Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716342 . T A CCDS1385.1:NM_000186.3:c.3595Ttt>Att_NP_000177.2:p.1199F>I Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
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label_comp_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 PHE A:156 X:1199 0.0 0.0 E -107.5 171.3 0.0 0.0 0.0 HOH
 2.858
 O
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 PHE B:101 B:1199 3.0 0.014 E -119.1 166.7 3.0 0.014 0.0 EDO
EDO
HOH
 9.944
7.163
2.690
 C
O
O
 O1
O2
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 PHE A:101 A:1199 0.0 0.0 E -108.4 168.0 0.0 0.0 0.0 SO4
HOH
 9.183
2.692
 CE2
O
 O4
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 PHE A:101 A:1199 0.0 0.0 E -109.0 168.9 0.0 0.0 0.0 SO4
HOH
 9.110
2.783
 CE2
O
 O4
O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 PHE D:96 D:1199 2.0 0.01 E -106.1 174.9 2.0 0.01 0.0
PHE E:96 E:1199 0.0 0.0 B -86.5 156.0 NA NA NA
PHE F:96 F:1199 1.0 0.005 E -112.3 174.8 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 PHE C:101 C:1199 1.0 0.005 E -99.9 170.5 1.0 0.005 0.0 HOH
 2.703
 O
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 PHE B:97 B:1199 0.0 0.0 E -104.2 176.5 0.0 0.0 0.0 SO4
HOH
 7.175
2.355
 O
O
 O1
O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 PHE D:97 D:1199 0.0 0.0 E -106.8 164.2 NA NA NA
PHE E:97 E:1199 2.0 0.01 E -90.1 161.9 NA NA NA
PHE F:97 F:1199 2.0 0.01 E -118.2 160.7 2.0 0.01 0.0 HOH
 5.136
 O
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 PHE A:97 F:1199 0.0 0.0 E -121.5 168.7 0.0 0.0 0.0 GAL
SIA
 9.084
5.389
 O
N
 O6
O9
PHE C:97 D:1199 0.0 0.0 E -108.8 167.9 NA NA NA
PHE E:97 E:1199 0.0 0.0 E -106.1 171.5 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 PHE D:97 D:1199 0.0 0.0 E -103.5 168.6 NA NA NA
PHE E:97 E:1199 2.0 0.01 E -106.9 169.8 2.0 0.01 0.0 GAL
SIA
HOH
 9.234
4.874
2.728
 N
N
O
 O6
O9
O
PHE F:97 F:1199 28.0 0.133 -106.4 360.0 NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 PHE A:93 A:1199 1.0 0.005 E -109.2 167.5 1.0 0.005 0.0 HOH
 2.760
 O
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 PHE A:97 A:1199 0.0 0.0 E -118.1 166.8 0.0 0.0 0.0 HOH
 2.840
 O
 O
PHE B:97 B:1199 1.0 0.005 E -111.0 168.0 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 PHE D:97 D:1199 0.0 0.0 E -99.8 155.7 0.0 0.0 0.0 HOH
 4.038
 O
 O
PHE E:97 E:1199 2.0 0.01 E -86.5 157.1 NA NA NA
PHE F:97 F:1199 6.0 0.029 E -105.4 161.8 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 PHE A:94 A:298 4.0 0.019 E -99.5 159.4 4.0 0.019 0.0
PHE B:94 B:298 0.0 0.0 E -93.4 -171.5 0.0 0.0 0.0 SO4
 9.549
 CD2
 O4

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 PHE A:1199 A:1199 3.0 0.014 E -103.9 162.6