Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196715081 . C A CCDS1385.1:NM_000186.3:c.3445Cga>Aga_NP_000177.2:p.1149R>R Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 ARG A:106 X:1149 116.0 0.516 E -102.4 139.4 116.0 0.516 0.0 HOH
 2.950
 O
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 ARG B:51 B:1149 113.0 0.502 E -103.3 147.3 113.0 0.502 0.0 EDO
HOH
 7.016
4.444
 O
O
 O2
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 ARG A:51 A:1149 122.0 0.542 E -101.2 132.2 122.0 0.542 0.0 SO4
HOH
 3.375
2.763
 CD
O
 O3
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 ARG A:51 A:1149 121.0 0.538 E -100.0 134.6 121.0 0.538 0.0 HOH
 2.829
 NH2
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 ARG D:46 D:1149 115.0 0.511 E -114.4 124.4 115.0 0.511 0.0
ARG E:46 E:1149 138.0 0.613 E -110.7 137.3 NA NA NA
ARG F:46 F:1149 121.0 0.538 E -114.2 135.9 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 ARG C:51 C:1149 57.0 NA E -103.7 134.2 57.0 NA NA HOH
 8.141
 CA
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 ARG B:47 B:1149 103.0 0.458 E -122.2 118.0 103.0 0.458 0.0 HOH
 3.464
 NE
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 ARG D:47 D:1149 117.0 0.52 E -108.4 137.4 NA NA NA
ARG E:47 E:1149 116.0 0.516 E -111.9 135.1 NA NA NA
ARG F:47 F:1149 111.0 0.493 E -104.2 142.3 111.0 0.493 0.0 HOH
 3.055
 O
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 ARG A:47 F:1149 80.0 0.356 E -111.1 143.9 80.0 0.356 0.0 HOH
 6.545
 NH1
 O
ARG C:47 D:1149 116.0 0.516 E -118.2 137.2 NA NA NA
ARG E:47 E:1149 124.0 0.551 E -105.0 146.2 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 ARG D:47 D:1149 92.0 0.409 E -108.0 139.5 NA NA NA
ARG E:47 E:1149 121.0 0.538 E -102.6 140.6 121.0 0.538 0.0 HOH
 5.499
 O
 O
ARG F:47 F:1149 25.0 NA E -106.4 141.6 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 ARG A:43 A:1149 96.0 NA E -99.0 134.7 96.0 NA NA HOH
 2.832
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 ARG A:47 A:1149 175.0 0.778 E -111.3 127.7 175.0 0.778 0.0 HOH
 2.823
 O
 O
ARG B:47 B:1149 106.0 0.471 E -104.2 141.0 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 ARG D:47 D:1149 132.0 0.587 E -107.8 140.8 132.0 0.587 0.0 HOH
 3.187
 O
 O
ARG E:47 E:1149 139.0 0.618 E -114.1 126.7 NA NA NA
ARG F:47 F:1149 124.0 0.551 E -117.9 134.8 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 ARG A:44 A:248 97.0 0.431 E -110.7 126.8 97.0 0.431 0.0
ARG B:44 B:248 56.0 NA E -119.7 133.3 56.0 NA NA SO4
 6.554
 CD
 O4

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 ARG A:1149 A:1149 118.0 0.524 E -108.6 112.7