Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716345 . G A CCDS1385.1:NM_000186.3:c.3598Gtg>Atg_NP_000177.2:p.1200V>M Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 

PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 VAL A:157 X:1200 47.0 0.303 E -136.5 155.6 47.0 0.303 0.0 HOH
 3.763
 CA
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 VAL B:102 B:1200 57.0 0.368 E -135.9 156.4 5.0 0.032 0.336 A:W5SB08:0.335
 EDO
EDO
EDO
HOH
 6.147
9.495
9.215
3.452
 CG2
CG2
N
CG2
 O1
O1
O2
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 VAL A:102 A:1200 49.0 0.316 E -133.4 156.3 49.0 0.316 0.0 SO4
HOH
 8.363
3.604
 CG2
CG2
 O4
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 VAL A:102 A:1200 50.0 0.323 E -135.2 156.9 50.0 0.323 0.0 HOH
 3.615
 CG2
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 VAL D:97 D:1200 56.0 0.361 E -137.5 152.7 56.0 0.361 0.0
VAL E:97 E:1200 62.0 0.4 -134.9 27.5 NA NA NA
VAL F:97 F:1200 65.0 0.419 E -146.8 161.0 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 VAL C:102 C:1200 47.0 0.303 E -129.5 158.1 34.0 0.219 0.084 B:P01024:0.084
 HOH
 3.521
 CG1
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 VAL B:98 B:1200 51.0 0.329 E -136.9 171.2 51.0 0.329 0.0 SO4
HOH
 4.904
3.734
 CG1
CG1
 O1
O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 VAL D:98 D:1200 35.0 0.226 E -137.0 156.2 NA NA NA
VAL E:98 E:1200 40.0 0.258 E -133.5 148.0 NA NA NA
VAL F:98 F:1200 53.0 0.342 E -130.5 153.1 53.0 0.342 0.0 HOH
 3.906
 CA
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 VAL A:98 F:1200 65.0 0.419 E -124.1 175.9 65.0 0.419 0.0 GAL
SIA
 9.622
7.038
 CG1
N
 O6
O9
VAL C:98 D:1200 33.0 0.213 E -134.8 159.2 NA NA NA
VAL E:98 E:1200 48.0 0.31 E -139.6 155.3 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 VAL D:98 D:1200 32.0 0.206 E -138.2 155.4 NA NA NA
VAL E:98 E:1200 46.0 0.297 E -138.8 154.0 46.0 0.297 0.0 SIA
HOH
 6.713
3.536
 N
CG1
 O9
O
VAL F:98 NA:NA DO NA DO DO DO NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 VAL A:94 A:1200 48.0 0.31 E -131.1 156.4 48.0 0.31 0.0 HOH
 3.613
 CG2
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 VAL A:98 A:1200 52.0 0.335 E -131.7 158.2 52.0 0.335 0.0 HOH
 3.517
 CG2
 O
VAL B:98 B:1200 55.0 0.355 E -137.5 160.0 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 VAL D:98 D:1200 39.0 0.252 E -125.1 150.6 39.0 0.252 0.0 HOH
 3.408
 CG2
 O
VAL E:98 E:1200 41.0 0.265 E -128.2 144.0 NA NA NA
VAL F:98 F:1200 59.0 0.381 E -135.9 -169.4 NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 VAL A:95 A:299 57.0 0.368 E -131.0 163.2 57.0 0.368 0.0
VAL B:95 B:299 61.0 0.394 E -168.0 151.4 61.0 0.394 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 VAL A:1200 A:1200 53.0 0.342 E -134.6 146.3