 5.0 0.022 E -103.6 154.4 NA NA NA
TYR F:34 F:1136 4.0 0.017 E -110.6 154.6 4.0 0.017 0.0 HOH
 2.935
 O
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 TYR A:34 F:1136 4.0 0.017 E -101.9 163.6 4.0 0.017 0.0 HOH
 5.453
 N
 O
TYR C:34 D:1136 7.0 0.03 E -107.6 149.2 NA NA NA
TYR E:34 E:1136 2.0 0.009 E -101.9 157.1 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 TYR D:34 D:1136 7.0 0.03 E -104.6 153.8 NA NA NA
TYR E:34 E:1136 4.0 0.017 E -102.7 155.0 4.0 0.017 0.0 HOH
 3.934
 CE2
 O
TYR F:34 F:1136 4.0 0.017 E -99.9 154.9 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 TYR A:30 A:1136 5.0 0.022 E -103.4 154.3 5.0 0.022 0.0 HOH
 2.632
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 TYR A:34 A:1136 2.0 0.009 E -99.5 150.4 2.0 0.009 0.0 HOH
 2.763
 O
 O
TYR B:34 B:1136 5.0 0.022 E -114.4 158.1 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 TYR D:34 D:1136 3.0 0.013 E -103.1 154.1 3.0 0.013 0.0 HOH
 3.780
 CE2
 O
TYR E:34 E:1136 7.0 0.03 E -101.7 158.1 NA NA NA
TYR F:34 F:1136 4.0 0.017 E -104.5 167.9 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 TYR A:31 A:235 5.0 0.022 E -91.8 144.2 5.0 0.022 0.0 SO4
 5.572
 CE1
 O1
TYR B:31 B:235 6.0 0.026 E -97.1 167.2 6.0 0.026 0.0 SO4
SO4
 4.965
7.823
 CE2
N
 O4
O1

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 TYR A:1136 A:1136 9.0 0.039 E -83.7 150.1