Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196715109 . C A CCDS1385.1:NM_000186.3:c.3473tCa>tAa_NP_000177.2:p.1158S>* Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 SER A:115 X:1158 40.0 0.348 -64.5 166.9 40.0 0.348 0.0 HOH
 2.638
 OG
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 SER B:60 B:1158 15.0 0.13 -70.3 166.5 15.0 0.13 0.0 EDO
HOH
 4.157
3.674
 CB
C
 O2
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 SER A:60 A:1158 42.0 0.365 -70.4 178.0 42.0 0.365 0.0 SO4
SO4
HOH
 6.460
8.622
2.700
 OG
N
OG
 O4
O2
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 SER A:60 A:1158 43.0 0.374 -67.0 176.3 43.0 0.374 0.0 HOH
 2.724
 OG
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 SER D:55 D:1158 43.0 0.374 -63.0 162.6 43.0 0.374 0.0
SER E:55 E:1158 35.0 0.304 -69.0 166.5 NA NA NA
SER F:55 F:1158 45.0 0.391 -73.6 163.2 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 SER C:60 C:1158 50.0 0.435 -75.5 142.6 50.0 0.435 0.0 HOH
 7.025
 O
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 SER B:56 B:1158 53.0 0.461 -64.9 175.9 53.0 0.461 0.0 HOH
 4.782
 O
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 SER D:56 D:1158 36.0 0.313 -63.9 165.8 NA NA NA
SER E:56 E:1158 48.0 0.417 -63.1 166.8 NA NA NA
SER F:56 F:1158 50.0 0.435 -68.8 170.0 50.0 0.435 0.0 HOH
 2.745
 OG
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 SER A:56 F:1158 42.0 0.365 -56.9 172.1 42.0 0.365 0.0
SER C:56 D:1158 37.0 0.322 -61.3 168.5 NA NA NA
SER E:56 E:1158 44.0 0.383 -55.9 163.1 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 SER D:56 D:1158 36.0 0.313 -66.7 163.3 NA NA NA
SER E:56 E:1158 51.0 0.443 -65.1 162.8 51.0 0.443 0.0 HOH
 5.976
 N
 O
SER F:56 F:1158 32.0 0.278 -67.0 164.7 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 SER A:52 A:1158 41.0 0.357 -67.9 173.2 41.0 0.357 0.0 HOH
 2.733
 OG
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 SER A:56 A:1158 51.0 0.443 -68.5 166.2 51.0 0.443 0.0 HOH
 3.634
 CA
 O
SER B:56 B:1158 49.0 0.426 -63.8 164.9 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 SER D:56 D:1158 32.0 0.278 -67.2 160.5 32.0 0.278 0.0 HOH
 3.406
 OG
 O
SER E:56 E:1158 42.0 0.365 -67.7 166.0 NA NA NA
SER F:56 F:1158 52.0 0.452 -72.0 158.0 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 SER A:53 A:257 52.0 0.452 -66.0 172.8 52.0 0.452 0.0
SER B:53 B:257 27.0 0.235 -59.1 151.4 27.0 0.235 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 SER A:1158 A:1158 45.0 0.391 -64.8 161.9