Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716327 . G A CCDS1385.1:NM_000186.3:c.3580Ggt>Agt_NP_000177.2:p.1194G>S Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
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auth_asym_id: 
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alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 GLY A:151 X:1194 44.0 0.587 T 95.6 -17.7 44.0 0.587 0.0 GOL
HOH
 2.673
2.718
 O
O
 O2
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 GLY B:96 B:1194 44.0 0.587 T 93.2 -17.7 44.0 0.587 0.0 HOH
 3.878
 CA
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 GLY A:96 A:1194 53.0 0.707 T 93.8 -14.0 53.0 0.707 0.0 SO4
HOH
 7.837
4.463
 O
CA
 O3
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 GLY A:96 A:1194 55.0 0.733 T 96.4 -15.7 55.0 0.733 0.0 SO4
HOH
 7.499
2.792
 O
O
 O3
O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 GLY D:91 D:1194 38.0 0.507 T 97.3 -16.2 12.0 0.16 0.347 G:Q45001:0.347
GLY E:91 E:1194 47.0 0.627 T 106.5 -16.9 NA NA NA
GLY F:91 F:1194 38.0 0.507 T 105.4 -15.2 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 GLY C:96 C:1194 41.0 0.547 T 103.1 -27.7 41.0 0.547 0.0 HOH
 5.886
 N
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 GLY B:92 B:1194 45.0 0.6 T 108.9 -5.6 15.0 0.2 0.4 A:E4QGX1:0.4
 HOH
 6.063
 N
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 GLY D:92 D:1194 46.0 0.613 T 95.2 -20.9 NA NA NA
GLY E:92 E:1194 42.0 0.56 T 89.0 -5.7 NA NA NA
GLY F:92 F:1194 43.0 0.573 T 92.5 -11.3 43.0 0.573 0.0 HOH
 4.537
 O
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 GLY A:92 F:1194 52.0 0.693 T 100.7 10.1 52.0 0.693 0.0 SIA
HOH
 7.263
8.833
 O
N
 O4
O
GLY C:92 D:1194 47.0 0.627 T 84.4 -14.9 NA NA NA
GLY E:92 E:1194 40.0 0.533 T 92.9 -12.3 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 GLY D:92 D:1194 46.0 0.613 T 88.4 -16.8 NA NA NA
GLY E:92 E:1194 40.0 0.533 T 90.4 -15.5 40.0 0.533 0.0 NGA
GAL
SIA
HOH
 8.497
7.632
7.390
4.524
 O
O
O
CA
 C5
O6
O1B
O
GLY F:92 F:1194 43.0 0.573 T 94.8 -15.6 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 GLY A:88 A:1194 48.0 0.64 T 91.7 -16.0 48.0 0.64 0.0 HOH
 2.852
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 GLY A:92 A:1194 42.0 0.56 T 95.5 -12.1 42.0 0.56 0.0 HOH
 2.850
 O
 O
GLY B:92 B:1194 48.0 0.64 T 97.6 -14.0 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 GLY D:92 D:1194 46.0 0.613 T 97.2 -21.8 46.0 0.613 0.0 HOH
 6.091
 N
 O
GLY E:92 E:1194 44.0 0.587 T 89.9 -9.4 NA NA NA
GLY F:92 F:1194 45.0 0.6 T 101.4 -3.2 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 GLY A:89 A:293 48.0 0.64 T 101.5 -27.3 48.0 0.64 0.0
GLY B:89 B:293 56.0 0.747 T 85.0 -8.5 56.0 0.747 0.0 SO4
SO4
 7.820
3.620
 O
O
 O2
O1

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLY A:1194 A:1194 45.0 0.6 T 87.8 -12.1