Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196715045 . C A CCDS1385.1:NM_000186.3:c.3409Caa>Aaa_NP_000177.2:p.1137Q>K Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 GLN A:94 X:1137 126.0 0.7 E -130.3 135.7 126.0 0.7 0.0 HOH
 6.973
 O
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 GLN B:39 B:1137 128.0 0.711 E -133.4 153.0 128.0 0.711 0.0 HOH
 3.547
 CA
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 GLN A:39 A:1137 129.0 0.717 E -131.4 147.8 44.0 0.244 0.473 A:P08603:0.472
 HOH
 3.124
 OE1
 O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 GLN A:39 A:1137 118.0 0.656 E -131.3 144.1 39.0 0.217 0.439 A:P08603:0.439
 HOH
 2.738
 NE2
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 GLN D:34 D:1137 133.0 0.739 E -140.0 127.1 60.0 0.333 0.406 A:P01024:0.406
GLN E:34 E:1137 132.0 0.733 E -139.0 127.5 NA NA NA
GLN F:34 F:1137 133.0 0.739 E -139.4 128.2 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 GLN C:39 C:1137 120.0 0.667 E -132.6 151.9 53.0 0.294 0.373 A:P01024:0.372
 HOH
 3.909
 CA
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 GLN B:35 B:1137 136.0 0.756 E -128.1 143.7 136.0 0.756 0.0 HOH
 2.148
 OE1
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 GLN D:35 D:1137 133.0 0.739 E -129.9 137.9 NA NA NA
GLN E:35 E:1137 132.0 0.733 E -134.7 137.3 NA NA NA
GLN F:35 F:1137 125.0 0.694 E -135.2 141.2 58.0 0.322 0.372 B:P01024:0.372
 HOH
 2.899
 OE1
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 GLN A:35 F:1137 122.0 0.678 E -145.1 145.9 58.0 0.322 0.356 D:P01024:0.356
 HOH
 4.306
 OE1
 O
GLN C:35 D:1137 133.0 0.739 E -133.0 141.6 NA NA NA
GLN E:35 E:1137 130.0 0.722 E -138.9 136.1 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 GLN D:35 D:1137 135.0 0.75 E -135.7 138.6 NA NA NA
GLN E:35 E:1137 133.0 0.739 E -137.8 138.7 63.0 0.35 0.389 A:P01024:0.389
 HOH
 3.227
 OE1
 O
GLN F:35 F:1137 129.0 0.717 E -135.5 139.6 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 GLN A:31 A:1137 119.0 0.661 E -131.0 138.3 45.0 0.25 0.411 A:P08603:0.411
 HOH
 2.340
 NE2
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 GLN A:35 A:1137 133.0 0.739 E -129.8 143.2 133.0 0.739 0.0 HOH
 2.610
 NE2
 O
GLN B:35 B:1137 124.0 0.689 E -136.3 144.0 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 GLN D:35 D:1137 127.0 0.706 E -140.9 150.3 127.0 0.706 0.0 HOH
 3.312
 CA
 O
GLN E:35 E:1137 130.0 0.722 E -141.1 137.5 NA NA NA
GLN F:35 F:1137 116.0 0.644 E -154.5 128.6 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 GLN A:32 A:236 120.0 0.667 E -133.9 144.7 120.0 0.667 0.0 SO4
 8.138
 O
 O2
GLN B:32 B:236 121.0 0.672 E -154.2 128.4 121.0 0.672 0.0 SO4
 7.672
 O
 O3

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLN A:1137 A:1137 128.0 0.711 E -133.6 124.0