Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196715099 . G A CCDS1385.1:NM_000186.3:c.3463Gga>Aga_NP_000177.2:p.1155G>R Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 GLY A:112 X:1155 12.0 0.16 T 71.5 12.0 12.0 0.16 0.0 GOL
HOH
 3.636
2.785
 CA
O
 O3
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 GLY B:57 B:1155 24.0 0.32 T 73.0 2.5 24.0 0.32 0.0 HOH
 3.172
 O
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 GLY A:57 A:1155 26.0 0.347 T 82.6 2.1 23.0 0.307 0.04 A:P08603:0.04
 SO4
SO4
HOH
 6.014
3.847
3.725
 CA
O
CA
 O1
O2
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 GLY A:57 A:1155 26.0 0.347 T 86.1 -3.0 25.0 0.333 0.014 A:P08603:0.013
 SO4
HOH
 5.824
2.729
 CA
O
 O1
O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 GLY D:52 D:1155 31.0 0.413 S 48.3 30.6 31.0 0.413 0.0
GLY E:52 E:1155 32.0 0.427 T 69.0 27.4 NA NA NA
GLY F:52 F:1155 32.0 0.427 T 72.5 27.2 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 GLY C:57 C:1155 37.0 0.493 T 102.9 -29.3 37.0 0.493 0.0 HOH
 4.771
 O
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 GLY B:53 B:1155 32.0 0.427 T 95.3 1.3 32.0 0.427 0.0 HOH
 7.281
 O
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 GLY D:53 D:1155 28.0 0.373 T 63.3 8.9 NA NA NA
GLY E:53 E:1155 20.0 0.267 T 81.1 13.8 NA NA NA
GLY F:53 F:1155 13.0 0.173 T 75.0 6.1 13.0 0.173 0.0 HOH
 7.998
 N
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 GLY A:53 F:1155 22.0 0.293 S 74.2 29.3 22.0 0.293 0.0
GLY C:53 D:1155 17.0 0.227 T 63.2 14.8 NA NA NA
GLY E:53 E:1155 21.0 0.28 T 79.2 15.5 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 GLY D:53 D:1155 28.0 0.373 T 63.9 28.0 NA NA NA
GLY E:53 E:1155 19.0 0.253 T 64.7 28.4 19.0 0.253 0.0 HOH
 4.305
 O
 O
GLY F:53 F:1155 51.0 0.68 S 70.0 37.1 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 GLY A:49 A:1155 26.0 0.347 T 82.4 1.7 24.0 0.32 0.027 A:P08603:0.027
 HOH
 2.654
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 GLY A:53 A:1155 24.0 0.32 T 73.1 13.3 24.0 0.32 0.0 HOH
 2.708
 O
 O
GLY B:53 B:1155 17.0 0.227 T 79.6 5.1 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 GLY D:53 D:1155 26.0 0.347 T 69.5 14.4 26.0 0.347 0.0 HOH
 3.181
 O
 O
GLY E:53 E:1155 25.0 0.333 S 67.4 18.9 NA NA NA
GLY F:53 F:1155 20.0 0.267 T 93.0 -25.6 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 GLY A:50 A:254 30.0 0.4 T 71.9 3.9 18.0 0.24 0.16 B:Q03591:0.16
 SO4
 6.233
 CA
 O2
GLY B:50 B:254 35.0 0.467 T 70.1 -14.3 28.0 0.373 0.094 A:Q03591:0.093
 SO4
 5.592
 CA
 O4

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLY A:1155 A:1155 34.0 0.453 T 84.2 -0.1