Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196715051 . C A CCDS1385.1:NM_000186.3:c.3415Cag>Aag_NP_000177.2:p.1139Q>K Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 GLN A:96 X:1139 101.0 0.561 -63.9 164.2 101.0 0.561 0.0 GOL
HOH
 3.395
3.578
 O
CA
 O2
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 GLN B:41 B:1139 102.0 0.567 -64.2 151.5 102.0 0.567 0.0 HOH
 3.731
 C
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 ALA A:41 A:1139 42.0 0.365 -58.5 154.0 33.0 0.287 0.078 A:P08603:0.026
A:P08603:0.052
 HOH
 3.100
 O
 O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 GLN A:41 A:1139 91.0 0.506 -58.2 157.7 14.0 0.078 0.428 A:P08603:0.283
A:P08603:0.144
A:P08603:0.05
 HOH
 3.040
 O
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 GLN D:36 D:1139 110.0 0.611 -63.5 168.4 7.0 0.039 0.572 A:P01024:0.572
GLN E:36 E:1139 112.0 0.622 -64.1 168.4 NA NA NA
GLN F:36 F:1139 113.0 0.628 -62.9 169.3 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 ALA C:41 C:1139 43.0 0.374 -65.0 165.6 11.0 0.096 0.278 A:P01024:0.278
 HOH
 3.007
 O
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 ALA B:37 B:1139 40.0 0.348 -69.3 177.6 40.0 0.348 0.0 HOH
 7.168
 O
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 GLN D:37 D:1139 105.0 0.583 -61.9 166.1 NA NA NA
GLN E:37 E:1139 113.0 0.628 -63.6 165.0 NA NA NA
GLN F:37 F:1139 111.0 0.617 -59.5 163.3 7.0 0.039 0.578 B:P01024:0.578
 HOH
 2.514
 OE1
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 GLN A:37 F:1139 110.0 0.611 -62.2 159.7 8.0 0.044 0.567 D:P01024:0.567
 HOH
 2.792
 NE2
 O
GLN C:37 D:1139 100.0 0.556 -66.2 158.3 NA NA NA
GLN E:37 E:1139 113.0 0.628 -68.3 167.6 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 GLN D:37 D:1139 114.0 0.633 -64.3 166.6 NA NA NA
GLN E:37 E:1139 113.0 0.628 -65.0 167.3 8.0 0.044 0.584 A:P01024:0.583
 HOH
 2.666
 OE1
 O
GLN F:37 F:1139 112.0 0.622 -65.0 166.5 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 GLN A:33 A:1139 77.0 0.428 -66.4 159.0 22.0 0.122 0.306 A:P08603:0.283
A:P08603:0.022
 HOH
 3.075
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 GLN A:37 A:1139 111.0 0.617 -59.9 158.6 111.0 0.617 0.0 GOL
HOH
 7.876
2.547
 OE1
OE1
 O3
O
GLN B:37 B:1139 82.0 0.456 -64.5 163.3 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 GLN D:37 D:1139 103.0 0.572 -64.8 162.9 103.0 0.572 0.0 HOH
 2.624
 NE2
 O
GLN E:37 E:1139 110.0 0.611 -66.5 164.7 NA NA NA
GLN F:37 F:1139 108.0 0.6 -62.9 160.6 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 GLN A:34 A:238 88.0 0.489 -53.4 156.9 50.0 0.278 0.211 B:Q03591:0.211
 SO4
SO4
 7.655
8.892
 OE1
CG
 O2
O1
GLN B:34 B:238 74.0 0.411 -61.2 152.2 35.0 0.194 0.217 A:Q03591:0.217
 SO4
SO4
 8.128
7.999
 CB
NE2
 O2
O3

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLN A:1139 A:1139 112.0 0.622 -55.9 158.4