Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196715063 . C A CCDS1385.1:NM_000186.3:c.3427Caa>Aaa_NP_000177.2:p.1143Q>K Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 GLN A:100 X:1143 68.0 0.378 E -116.2 125.0 68.0 0.378 0.0 GOL
GOL
HOH
 6.201
4.926
3.416
 OE1
N
N
 C1
O2
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 GLN B:45 B:1143 70.0 0.389 E -111.8 127.2 70.0 0.389 0.0 HOH
 3.166
 OE1
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 GLN A:45 A:1143 71.0 0.394 E -98.3 125.4 71.0 0.394 0.0 HOH
 2.785
 CG
 O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 GLN A:45 A:1143 72.0 0.4 E -99.6 124.4 72.0 0.4 0.0 HOH
 2.872
 OE1
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 GLN D:40 D:1143 72.0 0.4 E -91.0 117.0 62.0 0.344 0.056 G:Q45001:0.056
GLN E:40 E:1143 81.0 0.45 E -94.2 116.9 NA NA NA
GLN F:40 F:1143 80.0 0.444 E -104.7 116.7 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 GLN C:45 C:1143 75.0 0.417 E -118.0 116.1 75.0 0.417 0.0 HOH
 3.522
 N
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 GLN B:41 B:1143 78.0 0.433 E -107.9 125.5 68.0 0.378 0.055 A:E4QGX1:0.056
 HOH
 3.294
 N
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 GLN D:41 D:1143 73.0 0.406 E -113.8 124.2 NA NA NA
GLN E:41 E:1143 88.0 0.489 E -108.1 123.1 NA NA NA
GLN F:41 F:1143 84.0 0.467 E -113.4 119.8 84.0 0.467 0.0 HOH
 3.399
 N
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 GLN A:41 F:1143 66.0 0.367 E -112.0 117.6 66.0 0.367 0.0 HOH
 7.038
 O
 O
GLN C:41 D:1143 63.0 0.35 E -119.9 130.3 NA NA NA
GLN E:41 E:1143 71.0 0.394 E -103.0 117.7 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 GLN D:41 D:1143 69.0 0.383 E -104.2 124.5 NA NA NA
GLN E:41 E:1143 93.0 0.517 E -103.9 121.1 93.0 0.517 0.0 HOH
 3.582
 N
 O
GLN F:41 F:1143 71.0 0.394 E -102.4 120.5 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 GLN A:37 A:1143 73.0 0.406 E -110.0 126.9 73.0 0.406 0.0 HOH
 2.528
 CG
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 GLN A:41 A:1143 78.0 0.433 E -127.3 125.5 78.0 0.433 0.0 GOL
HOH
 9.335
2.636
 N
CG
 C3
O
GLN B:41 B:1143 101.0 0.561 E -125.0 129.2 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 GLN D:41 D:1143 68.0 0.378 E -109.9 131.3 68.0 0.378 0.0 HOH
 3.332
 N
 O
GLN E:41 E:1143 82.0 0.456 E -101.7 122.5 NA NA NA
GLN F:41 F:1143 78.0 0.433 E -114.2 122.8 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 GLN A:38 A:242 71.0 0.394 E -118.3 131.3 71.0 0.394 0.0
GLN B:38 B:242 74.0 0.411 E -92.5 112.2 74.0 0.411 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLN A:1143 A:1143 82.0 0.456 E -105.9 123.6