Variant

Genome Chromosome Position VCF ID Ref Alt mRNA Change mRNA Info
GRCh37 chr1 196716357 . G A CCDS1385.1:NM_000186.3:c.3610Gga>Aga_NP_000177.2:p.1204G>R Homo sapiens complement factor H (CFH), transcript variant 1, mRNA.
pdb_id: 
label_asym_id: 
label_seq_id: 
label_comp_id: 
auth_asym_id: 
auth_seq_id: 
alphafold_id: 
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PDB

Entity Residue Monomer BioUnit Ligand View
PDB Entity Uniprot Identity Evalue ExpMethod Date Name Label Auth ASA rASA SS φ ψ ASA rASA ΔASA Interaction Name Distance Atom(p) Atom(l)
3sw0 1 P08603 100.0 2e-126 X-RAY
 2012-03-14 GLY A:161 X:1204 32.0 0.427 T 100.6 3.0 32.0 0.427 0.0 HOH
 7.699
 O
 O
6zh1 2 P08603 100.0 4e-83 X-RAY
 2022-01-12 GLY B:106 B:1204 23.0 0.307 T 95.9 2.2 16.0 0.213 0.094 A:W5SB08:0.093
 EDO
SO4
HOH
 6.252
6.946
2.864
 N
O
N
 O2
O4
O
3kxv 1 P08603 99.22 5e-83 X-RAY
 2010-05-19 GLY A:106 A:1204 54.0 0.72 T 100.6 3.6 54.0 0.72 0.0 SO4
HOH
 6.765
3.308
 O
N
 O3
O
3kzj 1 P08603 99.22 6e-83 X-RAY
 2010-05-19 GLY A:106 A:1204 62.0 0.827 T 97.4 6.9 62.0 0.827 0.0 HOH
 4.247
 N
 O
5nbq 2 P08603 100.0 3e-82 X-RAY
 2017-12-06 GLY D:101 D:1204 51.0 0.68 T 108.5 -24.9 51.0 0.68 0.0
GLY E:101 E:1204 92.0 1.0 T 80.9 -6.0 NA NA NA
GLY F:101 F:1204 85.0 1.0 T 74.5 45.5 NA NA NA
2xqw 2 P08603 98.45 5e-82 X-RAY
 2011-02-02 GLY C:106 C:1204 38.0 0.507 T 86.8 16.1 35.0 0.467 0.04 B:P01024:0.04
 HOH
 4.057
 CA
 O
4j38 2 P08603 98.45 6e-82 X-RAY
 2013-05-15 GLY B:102 B:1204 81.0 1.0 T 114.8 -40.6 81.0 1.0 0.0 HOH
 5.927
 O
 O
3oxu 2 Q14006 100.0 4e-81 X-RAY
 2011-02-16 GLY D:102 D:1204 34.0 0.453 T 94.3 7.0 NA NA NA
GLY E:102 E:1204 52.0 0.693 T 98.4 -5.1 NA NA NA
GLY F:102 F:1204 47.0 0.627 T 77.5 16.0 47.0 0.627 0.0 HOH
 2.573
 N
 O
4ont 1 P08603 100.0 4e-81 X-RAY
 2014-11-26 GLY A:102 F:1204 55.0 0.733 T 111.0 59.5 55.0 0.733 0.0
GLY C:102 D:1204 40.0 0.533 T 95.7 0.4 NA NA NA
GLY E:102 E:1204 24.0 0.32 T 74.5 2.1 NA NA NA
4zh1 2 P08603 100.0 4e-81 X-RAY
 2016-01-13 GLY D:102 D:1204 39.0 0.52 T 95.2 -7.5 NA NA NA
GLY E:102 E:1204 36.0 0.48 T 87.9 -5.0 36.0 0.48 0.0 HOH
 2.250
 N
 O
GLY F:102 NA:NA DO NA DO DO DO NA NA NA
2g7i 1 P08603 100.0 6e-81 X-RAY
 2006-05-23 GLY A:98 A:1204 51.0 0.68 T 92.9 18.6 51.0 0.68 0.0 HOH
 6.689
 N
 O
3r62 1 P08603 99.2 3e-80 X-RAY
 2011-06-29 GLY A:102 A:1204 36.0 0.48 T 75.7 14.2 36.0 0.48 0.0 HOH
 2.545
 O
 O
GLY B:102 B:1204 30.0 0.4 T 81.2 9.4 NA NA NA
3rj3 2 Q03591 99.2 3e-80 X-RAY
 2012-03-14 GLY D:102 D:1204 35.0 0.467 T 98.5 1.3 35.0 0.467 0.0 HOH
 2.804
 N
 O
GLY E:102 E:1204 33.0 0.44 T 99.5 -3.3 NA NA NA
GLY F:102 NA:NA DO NA DO DO DO NA NA NA
4muc 1 Q03591 98.4 1e-79 X-RAY
 2015-02-18 GLY A:99 A:303 87.0 1.0 T 108.8 -55.2 87.0 1.0 0.0
GLY B:99 B:303 50.0 0.667 T 100.0 3.8 50.0 0.667 0.0

AlphaFold DB

Entity Residue Monomer View
ID Entity Uniprot Identity Evalue Name Label Auth ASA rASA SS φ ψ
af-p08603-f1 1 P08603 99.92 0.0 GLY A:1204 A:1204 36.0 0.48 T 98.6 -4.8