Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716293 . G A CCDS1385.1:NM_000186.3:c.3546agG>agA_NP_000177.2:p.1182R>R Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 ARG A:139 X:1182 120.0 0.533 S -70.2 -41.2 120.0 0.533 0.0 HOH
 3.078
 O
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 ARG B:84 B:1182 117.0 0.52 T -71.4 155.1 27.0 0.12 0.4 A:W5SB08:0.4
 EDO
EDO
EDO
HOH
 9.532
8.955
6.354
3.002
 N
C
NH1
NE
 O1
C2
C2
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 ARG A:84 A:1182 119.0 0.529 S -67.7 -39.0 119.0 0.529 0.0 SO4
HOH
 3.636
2.912
 O
N
 O4
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 ARG A:84 A:1182 118.0 0.524 S -66.0 -44.6 118.0 0.524 0.0 HOH
 2.910
 O
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 ARG D:79 D:1182 129.0 0.573 S -72.1 -46.7 35.0 0.156 0.417 G:Q45001:0.418
ARG E:79 E:1182 21.0 NA S -99.1 168.2 NA NA NA
ARG F:79 F:1182 129.0 0.573 S -71.6 -48.1 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 ARG C:84 C:1182 111.0 0.493 S -76.3 -41.6 111.0 0.493 0.0 HOH
 2.876
 NH1
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 ARG B:80 B:1182 123.0 0.547 S -66.3 -42.3 44.0 0.196 0.351 A:E4QGX1:0.351
 SO4
HOH
 2.841
3.492
 NE
CD
 O4
O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 ARG D:80 D:1182 115.0 0.511 S -62.7 -38.1 NA NA NA
ARG E:80 E:1182 210.0 0.933 -72.5 360.0 NA NA NA
ARG F:80 F:1182 96.0 0.427 S -77.7 174.8 96.0 0.427 0.0 HOH
 2.612
 O
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 ARG A:80 F:1182 91.0 0.404 S -68.8 -51.8 91.0 0.404 0.0 BGC
GAL
SIA
 6.578
4.763
3.438
 O
NH2
N
 O6
O6
O9
ARG C:80 D:1182 114.0 0.507 S -56.9 -44.7 NA NA NA
ARG E:80 E:1182 124.0 0.551 S -65.8 -33.2 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 ARG D:80 D:1182 115.0 0.511 S -65.6 -37.8 NA NA NA
ARG E:80 E:1182 133.0 0.591 S -67.9 -35.9 133.0 0.591 0.0 BGC
GAL
NGA
SIA
HOH
 6.838
5.891
9.959
3.245
3.620
 O
NH2
NH2
N
CD
 C6
O6
O6
O9
O
ARG F:80 F:1182 118.0 0.524 T -71.7 -36.3 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 ARG A:76 A:1182 117.0 0.52 S -64.8 -43.9 117.0 0.52 0.0 HOH
 3.196
 N
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 ARG A:80 A:1182 105.0 0.467 T -69.7 -31.1 105.0 0.467 0.0 HOH
 3.031
 NH1
 O
ARG B:80 B:1182 125.0 0.556 S -69.6 -38.7 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 ARG D:80 D:1182 109.0 0.484 S -71.9 -37.3 109.0 0.484 0.0 HOH
 2.786
 NH1
 O
ARG E:80 E:1182 208.0 0.924 -64.7 360.0 NA NA NA
ARG F:80 F:1182 139.0 0.618 S -120.3 146.1 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 ARG A:77 A:281 118.0 NA -56.4 136.1 118.0 NA NA
ARG B:77 B:281 158.0 0.702 T -68.8 -57.6 158.0 0.702 0.0 SO4
 8.888
 NH1
 O4

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 ARG A:1182 A:1182 131.0 0.582 S -58.2 -34.5