Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716330 . G A CCDS1385.1:NM_000186.3:c.3583Gaa>Aaa_NP_000177.2:p.1195E>K Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
auth_asym_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 GLU A:152 X:1195 78.0 0.411 -82.1 142.5 78.0 0.411 0.0 GOL
GOL
HOH
 3.820
9.540
2.772
 N
OE2
OE1
 O1
O2
O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 GLU B:97 B:1195 76.0 0.4 -87.0 151.3 37.0 0.195 0.205 A:W5SB08:0.205
 HOH
 2.935
 OE2
 O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 GLU A:97 A:1195 65.0 0.342 -93.4 143.1 48.0 0.253 0.089 A:P08603:0.089
 SO4
HOH
 7.493
2.617
 O
OE1
 O4
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 GLU A:97 A:1195 67.0 0.353 -90.8 147.1 51.0 0.268 0.085 A:P08603:0.084
 SO4
HOH
 7.032
2.601
 O
OE2
 O4
O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 GLU D:92 D:1195 91.0 0.479 -80.1 136.5 6.0 0.032 0.447 G:Q45001:0.447
GLU E:92 E:1195 88.0 0.463 -80.3 137.2 NA NA NA
GLU F:92 F:1195 90.0 0.474 -79.5 136.2 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 GLU C:97 C:1195 93.0 0.489 -81.0 142.2 93.0 0.489 0.0 HOH
 7.444
 N
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 GLU B:93 B:1195 84.0 0.442 -94.1 131.0 6.0 0.032 0.41 A:E4QGX1:0.411
 HOH
 2.171
 OE2
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 GLU D:93 D:1195 86.0 0.453 -82.1 141.1 NA NA NA
GLU E:93 E:1195 59.0 0.311 -95.5 140.1 NA NA NA
GLU F:93 F:1195 83.0 0.437 -86.5 144.5 83.0 0.437 0.0 HOH
 2.565
 OE1
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 GLU A:93 F:1195 91.0 0.479 E -130.0 154.2 91.0 0.479 0.0 GAL
SIA
 7.949
2.776
 OE2
OE2
 O3
C11
GLU C:93 D:1195 81.0 0.426 -89.3 147.0 NA NA NA
GLU E:93 E:1195 91.0 0.479 -96.5 148.9 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 GLU D:93 D:1195 83.0 0.437 -87.1 150.9 NA NA NA
GLU E:93 E:1195 69.0 0.363 -90.3 151.7 69.0 0.363 0.0 GAL
NGA
GAL
SIA
HOH
 7.472
8.400
8.856
3.092
3.506
 CG
CG
CG
OE1
C
 O3
N2
C1
C11
O
GLU F:93 F:1195 98.0 0.516 -89.2 156.8 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 GLU A:89 A:1195 72.0 0.379 -84.4 150.4 51.0 0.268 0.111 A:P08603:0.111
 HOH
 2.751
 OE1
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 GLU A:93 A:1195 76.0 0.4 -86.1 143.2 76.0 0.4 0.0 HOH
 3.550
 CA
 O
GLU B:93 B:1195 88.0 0.463 -79.3 143.0 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 GLU D:93 D:1195 75.0 0.395 -77.5 141.2 75.0 0.395 0.0 HOH
 2.868
 OE1
 O
GLU E:93 E:1195 51.0 0.268 -93.0 143.5 NA NA NA
GLU F:93 F:1195 75.0 0.395 -90.9 160.9 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 GLU A:90 A:294 68.0 0.358 -73.1 145.9 68.0 0.358 0.0
GLU B:90 B:294 62.0 0.326 -95.4 144.9 62.0 0.326 0.0 SO4
SO4
 7.028
3.503
 O
CA
 O3
O3

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLU A:1195 A:1195 68.0 0.358 -81.3 136.3