Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716298 . C A CCDS1385.1:NM_000186.3:c.3551aCa>aAa_NP_000177.2:p.1184T>K Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 THR A:141 X:1184 118.0 0.843 -84.1 61.7 118.0 0.843 0.0 HOH
 2.861
 OG1
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 THR B:86 B:1184 70.0 0.5 -141.7 156.5 33.0 0.236 0.264 A:W5SB08:0.264
 EDO
EDO
SO4
HOH
 8.690
7.450
6.879
3.368
 O
C
OG1
O
 O1
C2
O1
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 THR A:86 A:1184 114.0 0.814 T -72.1 -13.8 99.0 0.707 0.107 A:P08603:0.007
A:P08603:0.107
 SO4
SO4
HOH
 2.831
9.078
3.164
 N
CB
O
 O4
O2
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 THR A:86 A:1184 114.0 0.814 T -58.6 -29.6 80.0 0.571 0.243 A:P08603:0.243
 HOH
 2.931
 OG1
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 THR D:81 D:1184 52.0 0.371 -142.5 158.4 26.0 0.186 0.185 G:Q45001:0.186
THR E:81 E:1184 54.0 0.386 S 175.2 139.9 NA NA NA
THR F:81 F:1184 63.0 0.45 -140.3 158.2 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 THR C:86 C:1184 102.0 0.729 -58.5 23.4 24.0 0.171 0.558 B:P01024:0.557
 HOH
 3.713
 OG1
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 THR B:82 B:1184 64.0 0.457 -116.5 161.3 36.0 0.257 0.2 A:E4QGX1:0.2
 SO4
 8.523
 N
 O4
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 THR D:82 D:1184 95.0 0.679 S -85.6 -8.7 NA NA NA
THR E:82 NA:NA DO NA DO DO DO NA NA NA
THR F:82 F:1184 97.0 0.693 -52.1 142.6 97.0 0.693 0.0 HOH
 5.222
 N
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 THR A:82 F:1184 69.0 0.493 -74.9 170.0 69.0 0.493 0.0 BGC
GAL
SIA
 6.016
7.103
4.234
 N
CG2
N
 O6
O2
O9
THR C:82 D:1184 94.0 0.671 -98.7 -6.0 NA NA NA
THR E:82 E:1184 74.0 0.529 -130.4 159.9 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 THR D:82 D:1184 97.0 0.693 -88.4 -10.0 NA NA NA
THR E:82 E:1184 166.0 1.0 -145.8 360.0 166.0 1.0 0.0 BGC
GAL
SIA
HOH
 5.709
6.700
4.986
4.400
 N
N
N
N
 O6
O2
C9
O
THR F:82 F:1184 114.0 0.814 51.4 61.1 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 THR A:78 A:1184 112.0 0.8 T -69.1 -21.3 99.0 0.707 0.093 A:P08603:0.093
 HOH
 2.928
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 ARG A:82 A:1184 204.0 0.907 T -62.6 -30.8 204.0 0.907 0.0 HOH
 2.633
 O
 O
ARG B:82 B:1184 200.0 0.889 T -74.6 -39.3 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 THR D:82 D:1184 94.0 0.671 S -100.4 -9.6 94.0 0.671 0.0 HOH
 2.796
 N
 O
THR E:82 NA:NA DO NA DO DO DO NA NA NA
THR F:82 F:1184 67.0 0.479 -55.1 171.0 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 THR A:79 A:283 88.0 0.629 G -69.1 -2.7 88.0 0.629 0.0
THR B:79 B:283 110.0 0.786 S -51.9 -40.5 110.0 0.786 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 THR A:1184 A:1184 121.0 0.864 T -70.7 -22.2