Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716309 . A C CCDS1385.1:NM_000186.3:c.3562Aag>Cag_NP_000177.2:p.1188K>Q Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
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label_seq_id: 
label_comp_id: 
auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 LYS A:145 X:1188 81.0 0.405 -76.2 106.4 81.0 0.405 0.0 HOH
 2.948
 CE
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 LYS B:90 B:1188 133.0 0.665 -120.0 137.0 133.0 0.665 0.0 SO4
SO4
HOH
 3.310
3.830
2.789
 CG
NZ
NZ
 O1
O2
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 LYS A:90 A:1188 76.0 0.38 -83.2 70.5 51.0 0.255 0.125 A:P08603:0.125
 SO4
HOH
 9.668
2.832
 N
N
 O3
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 LYS A:90 A:1188 73.0 0.365 -84.6 70.6 51.0 0.255 0.11 A:P08603:0.11
 HOH
 2.852
 O
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 LYS D:85 D:1188 114.0 0.57 -132.7 142.1 61.0 0.305 0.265 A:P01024:0.265
LYS E:85 E:1188 113.0 0.565 -132.3 140.0 NA NA NA
LYS F:85 F:1188 111.0 0.555 -132.0 141.2 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 LYS C:90 C:1188 93.0 0.465 E -141.1 136.1 40.0 0.2 0.265 A:P01024:0.265
 HOH
 3.090
 NZ
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 LYS B:86 B:1188 35.0 NA -133.6 157.3 35.0 NA NA
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 LYS D:86 D:1188 112.0 0.56 -110.1 142.7 NA NA NA
LYS E:86 E:1188 71.0 0.355 -80.8 112.8 NA NA NA
LYS F:86 NA:NA DO NA DO DO DO NA NA NA
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 LYS A:86 F:1188 106.0 0.53 -161.0 154.3 60.0 0.3 0.23 D:P01024:0.23
 SIA
HOH
 8.368
4.699
 O
NZ
 O10
O
LYS C:86 D:1188 149.0 0.745 -122.4 145.3 NA NA NA
LYS E:86 E:1188 144.0 0.72 -117.5 85.5 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 LYS D:86 D:1188 105.0 NA -100.4 144.5 NA NA NA
LYS E:86 E:1188 105.0 NA 360.0 96.6 105.0 NA NA GAL
SIA
HOH
 9.286
2.892
6.860
 CB
CB
CB
 O3
O10
O
LYS F:86 F:1188 119.0 0.595 -125.9 141.9 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 LYS A:82 A:1188 83.0 0.415 -83.2 71.7 61.0 0.305 0.11 A:P08603:0.11
 HOH
 2.777
 NZ
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 LYS A:86 A:1188 156.0 0.78 -74.0 150.9 156.0 0.78 0.0 HOH
 2.635
 O
 O
LYS B:86 B:1188 137.0 0.685 -79.8 149.9 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 LYS D:86 D:1188 79.0 0.395 -72.3 129.0 79.0 0.395 0.0 HOH
 3.188
 CG
 O
LYS E:86 E:1188 95.0 0.475 -69.6 139.8 NA NA NA
LYS F:86 F:1188 107.0 0.535 -125.2 155.8 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 LYS A:83 A:287 81.0 NA -91.5 76.5 81.0 NA NA
LYS B:83 B:287 118.0 0.59 -73.9 134.4 118.0 0.59 0.0 SO4
 5.544
 CE
 O3

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 LYS A:1188 A:1188 89.0 0.445 -81.4 73.3